Abstract: A portable dual chamber auto-injector configured to store a dry opioid antagonist medicament separately from a liquid component, wherein a user actuated mixing system comprising a movable component to create a fluidic pathway between the first and second chambers and release a portion of energy from a pre-stored energy to drive a displacement mechanism into the first chamber and displace the liquid component into the second chamber and solubilize the opioid antagonist. A needle assembly in fluid communication with the second chamber can be used to transfer the solubilized opioid antagonist.

Abstract: Sensor-enabled surgical retractor devices, systems, and methods are disclosed herein that can be coupled to a surgical robot during a robotic or robot-assisted surgical procedure to maintain health of retracted anatomy and prolong the amount of time until a surgical procedure must be interrupted to adjust a retractor. In some embodiments, interruption of a surgical procedure can be avoided by providing for minor and, in some cases, automatically administered, adjustment of retractor devices to alleviate pressure on retracted tissue without requiring surgeon attention or intervention. Fine (e.g., minor) adjustments to the retractor can be made automatically over the course of a surgical procedure to prevent damage to retracted anatomy and increase the time until a major adjustment of the retractor is needed.

Abstract: Techniques for wound image processing are disclosed. Access to a smartphone that includes an integrated color camera is obtained. An external light source is coupled to the smartphone. The external light source emits at least one light wavelength for illuminating a material sample. The light wavelength excites a fluorescence response from the sample. The fluorescence response comprises wavelengths along the Red-Green-Blue (RGB) light spectrum. The external light source is triggered. An illumination signature of the sample is captured, by the integrated color camera, in response to the external light. An output indicative of biophysical status of the sample is generated. The output is based on analysis of the captured illumination signature. A thermal image of the sample is further captured, using an infrared sensor coupled to the external light source. The output is augmented based on an analysis of the thermal image.

Abstract: Systems, methods, and instruments for tracking localized movement of an anatomic structure at a surgical site are provided that can, for example, detect and identify movement of the anatomic structure not otherwise tracked by a global navigation system. One embodiment can include a cannula with a localized navigation sensor coupled to a distal end thereof. The cannula can be coupled to a robot arm and the localized navigation sensor can detect movement of an anatomic structure relative to the cannula. The localized navigation sensor can include one or more tines that selectively extend from the cannula to contact the anatomic structure. A controller can receive data from the localized navigation sensor and a global navigation system, and determine if movement detected by the localized navigation sensor is tracked by the global navigation system. Systems, methods, and instruments of the present disclosure can be used independently of a global navigation system.

Abstract: Systems, methods, and instruments for tracking localized movement of an anatomic structure at a surgical site are provided that can, for example, detect and identify movement of the anatomic structure not otherwise tracked by a global navigation system. One embodiment can include a cannula with a localized navigation sensor coupled to a distal end thereof. The cannula can be coupled to a robot arm and the localized navigation sensor can detect movement of an anatomic structure relative to the cannula. The localized navigation sensor can include one or more tines that selectively extend from the cannula to contact the anatomic structure. A controller can receive data from the localized navigation sensor and a global navigation system, and determine if movement detected by the localized navigation sensor is tracked by the global navigation system. Systems, methods, and instruments of the present disclosure can be used independently of a global navigation system.

Abstract: A portable dual chamber auto-injector configured to store a dry opioid antagonist medicament separately from a liquid component, wherein a user actuated mixing system comprising a movable component to create a fluidic pathway between the first and second chambers and release a portion of energy from a pre-stored energy to drive a displacement mechanism into the first chamber and displace the liquid component into the second chamber and solubilize the opioid antagonist. A needle assembly in fluid communication with the second chamber can be used to transfer the solubilized opioid antagonist.

Abstract: Systems, methods, and instruments for tracking localized movement of an anatomic structure at a surgical site are provided that can, for example, detect and identify movement of the anatomic structure not otherwise tracked by a global navigation system. One embodiment can include a cannula with a localized navigation sensor coupled to a distal end thereof. The cannula can be coupled to a robot arm and the localized navigation sensor can detect movement of an anatomic structure relative to the cannula. The localized navigation sensor can include one or more tines that selectively extend from the cannula to contact the anatomic structure. A controller can receive data from the localized navigation sensor and a global navigation system, and determine if movement detected by the localized navigation sensor is tracked by the global navigation system. Systems, methods, and instruments of the present disclosure can be used independently of a global navigation system.

