Abstract: The present disclosure relates to methods of generating antibodies with improved specificity and/or affinity for a target antigen, as well as B-cells and hybridomas expressing the antibodies and compositions comprising antibodies with improved specificity and/or affinity for the target antigen.

Abstract: Communications equipment can be tested using a test pattern that is modified compared to, and more exploitive than, a standard test pattern. Test patterns can be employed that have lengthened or shortened consecutive identical digit (CID) portions, or that have lengthened or shortened pseudo random bit sequence (PRBS) portions. In some cases, PRBS polynomials are not re-seeded after each CID. Further, different order polynomials can be employed for different applications. Exemplary applications can include test equipment and built-in self-test capability for integrated circuits.

Abstract: Communications equipment can be tested using a test pattern encapsulated within a frame, and offsetting the test pattern in each successive frame. In equipment having a number of data latches receiving serial input, the introduction of the offset allows each latch, over time, to be exposed to the same pattern as the other latches. That is, the latches “see” different portions of the pattern at a given time, but over time, each can be exposed to the full pattern. Otherwise, each latch would “see” its own static pattern, different from the other latches, but the same over time with respect to itself. The offset can enhance diagnostic capabilities of the test pattern.

Abstract: In accordance with the present invention, a hard disk drive system is configured with logic that time correlates grown defects. The hard disk drive system time correlates grown defects by associating each occurrence of a grown defect with a time stamp. When the hard disk drive system receives a read defect data command sent by the host processor, the hard disk drive system returns time correlated grown defect information to the host processor. The host processor preferably executes a software program that processes the time correlated grown defect information to determine any changes in the number of grown defects that are occurring as a function of time.

Abstract: An integrated circuit device for use in a node of a communication system is provided. The integrated circuit device includes a memory configured to store data written thereto by a receiver associated with the node in accordance with a receiver clock, and to read data therefrom by a transmitter associated with the node in accordance with a transmitter clock. The integrated circuit device also includes a control logic circuit that is in communication with the memory, and is configured to send a control signal to the transmitter to adjust a speed of the transmitter clock responsive to an operating condition of the memory.

Abstract: In a communication system comprising first and second nodes, a multilevel amplitude modulated signaling technique is utilized. The first and second nodes may communicate over a Fibre Channel link or other medium. The first and second nodes comprise respective transmitter and receiver pairs, with the transmitter of the first node configured for communication with the receiver of the second node and the receiver of the first node configured for communication with the transmitter of the second node. The first node is configured to generate a signal for transmission over a serial data channel to the second node, the signal having a multilevel amplitude modulated format in which, within a given clock cycle of the signal, multiple bits are represented by a given signal level.

Abstract: In a communication system comprising first and second nodes, a transmit adaptive equalization technique is implemented utilizing ordered sets. The first and second nodes may communicate over a Fibre Channel link or other medium. The first and second nodes comprise respective transmitter and receiver pairs, with the transmitter of the first node configured for communication with the receiver of the second node and the receiver of the first node configured for communication with the transmitter of the second node. The first node is operative to receive from the second node information specifying an adjustment to one or more equalization parameters of the first node. The information is received in designated portions of one or more ordered sets transmitted from the second node to the first node in conjunction with initialization of a communication link between the first and second nodes. The first node adjusts the equalization parameter(s) in accordance with the received information.

Abstract: In a communication system comprising first and second nodes, a transmit adaptive equalization technique is implemented. The first and second nodes may communicate over a Fibre Channel link or other medium. The first and second nodes comprise respective transmitter and receiver pairs, with the transmitter of the first node configured for communication with the receiver of the second node and the receiver of the first node configured for communication with the transmitter of the second node. The first node receiver is operative to receive from the second node transmitter, responsive to a signal transmitted by the first node transmitter to the second node receiver, information specifying an adjustment to one or more equalization parameters of the first node transmitter. The first node adjusts the equalization parameter(s) in accordance with the received information.

Abstract: An optical switch of the multiple push button type for producing a plurality of control signals includes a housing and at least two sliders disposed within the housing. The sliders move between an initial position and at least two other positions. A pair of stationary light shields are disposed between said sliders in spaced apart relation, each of the shields having a plurality of apertures. Light emitting means are disposed between the stationary light shields. Separate light responsive means are disposed adjacent to each of the sliders. A pair of moveable light shields, each disposed between one of the stationary light shields and one of the light responsive means, each has a plurality of apertures and each is movable in response to movement of a separate one of the sliders. Circuitry responds to output of the light responsive means to produce the foregoing control signals, such output being dependent upon the position of the sliders.