Patents by Inventor Robert B. Scharpf

Robert B. Scharpf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE MOLECULE GENOME-WIDE MUTATION AND FRAGMENTATION PROFILES OF CELL-FREE DNA
    Publication number: 20250131982
    Abstract: Methods for non-invasive cancer detection use a combination of genome-wide mutation and fragmentation features of cfDNA that facilitate cancer screening.
    Type: Application
    Filed: December 15, 2022
    Publication date: April 24, 2025
    Inventors: Victor E. Velculescu, Robert B. Scharpf, Daniel C. Bruhm
  • DETECTION OF LUNG CANCER USING CELL-FREE DNA FRAGMENTATION
    Publication number: 20240060141
    Abstract: Cell free DNA (cfDNA) fragmentation for lung cancer detection is combined with current imaging-based screening methods and biomarkers.
    Type: Application
    Filed: December 21, 2021
    Publication date: February 22, 2024
    Inventors: Victor Velculescu, Robert B. Scharpf, Dimitrios Mathios, Jillian A. Phallen, Daniel Bruhm, Stephen Cristiano
  • CELL-FREE DNA FOR ASSESSING AND/OR TREATING CANCER
    Publication number: 20220325343
    Abstract: This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having cancer (e.g., a localized cancer) are provided. For example, methods and materials for assessing, monitoring, and/or treating a mammal having cancer are provided.
    Type: Application
    Filed: June 17, 2022
    Publication date: October 13, 2022
    Inventors: Victor E. Velculescu, Stephen Cristiano, Alessandro Leal, Jillian A. Phallen, Jacob Fiksel, Vilmos Adleff, Robert B. Scharpf
  • METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER
    Publication number: 20210355545
    Abstract: This document relates to methods and materials for assessing and/or treating mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as being likely to respond to a particular cancer treatment, and, optionally, for treating the mammal, are provided.
    Type: Application
    Filed: October 15, 2019
    Publication date: November 18, 2021
    Inventors: Victor E. Velculescu, Robert B. Scharpf, Eniko Papp, Dorothy Hallberg, Dennis Slamon, Gottfried Konecny
  • CELL-FREE DNA FOR ASSESSING AND/OR TREATING CANCER
    Publication number: 20210254152
    Abstract: This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having cancer (e.g., a localized cancer) are provided. For example, methods and materials for assessing, monitoring, and/or treating a mammal having cancer are provided.
    Type: Application
    Filed: March 17, 2021
    Publication date: August 19, 2021
    Inventors: Victor E. Velculescu, Stephen Cristiano, Alessandro Leal, Jillian A. Phallen, Jacob Fiksel, Vilmos Adleff, Robert B. Scharpf
  • CELL-FREE DNA FOR ASSESSING AND/OR TREATING CANCER
    Publication number: 20210198747
    Abstract: This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having cancer (e.g., a localized cancer) are provided. For example, methods and materials for assessing, monitoring, and/or treating a mammal having cancer are provided.
    Type: Application
    Filed: May 17, 2019
    Publication date: July 1, 2021
    Inventors: Victor E. Velculescu, Stephen Cristiano, Alessandro Leal, Jillian A. Phallen, Jacob Fiksel, Vilmos Adleff, Robert B. Scharpf
  • Cell-free DNA for assessing and/or treating cancer
    Patent number: 10982279
    Abstract: This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having cancer (e.g., a localized cancer) are provided. For example, methods and materials for assessing, monitoring, and/or treating a mammal having cancer are provided.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: April 20, 2021
    Assignee: The Johns Hopkins University
    Inventors: Victor E. Velculescu, Stephen Cristiano, Alessandro Leal, Jillian A. Phallen, Jacob Fiksel, Vilmos Adleff, Robert B. Scharpf
  • Cell-free DNA for assessing and/or treating cancer
    Patent number: 10975431
    Abstract: This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having cancer (e.g., a localized cancer) are provided. For example, methods and materials for assessing, monitoring, and/or treating a mammal having cancer are provided.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: April 13, 2021
    Assignee: The Johns Hopkins University
    Inventors: Victor E. Velculescu, Stephen Cristiano, Alessandro Leal, Jillian A. Phallen, Jacob Fiksel, Vilmos Adleff, Robert B. Scharpf
  • CELL-FREE DNA FOR ASSESSING AND/OR TREATING CANCER
    Publication number: 20200149118
    Abstract: This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having cancer (e.g., a localized cancer) are provided. For example, methods and materials for assessing, monitoring, and/or treating a mammal having cancer are provided.
    Type: Application
    Filed: December 30, 2019
    Publication date: May 14, 2020
    Inventors: Victor E. Velculescu, Stephen Cristiano, Alessandro Leal, Jillian A. Phallen, Jacob Fiksel, Vilmos Adleff, Robert B. Scharpf
  • CELL-FREE DNA FOR ASSESSING AND/OR TREATING CANCER
    Publication number: 20200131571
    Abstract: This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having cancer (e.g., a localized cancer) are provided. For example, methods and materials for assessing, monitoring, and/or treating a mammal having cancer are provided.
    Type: Application
    Filed: December 30, 2019
    Publication date: April 30, 2020
    Inventors: Victor E. Velculescu, Stephen Cristiano, Alessandro Leal, Jillian A. Phallen, Jacob Fiksel, Vilmos Adleff, Robert B. Scharpf