Abstract: Surgical systems and methods are disclosed, including, in one embodiment, a system having a coupling system disposed on a distal end portion of a surgical robot arm that secures a navigation array to the robot arm in a plurality of different orientations. The system further includes a navigation system configured to determine a precise location of the distal end portion by measuring a precise location of the navigation array by visually observing the navigation array, receiving a location of the coupling system via one or more encoders in the robot arm, determining the orientation of the navigation array relative to the robot arm based on the visual observation of the navigation array and the received location of the coupling system, and determining the precise location of the distal end portion of the surgical robot arm based on a known spatial relationship between the distal end portion and the coupling system.

Abstract: Sensor-enabled surgical retractor devices, systems, and methods are disclosed herein that can be coupled to a surgical robot during a robotic or robot-assisted surgical procedure to maintain health of retracted anatomy and prolong the amount of time until a surgical procedure must be interrupted to adjust a retractor. In some embodiments, interruption of a surgical procedure can be avoided by providing for minor and, in some cases, automatically administered, adjustment of retractor devices to alleviate pressure on retracted tissue without requiring surgeon attention or intervention. Fine (e.g., minor) adjustments to the retractor can be made automatically over the course of a surgical procedure to prevent damage to retracted anatomy and increase the time until a major adjustment of the retractor is needed.

Abstract: Sterile connectors for robotic or robot-assisted surgery and related systems and methods can be used to establish a sterile barrier between a non-sterile robot arm and a surgical site. More particularly, a sterile connector can include a first component connector to couple to a distal end of a robot arm, a second component connector to couple to an end effector, and a sterile drape extending from the sterile connector. The sterile drape can drape the robot arm and can maintain a sterile barrier around the robot arm throughout the course of a surgical procedure. In this manner, an end effector can be swapped out during the procedure without the need to re-drape or re-establish the sterile surgical field. In some embodiments, the sterile connector can facilitate the passage of electrical signals and/or light between the sterile connector and at least one of the robot arm and end effector.

Abstract: Systems, methods, and devices are disclosed for surgical instruments, systems, and methods for preventing skiving of a drilling instrument during a robotic or robot-assisted surgery are disclosed. In one embodiment, a scan of a patient's anatomy can be performed to produce a model of the bone to be drilled into and analysis of the surface can determine if the curvature is such that, if a target trajectory for a bore were followed, skiving of the drilling instrument is likely. If so, an alternate anti-skiving trajectory can be determined. The anti-skiving trajectory of a bore differs from the target trajectory by at least one of entry point, diameter, axis, or depth.

Abstract: Sensor-enabled surgical retractor devices, systems, and methods are disclosed herein that can be coupled to a surgical robot during a robotic or robot-assisted surgical procedure to maintain health of retracted anatomy and prolong the amount of time until a surgical procedure must be interrupted to adjust a retractor. In some embodiments, interruption of a surgical procedure can be avoided by providing for minor and, in some cases, automatically administered, adjustment of retractor devices to alleviate pressure on retracted tissue without requiring surgeon attention or intervention. Fine (e.g., minor) adjustments to the retractor can be made automatically over the course of a surgical procedure to prevent damage to retracted anatomy and increase the time until a major adjustment of the retractor is needed.

Abstract: Sterile connectors for robotic or robot-assisted surgery and related systems and methods can be used to establish a sterile barrier between a non-sterile robot arm and a surgical site. More particularly, a sterile connector can include a first component connector to couple to a distal end of a robot arm, a second component connector to couple to an end effector, and a sterile drape extending from the sterile connector. The sterile drape can drape the robot arm and can maintain a sterile barrier around the robot arm throughout the course of a surgical procedure. In this manner, an end effector can be swapped out during the procedure without the need to re-drape or re-establish the sterile surgical field. In some embodiments, the sterile connector can facilitate the passage of electrical signals and/or light between the sterile connector and at least one of the robot arm and end effector.

