Abstract: The present invention relates to novel strains of pig that are highly suitable for xenotransplantation. The first novel pig strain lacks functional porcine endogenous retroviruses so is suitable as a donor for tissue and/or cell xenotransplantation into a human recipient. These pigs can also be used as a foundation pig for further manipulation, for example, by gene editing of xenoantigens to produce a second novel strain of pig that is not only free of infectious porcine retroviruses but is also free of the main xenoantigens responsible for hyperacute organ rejection. These pigs can be used for whole organ, tissue and/or cell transplantation into a human recipient.

Abstract: In combination with video content transmitted by a video streaming service, additional content may also be displayed to viewers. The video streaming service may provide a framework that allows the additional content to be provided by third parties. By allowing third parties to develop and provide additional content, the range of interactions and experiences made available through such content may, in some cases, be significantly expanded. The additional content may be displayed inside a respective assigned area, such as an inline frame (Iframe), embedded within a web page or other interface in which the video content is displayed. Additionally, techniques may be provided for controlling focus between a video player that displays the video content and the embedded area that displays the additional content, for example to help ensure that user input is provided to its intended target.

Abstract: A method for characterizing a FM chirp signal generated by a device under test (DUT) is disclosed. The method comprises receiving a selection of a sample frequency and chirp duration for capturing the FM chirp signal. The method also comprises down converting the FM chirp signal and capturing the FM chirp signal using a digital pin electronics card. The method comprises obtaining a plurality of period measurements from the captured FM chirp signal using a timing measurement unit (TMU) of an automated test equipment (ATE) and converting each of the plurality of period measurements into corresponding frequency values.

Abstract: An improved vehicle with superior performance and reliability. The vehicle, such as an unmanned aerial vehicle, is capable of vertical takeoff and landing, uses three swashless, variable-pitch vertical lift main rotors with a yaw tail rotor system. Two rear main rotors are optionally tiltrotors, which pivot to increase forward speed without the increased coefficient of drag inherent in tilting the entire vehicle. The three main rotors are positioned in an equilateral triangular configuration, improving balance, increasing load-bearing strength, and making it more compact in size. Movements are controlled through changes in pitch of the rotors, allowing the motors to maintain constant governed rotations per minute, maximizing drivetrain efficiency. Vehicle configurations disclosed herein allow for smaller vehicle size with greater performance than prior art vehicles.

Abstract: A method for characterizing a FM chirp signal generated by a device under test (DUT) is disclosed. The method comprises receiving a selection of a sample frequency and chirp duration for capturing the FM chirp signal. The method also comprises down converting the FM chirp signal and capturing the FM chirp signal using a digital pin electronics card. The method comprises obtaining a plurality of period measurements from the captured FM chirp signal using a timing measurement unit (TMU) of an automated test equipment (ATE) and converting each of the plurality of period measurements into corresponding frequency values.

Abstract: A vehicle with superior performance and reliability. The vehicle, such as an unmanned aerial vehicle, is capable of vertical takeoff and landing, uses three swashless, variable-pitch vertical lift main rotors with a yaw tail rotor system. Two rear main rotors are optionally tiltrotors, which pivot to increase forward speed without the increased coefficient of drag inherent in tilting the entire vehicle. The three main rotors are positioned in an equilateral triangular configuration, improving balance, increasing load-bearing strength, and making it more compact in size. Movements are controlled through changes in pitch of the rotors, allowing the motors to maintain constant governed rotations per minute, maximizing drivetrain efficiency. Various embodiments allow for smaller vehicle size with greater performance than prior art vehicles.

Abstract: A method for characterizing a FM chirp signal generated by a device under test (DUT) is disclosed. The method comprises receiving a selection of a sample frequency and chirp duration for capturing the FM chirp signal. The method also comprises down converting the FM chirp signal and capturing the FM chirp signal using a digital pin electronics card. The method comprises obtaining a plurality of period measurements from the captured FM chirp signal using a timing measurement unit (TMU) of an automated test equipment (ATE) and converting each of the plurality of period measurements into corresponding frequency values.

Abstract: A method of transmitting a fluid into an oil well bore including the steps of providing a frame supporting a vessel, the vessel having an interior, upper and lower end portions, a conically shaped side wall, and an outlet for discharging the fluid from the vessel. Further including the steps of adding a viscous polymeric material to the vessel interior, placing a discharge pipe having a vertical section below the vessel wherein the discharge pipe is in communication with the outlet, placing a positive displacement pump within the discharge pipe wherein the pump transmits fluid from the outlet into the discharge pipe downstream of the vertical pipe section, and selectively transmitting fluid to either the vessel interior (for recirculating) or into the well. Air is added to the discharge flow line downstream of the pump. Preferably, the vessel contains a flexible bladder/bag that holds the material to be pumped.

Abstract: An improved vehicle with superior performance and reliability. The vehicle, such as an unmanned aerial vehicle, is capable of vertical takeoff and landing, uses three swashless, variable-pitch vertical lift main rotors with a yaw tail rotor system. Two rear main rotors are optionally tiltrotors, which pivot to increase forward speed without the increased coefficient of drag inherent in tilting the entire vehicle. The three main rotors are positioned in an equilateral triangular configuration, improving balance, increasing load-bearing strength, and making it more compact in size. Movements are controlled through changes in pitch of the rotors, allowing the motors to maintain constant governed rotations per minute, maximizing drivetrain efficiency. Vehicle configurations disclosed herein allow for smaller vehicle size with greater performance than prior art vehicles.

