Patents by Inventor Robert Bonomo

Robert Bonomo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of treating of bacterial infections with ?-lactamase inhibitors
    Patent number: 10335425
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one triazolylmethyl boronic acid.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: July 2, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Robert Bonomo, Fabio Prati, Emilia Caselli, Chiara Romagnoli
  • Compositions and methods of inhibiting metallo-?-lactamases
    Patent number: 10251869
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one bisthiazolidine metallo-?-lactamase inhibitor.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: April 9, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Robert Bonomo, Alejandro Jose Vila, S. Graciela Mahler
  • COMPOSITIONS AND METHODS OF TREATING OF BACTERIAL INFECTIONS WITH BETA-LACTAMASE INHIBITORS
    Publication number: 20180256614
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one triazolylmethyl boronic acid.
    Type: Application
    Filed: April 24, 2018
    Publication date: September 13, 2018
    Inventors: Robert Bonomo, Fabio Prati, Emilia Caselli, Chiara Romagnoli
  • Compositions and methods of treating of bacterial infections with ?-lactamase inhibitors
    Patent number: 9949995
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one triazolylmethyl boronic acid.
    Type: Grant
    Filed: September 6, 2016
    Date of Patent: April 24, 2018
    Assignee: Case Western Reserve University
    Inventors: Robert Bonomo, Fabio Prati, Emilia Caselli, Chiara Romagnoli
  • COMPOSITIONS AND METHODS OF INHIBITING METALLO-BETA-LACTAMASES
    Publication number: 20170252326
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one bisthiazolidine metallo-?-lactamase inhibitor.
    Type: Application
    Filed: March 20, 2017
    Publication date: September 7, 2017
    Inventors: Robert Bonomo, Alejandro Jose Vila, James Spencer, S. Graciela Mahler
  • Compositions and methods of inhibiting metallo-?-lactamases
    Patent number: 9597319
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one bisthiazolidine metallo-?-lactamase inihibitor.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: March 21, 2017
    Assignee: Case Western Reserve University
    Inventors: Robert Bonomo, S. Graciela Mahler
  • COMPOSITIONS AND METHODS OF TREATING OF BACTERIAL INFECTIONS WITH BETA-LACTAMASE INHIBITORS
    Publication number: 20170065626
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one triazolylmethyl boronic acid.
    Type: Application
    Filed: September 6, 2016
    Publication date: March 9, 2017
    Inventors: Robert Bonomo, Fabio Prati, Emilia Caselli, Chiara Romagnoli
  • COMPOSITIONS AND METHODS OF INHIBITING METALLO-B-LACTAMASES
    Publication number: 20150306075
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one bisthiazolidine metallo-?-lactamase inihibitor.
    Type: Application
    Filed: April 23, 2015
    Publication date: October 29, 2015
    Inventors: Robert Bonomo, S. Graciela Mahler