Abstract: POZ-lipid conjugates and lipid nanoparticles (LNPs) including POZ-lipid conjugates used to facilitate delivery of an encapsulated payload. LNPs including POZ-lipid conjugates and a nucleic acid payload such as, but not limited to, mRNA or modified mRNA are disclosed. Such LNPs have no immunogenicity or reduced immunogenicity as compared to a corresponding LNP containing a PEG-lipid.

Abstract: Low voltage LED filament array lighting in accordance with embodiments of the invention are illustrated. One embodiment includes a LED array light including a cover component with first and second faces and containing a control circuitry and a battery electrically coupled to the control circuitry, a solar panel in contact with the first face of the cover component and electrically coupled to the control circuitry, and an LED filament light bulb in contact with the second face of the cover component and electrically coupled to the control circuitry, wherein the LED filament light bulb comprises an array of LEDs and a fluorescent material, wherein the control circuitry routes electricity generated by the solar panel to the battery for storage when the solar panel is generating electricity, and wherein the control circuitry routes electricity from the battery to the LED filament light bulb when the solar panel is not generating electricity.

Abstract: A punch according to some embodiments of the disclosure includes a body having a punching edge and a wall forming a passageway therethrough, the wall having a multi-start thread formed thereon, and a draw stud according to some embodiments of the disclosure includes an elongated cylinder having a multi-start thread thereon which is configured to be coupled to the multi-start thread of the punch. The number of starts provided on the punch corresponds to the number of starts provided on the draw stud. The multi-start thread on the punch is engaged with the multi-start thread on the draw stud in use. A method using same to punch a hole in sheet metal is also provided.

Abstract: Low voltage LED filament array lighting in accordance with embodiments of the invention are illustrated. One embodiment includes a LED array light including a cover component with first and second faces and containing a control circuitry and a battery electrically coupled to the control circuitry, a solar panel in contact with the first face of the cover component and electrically coupled to the control circuitry, and an LED filament light bulb in contact with the second face of the cover component and electrically coupled to the control circuitry, wherein the LED filament light bulb comprises an array of LEDs and a fluorescent material, wherein the control circuitry routes electricity generated by the solar panel to the battery for storage when the solar panel is generating electricity, and wherein the control circuitry routes electricity from the battery to the LED filament light bulb when the solar panel is not generating electricity.

Abstract: A paint roller cover cleaner for cleaning a paint roller cover. The paint roller cover cleaner has one or more nozzles that spray the cover and that may each produce a fan-shaped jet in a plane that is at an angle to the longitudinal axis of the roller cover. The paint roller cover cleaner may also have a clamp for clamping a handle of the paint roller, another nozzle for cleaning an enclosure of the paint roller cover cleaner, a lid for the enclosure that drips within the mouth of the enclosure and does not move laterally across the roller cover to open. A system including a paint roller cover cleaner and a fluid supply that can contain the paint roller cover cleaner is also provided.

Abstract: Low voltage LED filament array lighting in accordance with embodiments of the invention are illustrated. One embodiment includes a LED array light including a cover component with first and second faces and containing a control circuitry and a battery electrically coupled to the control circuitry, a solar panel in contact with the first face of the cover component and electrically coupled to the control circuitry, and an LED filament light bulb in contact with the second face of the cover component and electrically coupled to the control circuitry, wherein the LED filament light bulb comprises an array of LEDs and a fluorescent material, wherein the control circuitry routes electricity generated by the solar panel to the battery for storage when the solar panel is generating electricity, and wherein the control circuitry routes electricity from the battery to the LED filament light bulb when the solar panel is not generating electricity.

Abstract: Low voltage LED filament array lighting in accordance with embodiments of the invention are illustrated. One embodiment includes a LED array light including a cover component with first and second faces and containing a control circuitry and a battery electrically coupled to the control circuitry, a solar panel in contact with the first face of the cover component and electrically coupled to the control circuitry, and an LED filament light bulb in contact with the second face of the cover component and electrically coupled to the control circuitry, wherein the LED filament light bulb comprises an array of LEDs and a fluorescent material, wherein the control circuitry routes electricity generated by the solar panel to the battery for storage when the solar panel is generating electricity, and wherein the control circuitry routes electricity from the battery to the LED filament light bulb when the solar panel is not generating electricity.

Abstract: A paint roller cover cleaner for cleaning a paint roller cover. The paint roller cover cleaner has one or more nozzles that spray the cover and that may each produce a fan-shaped jet in a plane that is at an angle to the longitudinal axis of the roller cover. The paint roller cover cleaner may also have a clamp for clamping a handle of the paint roller, another nozzle for cleaning an enclosure of the paint roller cover cleaner, a lid for the enclosure that drips within the mouth of the enclosure and does not move laterally across the roller cover to open. A system including a paint roller cover cleaner and a fluid supply that can contain the paint roller cover cleaner is also provided.

