Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: The present invention relates to spray drying plasma methodology that includes pretreating a donated liquid plasma unit, drying the liquid plasma using a spray drying apparatus with the spray drying disposable device that results in a disposable having the dried plasma, finishing the disposable using the finishing apparatus that is designed to seal and separate the disposable, and transform the disposable into a dried plasma unit. The methods of the present invention include storing the dried plasma unit and, when ready for use, reconstituting the dried plasma unit with reconstitution solution to obtain a plasma unit ready for transfusion into a recipient.

Abstract: The present invention includes an ease-of-use system that allows the spray drying disposable device to fit (e.g., align) in both spray drying apparatus and the spray drying finishing apparatus to safely operate the system. The system includes locating arrangements between the spray drying disposable and the spray drying apparatus and/or spray drying finishing apparatus, a first retainer and second retainer, a shorter disposable device that allows for effective spray drying of plasma, a feedback indicators of correct installment, redundant indicators of correct installment, easily accessible operator controls and emergency shut offs.

Abstract: An alignment system that allows a spray drying disposable to align in both spray drying apparatus and finishing apparatus. The first instance is a locating arrangement wherein a locator is disposed on the spray drying apparatus and/or finishing apparatus and another locator is on the spray drying head of the disposable such that the locators allow for alignment of the disposable with the spray drying apparatus or finishing apparatus. A second instance of an alignment element includes a guide that is offset as positioned on the spray drying head of the disposable. Yet a third instance of the alignment arrangement relates to the gas exhaust port. In a fourth instance, the alignment system includes a positioning arrangement to reversibly attach the outer wall of the disposable to the finishing apparatus. In a fifth and sixth instance, a retaining device that retains the spray drying head in the spray drying apparatus and/or finishing apparatus.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: Methods, systems, and apparatuses involving disinfecting light subcomponents are provided. An example system comprises a substrate with one or more light emitters disposed on the substrate. The one or more light emitters may be configured to inactivate microorganisms on a surface by emitting light. The light may comprise a proportion of spectral energy of the light, measured in a 380 nanometers (nm) to 420 nm wavelength range, greater than 50%. The light may comprise a full width half max (FWHM) emission spectrum of less than 20 nm and centered at a wavelength of approximately 405 nm to concentrate a spectral energy of the light and minimize energy associated with wavelengths that bleed into an ultraviolet wavelength range. The light may comprise an irradiance at the surface sufficient to initiate inactivation of microorganisms on the surface.

Abstract: A system may include an area configured to accept an object for disinfection, a first light emitter configured to emit a first light within a wavelength range of 380-420 nanometers (nm) and having a first intensity, and a second light emitter configured to emit a second light within a wavelength range of 380-420 nanometers (nm) and having a second intensity, wherein the first intensity and the second intensity comprise an intensity sufficient to initiate inactivation of microorganisms, and wherein the first light and the second light create a multi-dimensional space of disinfection.

Abstract: Radiant energy control systems, methods, and apparatuses are provided. An example light emitting device may comprise a sensor operable to detect whether a space is occupied, and a controller in communication with the sensor and operable to cause output, via a first light emitter white light comprising a wavelength range of 380 to 420 nm, and cause output, via a second light emitter a non-white light comprising a wavelength range of 380 to 420 nm.

Abstract: Systems and methods for bacterial load sensing devices are disclosed. An example contamination sensing device may comprise a body, a light emitter disposed on the body and configured to emit an excitation wavelength of light toward a surface, a sensor disposed on the body, configured to detect light, and directed toward the surface, and a filter adjuster configured to determine, based on the excitation wavelength of light, a filter configured to remove light outside of an emission wavelength range, wherein the emission wavelength range corresponds to wavelengths of light emitted by contamination upon exposure to the excitation wavelength of light, and adjustably move the filter in front of the sensor.

