Patents by Inventor Robert Bratzler

Robert Bratzler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunostimulatory nucleic acids for the treatment of asthma and allergy
    Publication number: 20070037767
    Abstract: The invention involves administration of an immunostimulatory nucleic acid alone or in combination with an asthma/allergy medicament for the treatment or prevention of asthma and allergy in subjects. The combination of drugs are administered in synergistic amounts or in various dosages or at various time schedules. The invention also relates to kits and compositions concerning the combination of drugs.
    Type: Application
    Filed: September 22, 2006
    Publication date: February 15, 2007
    Applicant: Coley Pharmaceutical Group, Inc.
    Inventors: Robert Bratzler, Deanna Petersen, Yves Fouron
  • Methods related to immunostimulatory nucleic acid-induced interferon
    Publication number: 20060286070
    Abstract: Methods and compositions are provided for extending the clinical utility of IFN-? in the treatment of a variety of viral and proliferative disorders. Among other aspects, the invention provides methods which increase the efficacy of IFN-? treatment and reduce IFN-? treatment-related side effects. In addition, methods are provided for supporting the survival and for activating natural interferon producing cells (IPCs) in vitro without exogenous IL-3 or GM-CSF. The invention is based on the discovery that certain CpG and non-CpG ISNAs promote survival and stimulation of IPCs.
    Type: Application
    Filed: July 8, 2005
    Publication date: December 21, 2006
    Applicants: Coley Pharmaceutical GmbH, Coley Pharmaceutical Group, Inc., University of Iowa Research Foundation
    Inventors: Gunther Hartmann, Robert Bratzler, Arthur Krieg
  • Immunostimulatory nucleic acids and cancer medicament combination therapy for the treatment of cancer
    Publication number: 20060211639
    Abstract: The invention involves administration of an immunostimulatory nucleic acid in combination with a cancer medicament for the treatment or prevention of cancer in subjects. The combination of drugs are administered in synergistic amounts or in various dosages or at various time schedules. The invention also relates to kits and compositions concerning the combination of drugs.
    Type: Application
    Filed: September 22, 2003
    Publication date: September 21, 2006
    Inventors: Robert Bratzler, Deanna Petersen
  • Methods and products for enhancing immune responses using imidazoquinoline compounds
    Publication number: 20060188913
    Abstract: The invention involves administration of an imidazoquinoline agent in combination with another therapeutic agent. The combination of drugs may be administered in synergistic amounts or in various dosages or at various time schedules. The invention also relates to kits and compositions concerning the combination of drugs. The combinations can be used to enhance ADCC, stimulate immune responses and/or patient and treat certain disorders.
    Type: Application
    Filed: March 3, 2006
    Publication date: August 24, 2006
    Applicants: University of Iowa Research Foundation, Coley Pharmaceutical GmbH, Coley Pharmaceutical Group, Inc.
    Inventors: Arthur Krieg, Christian Schetter, Robert Bratzler, Jorg Vollmer, Marion Jurk, Stefan Bauer
  • Immunostimulatory nucleic acids for the treatment of asthma and allergy
    Publication number: 20060154890
    Abstract: The invention involves administration of an immunostimulatory nucleic acid alone or in combination with an asthma/allergy medicament for the treatment or prevention of asthma and allergy in subjects. The combination of drugs are administered in synergistic amounts or in various dosages or at various time schedules. The invention also relates to kits and compositions concerning the combination of drugs.
    Type: Application
    Filed: December 9, 2005
    Publication date: July 13, 2006
    Applicant: Coley Pharmaceutical Group, Inc.
    Inventors: Robert Bratzler, Deanna Petersen, Yves Fouron
  • Methods related to immunostimulatory nucleic acid-induced interferon
    Publication number: 20050169888
    Abstract: Methods and compositions are provided for extending the clinical utility of IFN-? in the treatment of a variety of viral and proliferative disorders. Among other aspects, the invention provides methods which increase the efficacy of IFN-? treatment and reduce IFN-? treatment-related side effects. In addition, methods are provided for supporting the survival and for activating natural interferon producing cells (IPCs) in vitro without exogenous IL-3 or GM-CSF. The invention is based on the discovery that certain CpG and non-CpG ISNAs promote survival and stimulation of IPCs.
    Type: Application
    Filed: February 11, 2005
    Publication date: August 4, 2005
    Applicants: Coley Pharmaceutical GmbH, Coley Pharmaceutical Group, Inc., University of Iowa Research Foundation
    Inventors: Gunther Hartmann, Robert Bratzler, Arthur Krieg