Abstract: Systems, methods, and devices are disclosed for surgical instruments, systems, and methods for preventing skiving of a drilling instrument during a robotic or robot-assisted surgery are disclosed. In one embodiment, a scan of a patient's anatomy can be performed to produce a model of the bone to be drilled into and analysis of the surface can determine if the curvature is such that, if a target trajectory for a bore were followed, skiving of the drilling instrument is likely. If so, an alternate anti-skiving trajectory can be determined. The anti-skiving trajectory of a bore differs from the target trajectory by at least one of entry point, diameter, axis, or depth.

Abstract: Systems, methods, and devices are disclosed for end effector identification in robotic surgical systems. A surgical robot can be coupled to an end effector. The system can identify the end effector using data received from the end effector. The system can adjust operation of the surgical system, including the robot arm, based on the data received from the end effector. Data received from or regarding the end effector can include detected characteristics, retrieved characteristics, or data stored on the end effector and communicated to the system. Both the identification and the operation adjustments can be performed automatically such that the system experiences little to no lag or downtime when coupling with different end effectors.

Abstract: Systems, methods, and devices are disclosed for surgical instruments, systems, and methods for detecting skiving of a surgical instrument, such as an instrument used during a robotic or robot-assisted surgery. The embodiments disclosed herein may include one or more sensors adjacent to, coupled to, disposed on, or embedded into an instrument in order to measure deflection thereof during use that may indicate skiving of the instrument. A variety of sensors may be utilized, including strain gauges, resistance-based sensors, fiber optic cables, laser distance measurement units, ultrasonic distance measurement units, optical cable measurement units, etc. In some embodiments, multiple such sensors may be included in an instrument in order to measure magnitude and/or direction of deflection.

Abstract: Systems, methods, and instruments for tracking localized movement of an anatomic structure at a surgical site are provided that can, for example, detect and identify movement of the anatomic structure not otherwise tracked by a global navigation system. One embodiment can include a cannula with a localized navigation sensor coupled to a distal end thereof. The cannula can be coupled to a robot arm and the localized navigation sensor can detect movement of an anatomic structure relative to the cannula. The localized navigation sensor can include one or more tines that selectively extend from the cannula to contact the anatomic structure. A controller can receive data from the localized navigation sensor and a global navigation system, and determine if movement detected by the localized navigation sensor is tracked by the global navigation system. Systems, methods, and instruments of the present disclosure can be used independently of a global navigation system.

Abstract: Sensor-enabled surgical retractor devices, systems, and methods are disclosed herein that can be coupled to a surgical robot during a robotic or robot-assisted surgical procedure to maintain health of retracted anatomy and prolong the amount of time until a surgical procedure must be interrupted to adjust a retractor. In some embodiments, interruption of a surgical procedure can be avoided by providing for minor and, in some cases, automatically administered, adjustment of retractor devices to alleviate pressure on retracted tissue without requiring surgeon attention or intervention. Fine (e.g., minor) adjustments to the retractor can be made automatically over the course of a surgical procedure to prevent damage to retracted anatomy and increase the time until a major adjustment of the retractor is needed.

Abstract: Disclosed herein are apparatuses, kits, and methods for treating skin, such as skin tightening, e.g., reducing skin laxity, for treating conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, and/or skin repositioning, and/or for generally improving skin function or appearance. Such apparatuses, kits, and methods include one or more hollow needles each having at least one prong and a mechanism for removing skin tissue portion(s) from the hollow needle(s).

Abstract: Sensor-enabled surgical retractor devices, systems, and methods are disclosed herein that can be coupled to a surgical robot during a robotic or robot-assisted surgical procedure to maintain health of retracted anatomy and prolong the amount of time until a surgical procedure must be interrupted to adjust a retractor. In some embodiments, interruption of a surgical procedure can be avoided by providing for minor and, in some cases, automatically administered, adjustment of retractor devices to alleviate pressure on retracted tissue without requiring surgeon attention or intervention. Fine (e.g., minor) adjustments to the retractor can be made automatically over the course of a surgical procedure to prevent damage to retracted anatomy and increase the time until a major adjustment of the retractor is needed.