Patents by Inventor Robert Boock
Robert Boock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240000352Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.Type: ApplicationFiled: June 30, 2023Publication date: January 4, 2024Inventors: Robert Boock, Monica Rixman Swinney, Huashi Zhang, Michael J. Estes, Kristina Lawrence
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Publication number: 20230380736Abstract: Disclosed herein are devices, systems, and methods for a continuous analyte sensor, such as a continuous glucose sensor. In certain embodiments disclosed herein, various in vivo properties of the sensor's surroundings can be measured. In some embodiments, the measured properties can be used to identify a physiological response or condition in the body. This information can then be used by a patient, doctor, or system to respond appropriately to the identified condition.Type: ApplicationFiled: June 2, 2023Publication date: November 30, 2023Inventors: Naresh C. Bhavaraju, Sebastian Böhm, Robert Boock, Daiting Rong, Peter C. Simpson
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Publication number: 20230301563Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.Type: ApplicationFiled: March 13, 2023Publication date: September 28, 2023Inventors: Peter C. Simpson, Robert Boock, Paul V Neale, Sebastian Bohm, Matthew D. Wightlin, Jack Pryor, Jason Mitchell, Jeff Jackson, Kaushik Patel, Antonio C. Lievares
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Patent number: 11730407Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.Type: GrantFiled: January 24, 2022Date of Patent: August 22, 2023Assignee: Dexcom, Inc.Inventors: Robert Boock, Monica Rixman Swinney, Huashi Zhang, Michael J. Estes, Kristina Lawrence
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Publication number: 20230165534Abstract: Systems and methods for detecting noise episodes and processing analyte sensor data responsive thereto. In some embodiments, processing analyte sensor data includes filtering the sensor data to reduce or eliminate the effects of the noise episode on the signal.Type: ApplicationFiled: September 2, 2022Publication date: June 1, 2023Inventors: Apurv U. Kamath, Aarthi Mahalingam, Ying Li, Mohammad Shariati, James H. Brauker, Mark C. Brister, Robert Boock
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Publication number: 20220346674Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice.Type: ApplicationFiled: July 18, 2022Publication date: November 3, 2022Applicant: DexCom, Inc.Inventors: Robert Boock, Jeff Jackson, Huashi Zhang, Jason Mitchell
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Publication number: 20220331491Abstract: A composite implant is provided for repairing a tissue defect in a patient. In one embodiment, the implant is a porous tissue scaffold having at least one pocket formed therein and adapted to contain a viable tissue. The tissue scaffold can have a variety of configurations, and in one embodiment it includes top and bottom portions that can be at least partially mated to one another, and in an exemplary embodiment that are heated sealed to one another around a perimeter thereof to form an enclosed pocket therebetween. The pocket is preferably sealed with a viable tissue disposed therein. In another embodiment, the tissue scaffold is substantially wedge-shaped and the pocket comprises a hollow interior formed in the tissue scaffold, and/or at least one lumen extending into the tissue scaffold. The tissue scaffold can also optionally include at least one surface feature formed thereof to promote blood vessel formation.Type: ApplicationFiled: June 30, 2022Publication date: October 20, 2022Inventors: Stephanie M. Kladakis, Sridevi Dhanaraj, Robert Boock
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Patent number: 11432772Abstract: Systems and methods for detecting noise episodes and processing analyte sensor data responsive thereto. In some embodiments, processing analyte sensor data includes filtering the sensor data to reduce or eliminate the effects of the noise episode on the signal.Type: GrantFiled: June 5, 2018Date of Patent: September 6, 2022Assignee: Dexcom, Inc.Inventors: Apurv Ullas Kamath, Aarthi Mahalingam, Ying Li, Mohammad Ali Shariati, James H. Brauker, Mark C. Brister, Robert Boock
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Patent number: 11395865Abstract: A composite implant is provided for repairing a tissue defect in a patient. In one embodiment, the implant is a porous tissue scaffold having at least one pocket formed therein and adapted to contain a viable tissue. The tissue scaffold can have a variety of configurations, and in one embodiment it includes top and bottom portions that can be at least partially mated to one another, and in an exemplary embodiment that are heated sealed to one another around a perimeter thereof to form an enclosed pocket therebetween. The pocket is preferably sealed with a viable tissue disposed therein. In another embodiment, the tissue scaffold is substantially wedge-shaped and the pocket comprises a hollow interior formed in the tissue scaffold, and/or at least one lumen extending into the tissue scaffold. The tissue scaffold can also optionally include at least one surface feature formed thereof to promote blood vessel formation.Type: GrantFiled: February 9, 2004Date of Patent: July 26, 2022Assignee: DePuy Synthes Products, Inc.Inventors: Stephanie M. Kladakis, Sridevi Dhanaraj, Robert Boock
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Publication number: 20220211301Abstract: In some embodiments, an electrochemical sensing system includes a working electrode and a reference electrode. At least a portion of the working electrode includes rhodium. An electrical circuit is electronically coupled to the working electrode and the reference electrode. The electrical circuit is configured to bias the working electrode at voltage of less than about 0.4 V which is sufficient to electrochemically decompose a target analyte, and to measure a current corresponding to the concentration of the target analyte. In some embodiments, a biosensing molecule can be disposed on the working electrode and is operative to catalytically decompose a non-electroactive target analyte to yield and an electroactive by-product. In some embodiment, the reference electrode can include rhodium and its oxides.Type: ApplicationFiled: January 18, 2022Publication date: July 7, 2022Applicant: Glucovation, Inc.Inventors: Jeff T. Suri, Robert Boock
