Patents by Inventor Robert Belas

Robert Belas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biosynthetic pathway and genes required for tropodithietic acid biosynthesis in silicibacter TM1040
    Patent number: 8058417
    Abstract: Production and use of a sulfur-containing compound, tropodithietic acid (TDA), from the roseobacter Silicibacter sp. TM1040 is described. Specifically, a biosynthetic and regulatory pathway for TDA biosynthesis in roseobacters is described. The TDA produced from roseobacters, specifically Silicibacter sp. TM1040, is shown to have antibacterial activity, in particular against Vibrio anguillarium, Vibrio cholerae, Vibrio coralliilyticus, Vibrio shiloi, Halomonas spp., Mycobacterium marinum, Mycobacterium tuberculosis, Pseudomonas elongate, Spongiobacter nikelotolerans, and Staphylococcus aureus (MRSA).
    Type: Grant
    Filed: May 26, 2009
    Date of Patent: November 15, 2011
    Inventors: Robert Belas, Haifeng Geng, Ryan Powell
  • BIOSYNTHETIC PATHWAY AND GENES REQUIRED FOR TROPODITHIETIC ACID BIOSYNTHESIS IN SILICIBACTER TM1040
    Publication number: 20100035960
    Abstract: Production and use of a sulfur-containing compound, tropodithietic acid (TDA), from the roseobacter Silicibacter sp. TM1040 is described. Specifically, a biosynthetic and regulatory pathway for TDA biosynthesis in roseobacters is described. The TDA produced from roseobacters, specifically Silicibacter sp. TM1040, is shown to have antibacterial activity, in particular against Vibrio anguillarium, Vibrio cholerae, Vibrio coralliilyticus, Vibrio shiloi, Halomonas spp., Mycobacterium marinum, Mycobacterium tuberculosis, Pseudomonas elongate, Spongiobacter nikelotolerans, and Staphylococcus aureus (MRSA).
    Type: Application
    Filed: May 26, 2009
    Publication date: February 11, 2010
    Applicant: UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE
    Inventors: Robert Belas, Haifeng Geng, Ryan Powell
  • SILICIBACTER SP. STRAIN USEFUL FOR GENETIC TRANSFORMATION OF MARINE ALGAE AND PRODUCTION OF ANTIBIOTIC AGENTS
    Publication number: 20090142429
    Abstract: A Silicibacter sp. strain useful for genetic transformation of marine algae and production of antibiotic agents is described. Silicibacter sp. TM1040 is a genetically tractable member of the marine Roseobacter clade of bacteria that forms an intimate and obligate interaction with algae, and is useful as a probiotic for producing antibacterial agents that are cidally effective against pathogenic bacteria such as Mycobacterium marinum, Vibrio anguillarum, V. coralliilyticus, and V. shiloi bacteria.
    Type: Application
    Filed: May 23, 2006
    Publication date: June 4, 2009
    Applicant: UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE
    Inventors: Robert Belas, Todd R. Miller, Jesper Bartholin Bruhn