Abstract: A method and system for disinfecting air purification and heating, ventilation, air conditioning (HVAC) devices may include a fibrous media filter, an antimicrobial filter layer positioned adjacent to one or more surfaces of the fibrous media filter, and one or more light emitters positioned within the antimicrobial filter layer and configured to emit a disinfecting light. The disinfecting light may include an irradiance sufficient to inactivate microorganisms on the fibrous media filter, and the disinfecting light may include a wavelength from about 380 nm to about 420 nm.

Abstract: Methods, systems, and devices for inactivating microorganisms are disclosed. An example light emitting device that inactivates microorganisms on a surface comprises a light emitter configured to emit a first light comprising a first wavelength in a range of 380 nanometers (nm) to 420 nm, a first light-converting material configured to convert a first portion of the first light to at least a second light comprising a second wavelength different from the first wavelength, and a second light-converting material configured to convert a second portion of the first light to at least a third light comprising a third wavelength different from the first wavelength, wherein at least the first light, the second light, and the third light mix to form a disinfecting white light.

Abstract: Methods, systems, and apparatuses involving devices with disinfecting illumination are provided. An example apparatus comprises a container comprising a first side and a second side, a first array of light emitters disposed on the first side and configured to emit a first light within a wavelength range of 380-420 nanometers (nm) and having a first intensity, and a second array of light emitters disposed on the second side and configured to emit a second light within the wavelength range of 380-420 nm and having a second intensity, wherein the first intensity comprises an intensity sufficient to initiate inactivation of micro-organisms, and wherein the first array of light emitters and the second array of light emitters are configured to collectively create a multi-dimensional space of disinfection.

Abstract: Methods, systems, and devices for inactivating microorganisms are disclosed. An example light emitting device that inactivates microorganisms on a surface comprises a light emitter configured to emit a first light comprising a first wavelength in a range of 380 nanometers (nm) to 420 nm, a first light-converting material configured to convert a first portion of the first light to at least a second light comprising a second wavelength different from the first wavelength, and a second light-converting material configured to convert a second portion of the first light to at least a third light comprising a third wavelength different from the first wavelength, wherein at least the first light, the second light, and the third light mix to form a disinfecting white light, wherein the first light makes up at least 10% of the disinfecting white light.

Abstract: Devices, methods, and systems for disinfection with light are disclosed. In some examples, a lighting source is operable to provide light at wavelength range of about 380 nm - 420 nm with an irradiance and/or dosage sufficient for disinfection. One or more sensors and a control system may be used to control operation of the lighting source, such as by adjusting the lighting source in response to various inputs.

Abstract: Systems and methods for bacterial load sensing devices are disclosed. An example contamination sensing device may comprise a body, a light emitter disposed on the body and configured to emit an excitation wavelength of light toward a surface, a sensor disposed on the body, configured to detect light, and directed toward the surface, and a filter adjuster configured to determine, based on the excitation wavelength of light, a filter configured to remove light outside of an emission wavelength range, wherein the emission wavelength range corresponds to wavelengths of light emitted by contamination upon exposure to the excitation wavelength of light, and adjustably move the filter in front of the sensor.

Abstract: Disclosed herein is a multiple light emitter device which inactivates microorganisms. The device includes at least two light emitters and at least one light-converting material arranged to convert at least a portion of light from the light emitters. Any unconverted light emitted from the light emitters and converted light emitted from the at least one light-converting material mixes to form a combined light, the combined light being white. In one aspect, the light emitters include at least one blue light emitter and at least one violet light emitter. In another aspect, the light emitters include one blue light emitter and one emitter within the range of approximately yellow to infrared light.

Abstract: Apparatuses, systems, and methods for combined light disinfection are disclosed. In some examples, a light fixture may comprise a first light source configured to emit a first light comprising a wavelength in a range of 380-420 nanometers (nm) and a second light source configured to emit a second light comprising a wavelength in a range of 200-230 nm, wherein the first light source and the second light source are separated to prevent degradation, by the second light, of the first light source, and wherein the first light and the second light combine to form a disinfecting light configured to initiate inactivation of microorganisms.