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Publication number: 20220142532Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.Type: ApplicationFiled: January 24, 2022Publication date: May 12, 2022Inventors: Robert Boock, Monica Rixman Swinney, Huashi Zhang, Michael J. Estes, Kristina Lawrence
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Patent number: 11259724Abstract: In some embodiments, an electrochemical sensing system includes a working electrode and a reference electrode. At least a portion of the working electrode includes rhodium. An electrical circuit is electronically coupled to the working electrode and the reference electrode. The electrical circuit is configured to bias the working electrode at voltage of less than about 0.4 V which is sufficient to electrochemically decompose a target analyte, and to measure a current corresponding to the concentration of the target analyte. In some embodiments, a biosensing molecule can be disposed on the working electrode and is operative to catalytically decompose a non-electroactive target analyte to yield and an electroactive by-product. In some embodiment, the reference electrode can include rhodium and its oxides.Type: GrantFiled: March 12, 2015Date of Patent: March 1, 2022Inventors: Jeff T. Suri, Robert Boock
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Publication number: 20190307371Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice.Type: ApplicationFiled: June 25, 2019Publication date: October 10, 2019Inventors: Robert Boock, Jeff Jackson, Huashi Zhang, Jason Mitchell
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Publication number: 20180289333Abstract: Systems and methods for detecting noise episodes and processing analyte sensor data responsive thereto. In some embodiments, processing analyte sensor data includes filtering the sensor data to reduce or eliminate the effects of the noise episode on the signal.Type: ApplicationFiled: June 5, 2018Publication date: October 11, 2018Inventors: Apurv Ullas Kamath, Aarthi Mahalingam, Ying Li, Mohammad Ali Shariati, James H. Brauker, Mark C. Brister, Robert Boock
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Patent number: 10085737Abstract: A suture anchor is provided including an elongate shank defining a longitudinal axis and having at least one bone-engaging thread formed thereon, and a drive head having a proximal end and a distal end mated to the elongate shank. The drive head has a substantially oval shape and includes at least one suture attachment member formed in a portion of the drive head. The configuration of the drive head is particularly advantages in that it provides a suture anchor having improved physical properties, including a high failure torque and a high stripping strength.Type: GrantFiled: October 29, 2015Date of Patent: October 2, 2018Assignee: DEPUY MITEK, LLCInventors: Robert Boock, Nathan S. Cauldwell
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Patent number: 10022078Abstract: The present invention relates generally to biointerface membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel biointerface membranes, to devices and implantable devices including these membranes, methods for forming the biointerface membranes on or around the implantable devices, and to methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device.Type: GrantFiled: May 23, 2006Date of Patent: July 17, 2018Assignee: DexCom, Inc.Inventors: James H. Brauker, Peter C. Simpson, Robert Boock, Monica Rixman, Mark Brister
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Patent number: 9986942Abstract: Biointerface membranes are provided which can be utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device incorporating such membranes are provided.Type: GrantFiled: August 10, 2006Date of Patent: June 5, 2018Assignee: DexCom, Inc.Inventors: James H. Brauker, Robert Boock, Monica Rixman, Peter C. Simpson, Mark Brister, Mark Shults
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Publication number: 20170273610Abstract: An electrochemical sensing system includes a working electrode and a reference electrode, which can at least partially be disposed in a housing. At least a portion of the working electrode includes rhodium metal. An electrical circuit is disposed in the housing and configured to be electronically coupled to the electrodes. The electrical circuit is operative to: (a) bias the working electrode at a voltage of less than about 0.4 V, and (b) measure a current corresponding to the concentration of the target analyte. A communications module is electrically coupled to the electrical circuit and configured to display a concentration of the target analyte, and/or communicate data between the electrical circuit and an external device. The electrodes are movable between a first configuration in which the electrodes are substantially disposed inside the housing, and a second configuration in which at least a portion of the electrodes is disposed outside the housing.Type: ApplicationFiled: March 12, 2015Publication date: September 28, 2017Inventors: Jeff T. Suri, Robert Boock, Kenneth San Vicente
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Publication number: 20170273603Abstract: In some embodiments, an electrochemical sensing system includes a working electrode and a reference electrode. At least a portion of the working electrode includes rhodium. An electrical circuit is electronically coupled to the working electrode and the reference electrode. The electrical circuit is configured to bias the working electrode at voltage of less than about 0.4 V which is sufficient to electrochemically decompose a target analyte, and to measure a current corresponding to the concentration of the target analyte. In some embodiments, a biosensing molecule can be disposed on the working electrode and is operative to catalytically decompose a non-electroactive target analyte to yield and an electroactive by-product. In some embodiment, the reference electrode can include rhodium and its oxides.Type: ApplicationFiled: March 12, 2015Publication date: September 28, 2017Applicant: GLUCOVATION, INC.Inventors: Jeff T. Suri, Robert Boock
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Patent number: 9763608Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.Type: GrantFiled: December 4, 2015Date of Patent: September 19, 2017Assignee: DexCom, Inc.Inventors: Peter C. Simpson, Robert Boock, Paul V. Neale, Sebastian Böhm, Matthew Wightlin, Jack Pryor, Jason Mitchell, Jeff Jackson, Kaushik Patel, Antonio C. Llevares