Patents by Inventor Robert Ben

Robert Ben has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TERTIARY AMIDE ALDONAMIDE BASED ICE RECRYSTALLIZATION INHIBITOR COMPOUNDS AND COMPOSITIONS, AND USES THEREOF FOR CRYOPRESERVATION
    Publication number: 20260146239
    Abstract: The specification relates to a compound of formula (1), its enantiomer, diastereomer, or its physiologically acceptable salt thereof, along with a composition containing the same; wherein Q, J, R1, R2, R3, R4 and Ra are as disclosed herein. The compound or composition have potential for use as a cryopreservation agent or an ice crystal recrystallization inhibitor. In addition, disclosed is a method for cryopreserving a biological material. Further, disclosed is a process for preparation of the compound.
    Type: Application
    Filed: November 26, 2025
    Publication date: May 28, 2026
    Inventors: Robert Ben, André Paquette, Marcus Diamante
  • UREA-BASED ICE RECRYSTALLIZATION INHIBITOR COMPOUNDS AND COMPOSITIONS, AND USES THEREOF FOR CRYOPRESERVATION
    Publication number: 20260146238
    Abstract: The specification relates to a compound of formula (1), its enantiomer, diastereomer, or its physiologically acceptable salt thereof, along with a composition containing the same; wherein R1, R2, and R3 are as disclosed herein. The compound or composition have potential for use as a cryopreservation agent or an ice crystal recrystallization inhibitor. In addition, disclosed is a method for cryopreserving a biological material. Further, disclosed is a process for preparation of the compound.
    Type: Application
    Filed: November 26, 2025
    Publication date: May 28, 2026
    Inventors: Robert Ben, André Paquette
  • RADIOLABELED FRUCTOSE DERIVATIVES FOR MEDICAL IMAGING
    Publication number: 20260131033
    Abstract: There are provided fructose-based radiopharmaceuticals, pharmaceutical compositions comprising same, methods for preparing same, and methods of using same for biomedical imaging, particularly nuclear imaging using PET or PET/CT.
    Type: Application
    Filed: September 15, 2025
    Publication date: May 14, 2026
    Inventors: Adam Jason SHUHENDLER, Mojmir SUCHY, Robert BEN, Thomas CHARLTON, Alexia Margarite KIRBY, Nicholas David CALVERT
  • Small molecule ice recrystallization inhibitors and methods of use thereof
    Patent number: 10004222
    Abstract: Ice recrystallization inhibitor (IRI) compounds and methods for cryopreserving umbilical cord blood are provided. The compounds are unsubstituted, mono-substituted, or di-substituted aryl-aldonamides. The methods include fractionating whole umbilical cord blood to generate a fraction comprising hematopoietic stem cells, mixing the hematopoietic stem cells with at least one IRI compound to form an IRI suspension, and freezing the IRI suspension.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: June 26, 2018
    Assignee: THE UNIVERSITY OF OTTAWA
    Inventors: Robert Ben, Chantelle J. Capicciotti, Jennie Briard
  • Small molecule ice recrystallization inhibitors and methods of use thereof
    Patent number: 9648869
    Abstract: The invention relates to small molecule ice recrystallization inhibitor (IRI) compounds having increased ice recrystallization inhibition activity. The IRI compounds disclosed herein are useful in compositions, kits and methods for cryopreserving biological material such as organs, tissues and cells.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: May 16, 2017
    Assignee: THE UNIVERSITY OF OTTAWA
    Inventors: Robert Ben, Chantelle J. Capicciotti
  • Small Molecule Ice Recrystallization Inhibitors And Methods Of Use Thereof
    Publication number: 20150373968
    Abstract: Ice recrystallization inhibitor (IRI) compounds and methods for cryopreserving umbilical cord blood are provided. The compounds are unsubstituted, mono-substituted, or di-substituted aryl-adlonamides. The methods include fractionating whole umbilical cord blood to generate a fraction comprising hematopoietic stem cells, mixing the hematopoietic stem cells with at least one IRI compound to form an IRI suspension, and freezing the IRI suspension.
    Type: Application
    Filed: September 9, 2015
    Publication date: December 31, 2015
    Inventors: Robert BEN, Chantelle J. CAPICCIOTTI, Jennie Briard
  • SMALL MOLECULE ICE RECRYSTALLIZATION INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20150157010
    Abstract: The invention relates to small molecule ice recrystallization inhibitor (IRI) compounds having increased ice recrystallization inhibition activity. The IRI compounds disclosed herein are useful in compositions, kits and methods for cryopreserving biological material such as organs, tissues and cells.
    Type: Application
    Filed: May 24, 2013
    Publication date: June 11, 2015
    Inventors: Robert Ben, Chantelle J. Capicciotti