Abstract: A paint roller cover cleaner including an enclosure for a roller cover, a high pressure pump and a nozzle supplied with pressurised fluid which directs a jet of fluid at the nap of the roller cover to rotate the roller cover and facilitate cleaning. In one embodiment a carriage moves the nozzle along the length of the roller cover to effect cleaning along the length of the roller cover. In another embodiment a plurality of controllable nozzles are provided at intervals along the length of the roller cover. In another embodiment the nozzle includes an inner sleeve and an outer sleeve which relatively rotate to align apertures in the respective sleeves to produce jets sequentially along the nozzle.

Abstract: A paint roller cover cleaner including an enclosure for a roller cover, a high pressure pump and a nozzle supplied with pressurised fluid which directs a jet of fluid at the nap of the roller cover to rotate the roller cover and facilitate cleaning. In one embodiment a carriage moves the nozzle along the length of the roller cover to effect cleaning along the length of the roller cover. In another embodiment a plurality of controllable nozzles are provided at intervals along the length of the roller cover. In another embodiment the nozzle includes an inner sleeve and an outer sleeve which relatively rotate to align apertures in the respective sleeves to produce jets sequentially along the nozzle.

Abstract: Low voltage LED filament array lighting in accordance with embodiments of the invention are illustrated. One embodiment includes a LED array light including a cover component with first and second faces and containing a control circuitry and a battery electrically coupled to the control circuitry, a solar panel in contact with the first face of the cover component and electrically coupled to the control circuitry, and an LED filament light bulb in contact with the second face of the cover component and electrically coupled to the control circuitry, wherein the LED filament light bulb comprises an array of LEDs and a fluorescent material, wherein the control circuitry routes electricity generated by the solar panel to the battery for storage when the solar panel is generating electricity, and wherein the control circuitry routes electricity from the battery to the LED filament light bulb when the solar panel is not generating electricity.

Abstract: A hose for use in bio-pharmaceutical applications includes an innermost tubular layer made from a fluoropolymer material. The tubular layer has an inner, relatively smooth and pure surface that defines an opening for transfer of various media. A layer of silicone is disposed next to an outer surface of the innermost tubular layer through use of, for example, an extrusion method. The outer surface of the tubular layer may first be modified by various treatments or chemicals to facilitate the adhesion of the silicone layer thereto. The silicone material may be solid or foamed. A reinforcement layer may be disposed adjacent to an outer surface of the silicone layer. The reinforcement layer may be formed of a wire braid having gaps. An outer jacket of silicone may be attached to the reinforcement layer and to the inner silicone layer through the gaps in the reinforcement layer.

Abstract: A hose for use in bio-pharmaceutical applications includes an innermost tubular layer made from a fluoropolymer material. The tubular layer has an inner, relatively smooth and pure surface that defines an opening for transfer of various media. A layer of silicone is disposed next to an outer surface of the innermost tubular layer through use of, for example, an extrusion method. The outer surface of the tubular layer may first be modified by various treatments or chemicals to facilitate the adhesion of the silicone layer thereto. The silicone material may be solid or foamed. A reinforcement layer may be disposed adjacent to an outer surface of the silicone layer. The reinforcement layer may be formed of a wire braid having gaps. An outer jacket of silicone may be attached to the reinforcement layer and to the inner silicone layer through the gaps in the reinforcement layer.

Abstract: A hose for use in bio-pharmaceutical applications includes an innermost tubular layer made from a fluoropolymer material. The tubular layer has an inner, relatively smooth and pure surface that defines an opening for transfer of various media. A layer of silicone is disposed next to an outer surface of the innermost tubular layer through use of, for example, an extrusion method. The outer surface of the tubular layer may first be modified by various treatments or chemicals to facilitate the adhesion of the silicone layer thereto. The silicone material may be solid or foamed. A reinforcement layer may be disposed adjacent to an outer surface of the silicone layer. The reinforcement layer may be formed of a wire braid having gaps. An outer jacket of silicone may be attached to the reinforcement layer and to the inner silicone layer through the gaps in the reinforcement layer.

Abstract: A hose for use in bio-pharmaceutical applications includes an innermost tubular layer made from a fluoropolymer material. The tubular layer has an inner, relatively smooth and pure surface that defines an opening for transfer of various media. A layer of silicone is disposed next to an outer surface of the innermost tubular layer through use of, for example, an extrusion method. The outer surface of the tubular layer may first be modified by various treatments or chemicals to facilitate the adhesion of the silicone layer thereto. The silicone material may be solid or foamed. A reinforcement layer may be disposed adjacent to an outer surface of the silicone layer. The reinforcement layer may be formed of a wire braid having gaps. An outer jacket of silicone may be attached to the reinforcement layer and to the inner silicone layer through the gaps in the reinforcement layer.

Abstract: There is provided a hose assembly having a tubular first layer made up of a polymeric material resistant to chemical and heat degradation, a jacket disposed about the first layer, and at least one Aramid-like braided layer disposed between the first layer and the jacket. A method of making a hose assembly by forming a tubular first layer, disposing an Aramid-like braid about the first layer and extruding a jacket over the braid is also provided.