Patents by Inventor Robert Brigance

Robert Brigance has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
    Patent number: 7635699
    Abstract: Compounds are provided having the formula (I) wherein X for each occurrence is N or C-A, and R, Y, A and n are as defined herein, which compounds are dipeptidyl peptidase IV inhibitors and as such are useful in treating diabetes and micro- and macrovascular complications of diabetes, such as retinopathy, neuropathy, and nephropathy. A method for treating diabetes and related diseases employing the above compounds is also provided.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: December 22, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Wei Meng, Lawrence G. Hamann, Robert Brigance
  • Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
    Patent number: 7589088
    Abstract: Compounds are provided having the formula (I) wherein R, B, X and Y are as defined herein.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: September 15, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Wei Meng, Lawrence G. Hamann, Robert Brigance
  • Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
    Publication number: 20060178377
    Abstract: Compounds are provided having the formula (I) wherein R, X, Y, A and n are as defined herein.
    Type: Application
    Filed: December 21, 2005
    Publication date: August 10, 2006
    Inventors: Wei Meng, Lawrence Hamann, Robert Brigance
  • Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
    Publication number: 20060142576
    Abstract: Compounds are provided having the formula (I) wherein R, B, X and Y are as defined herein.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 29, 2006
    Inventors: Wei Meng, Lawrence Hamann, Robert Brigance
  • Process for the preparation of unsymmetrical 4,6-bis(aryloxy) pyrimidine compounds
    Patent number: 6087498
    Abstract: There is provided a process for the preparation of unsymmetrical 4,6-bis(aryloxy)pyrimidine compounds. The unsymmetrical 4,6-bis(aryloxy)pyrimidine compounds are useful as pesticidal agents.
    Type: Grant
    Filed: March 16, 1999
    Date of Patent: July 11, 2000
    Assignee: American Cyanamid Company
    Inventors: William Wakefield Wood, Salvatore John Cuccia, Robert Brigance
  • Process for the preparation of unsymmetrical 4,6-bis(aryloxy) pyrimidine compounds
    Patent number: 5977363
    Abstract: There is provided a process for the preparation of unsymmetrical 4,6-bis(aryloxy)pyrimidine compounds. The unsymmetrical 4,6-bis(aryloxy)pyrimidine compounds are useful as pesticidal agents.
    Type: Grant
    Filed: May 12, 1998
    Date of Patent: November 2, 1999
    Assignee: American Cyanamid Company
    Inventors: William Wakefield Wood, Salvatore John Cuccia, Robert Brigance