Abstract: A method for characterizing a FM chirp signal generated by a device under test (DUT) is disclosed. The method comprises receiving a selection of a sample frequency and chirp duration for capturing the FM chirp signal. The method also comprises down converting the FM chirp signal and capturing the FM chirp signal using a digital pin electronics card. The method comprises obtaining a plurality of period measurements from the captured FM chirp signal using a timing measurement unit (TMU) of an automated test equipment (ATE) and converting each of the plurality of period measurements into corresponding frequency values.

Abstract: An interlock vessel having an air-tight body with opposing ends. A portion of the body is designed to fit into a decompression (hyperbaric) chamber, wherein a diver or a patient undergoing a decompression treatment is positioned. The opposing ends are closed by pivotally moveable doors and locking assemblies that retain the doors in a closed position until the pressure inside the decompression chamber and the exterior of the chamber can be equalized. The outer door has two locking systems: (a) an interlock system and (b) a safety/delay locking system. Both locking assemblies are manually operated.

Abstract: A fluids management apparatus is disclosed herein that enables management of multiple volumes of different fluids when drilling and/or producing oil and/or gas with an oil and gas well drilling platform. The apparatus includes a structural, transportable frame that has upper and lower reservoir sections, each with a plurality of tanks for holding fluid. The upper reservoir section is easily lifted and transported, such as by crane. A docking station on the lower reservoir section is receptive of the upper reservoir section. A piping system enables a selected fluid volume contained in a tank of the upper reservoir section to be selectively transmitted to a selected tank of the lower reservoir section. The lower reservoir section has its own piping system that enables a user to withdraw fluid from any selected one of its tanks.

Abstract: A fluids management apparatus is disclosed herein that enables management of multiple volumes of different fluids when drilling and/or producing oil and/or gas with an oil and gas well drilling platform. The apparatus includes a structural, transportable frame that has upper and lower reservoir sections, each with a plurality of tanks for holding fluid. The upper reservoir section is easily lifted and transported, such as by crane. A docking station on the lower reservoir section is receptive of the upper reservoir section. A piping system enables a selected fluid volume contained in a tank of the upper reservoir section to be selectively transmitted to a selected tank of the lower reservoir section. The lower reservoir section has its own piping system that enables a user to withdraw fluid from any selected one of its tanks.

Abstract: Disclosed are implant compositions and methods for treatment of neurological diseases of the central nervous system of a mammal.

Abstract: Milk-based products and drinks are provided including specified forms of identified proteins or fragments thereof, as are methods for the use of such milk-based products and drinks in the promotion of sleep.

Abstract: The invention relates to an improved method of culturing hepatocyte cells and non-hepatocyte cells that are capable of secreting liver secretory factors and their use in implantable compositions for treating liver diseases and disorders in patients in need thereof.

Abstract: A fluids management apparatus is disclosed herein that enables management of multiple volumes of different fluids when drilling and/or producing oil and/or gas with an oil and gas well drilling platform. The apparatus includes a structural, transportable frame that has upper and lower reservoir sections, each with a plurality of tanks for holding fluid. The upper reservoir section is easily lifted and transported, such as by crane. A docking station on the lower reservoir section is receptive of the upper reservoir section. A piping system enables a selected fluid volume contained in a tank of the upper reservoir section to be selectively transmitted to a selected tank of the lower reservoir section. The lower reservoir section has its own piping system that enables a user to withdraw fluid from any selected one of its tanks.

Abstract: A method of transmitting a fluid into an oil well bore provides a frame supporting a vessel, the vessel having an interior, upper and lower end portions, a conically shaped side wall, and an outlet for discharging the fluid from the vessel. A viscous polymeric material is added to the vessel interior. A discharge pipe having a vertical section is placed below the vessel, the discharge pipe being in communication with the outlet. A positive displacement pump is contained within the discharge pipe. The pump transmits fluid from the outlet into the discharge pipe downstream of the vertical pipe section or pump. The fluid is selectively transmitted to either the vessel interior (for recirculating) or into the well. Air is added to the discharge flow line downstream of the pump. In one embodiment, the vessel contains a flexible bladder or bag that holds the material to be pumped.

Abstract: The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon xenotransplantation of producing porcine insulin in an appropriate recipient mammal, the method including or comprising the steps of: (I) harvesting the pancreas of piglets at or near full term gestation, and (ii) extracting pancreatic ? islet cells from the harvested pancreas wherein the islets (at least at some stage in the performance of the method) are exposed to nicotinamide. Further, the invention relates to a method of encapsulation of a xenotransplantable porcine islet preparation, and transplantation of such a preparation, or a capsule containing such a preparation, into an appropriate recipient mammal.

Abstract: The present invention is directed to the use of choroid plexus cells and/or choroid plexus conditioned media for enhancing the growth, survival and/or maintenance of function of non-choroid plexus cells grown in long term or short term culture.