Abstract: An avionics system in an aircraft for providing flight data from an onboard flight management computer (FMC) to requesting applications is disclosed. The system includes a flight management system (FMS) service layer executing on the FMC on a thread separate from a thread that executes FMS core functions. The FMS service layer provides a FMC networked node server for responding to queries from a plurality of external applications for data generated from the FMS core functions without interrupting the FMS core functions. The FMC networked node server is configured to: receive a request from a client application using a server specified API for data elements from a specified input flight plan; retrieve the specified input flight plan from the FMS core functions; extract the requested data elements; and output the requested data elements to the client application without affecting the active thread that executes FMS core functions.

Abstract: A system includes an aircraft avionics system and a portable computing device. The aircraft avionics system is configured to run one or more embedded avionics applications. The portable computing device is in operable communication with the aircraft avionics system and is configured to run one or more portable device applications. Each portable device application has resident therein a software development kit having libraries and utilities that enables the portable device application to: establish a secure connection with the aircraft avionics system, establish and maintain a required protocol with the embedded avionics application, and communicate with the embedded avionics application as specified by an application programming interface definition.

Abstract: A method in an aircraft for the validation of variable data is provided. The method comprises: receiving a request from an application program to retrieve data attributes for at least one data item to be entered via a GUI provided by the application program; requesting, from the flight management engine using an API, the data attributes for the at least one data item, wherein the data attributes identify at least one limit for data entry for the at least one data item including a minimum and/or maximum value for the at least one data item; receiving the requested data attributes from the flight management engine; and transmitting the data attributes to the application program; wherein the application program restricts data entry for the at least one data item in conformance with each limit provided by the data attributes for the at least one data item.

Abstract: An avionics system in an aircraft for providing flight data from an onboard flight management computer (FMC) to requesting applications is disclosed. The system includes a flight management system (FMS) service layer executing on the FMC on a thread separate from a thread that executes FMS core functions. The FMS service layer provides a FMC networked node server for responding to queries from a plurality of external applications for data generated from the FMS core functions without interrupting the FMS core functions. The FMC networked node server is configured to: receive a request from a client application using a server specified API for data elements from a specified input flight plan; retrieve the specified input flight plan from the FMS core functions; extract the requested data elements; and output the requested data elements to the client application without affecting the active thread that executes FMS core functions.

Abstract: A method in an aircraft for the validation of variable data is provided. The method comprises: receiving a request from an application program to retrieve data attributes for at least one data item to be entered via a GUI provided by the application program; requesting, from the flight management engine using an API, the data attributes for the at least one data item, wherein the data attributes identify at least one limit for data entry for the at least one data item including a minimum and/or maximum value for the at least one data item; receiving the requested data attributes from the flight management engine; and transmitting the data attributes to the application program; wherein the application program restricts data entry for the at least one data item in conformance with each limit provided by the data attributes for the at least one data item.

Abstract: A system includes an aircraft avionics system and a portable computing device. The aircraft avionics system is configured to run one or more embedded avionics applications. The portable computing device is in operable communication with the aircraft avionics system and is configured to run one or more portable device applications. Each portable device application has resident therein a software development kit having libraries and utilities that enables the portable device application to: establish a secure connection with the aircraft avionics system, establish and maintain a required protocol with the embedded avionics application, and communicate with the embedded avionics application as specified by an application programming interface definition.

Abstract: Methods for providing a flight management service in a cloud computing environment, the method includes: receiving, an object request by a server from a mobile device wherein the server is located in the cloud computing environment including: at least a flight management system (FMS) connected to a stateless object; processing, by the connected FMS hosted by the server, the object request generating a resource object for a particular flight plan wherein the resource object includes a data set; storing, by the connected FMS, the data set at the stateless object in the cloud environment; and sending, by the server, an object response from the connected FMS to the mobile device, for accessing the data set of the stateless object for the particular flight plan.

Abstract: Systems and methods are disclosed for dynamically detecting moving object trajectory conflict using estimated times of arrival. A method for dynamically detecting aircraft trajectory conflicts against a moving object may include: receiving, by one or more processors, one or more environmental inputs, the one or more environmental inputs including one or more object characteristic parameters of the moving object; determining, by the one or more processors, object movement data indicative of one or more projected movements of the moving object, based on the one or more environmental inputs; receiving, by the one or more processors, a flight trajectory of an aircraft; and dynamically determining, by the one or more processors, an aircraft estimated time of arrival at an intersection between the flight trajectory and the one or more projected movements of the moving object.

Abstract: Systems and methods are disclosed for brokering data exchanges between on-board and off-board systems of a vehicle. One method comprises receiving, at a data broker engine, one or more data requests from an origination system, wherein each of the one or more data requests specifies at least one or more of a request type and a target system. Then the data broker engine determines whether the request type is a one-time transmission, a periodic transmission, an event-triggered transmission, or a change-triggered transmission. Following the determination, the data broker engine retrieves data from the target system based on the determined request type and transmits the data to the origination system.

Abstract: Systems and methods are disclosed for brokering data exchanges between on-board and off-board systems of a vehicle. One method comprises receiving, at a data broker engine, one or more data requests from an origination system, wherein each of the one or more data requests specifies at least one or more of a request type and a target system. Then the data broker engine determines whether the request type is a one-time transmission, a periodic transmission, an event-triggered transmission, or a change-triggered transmission. Following the determination, the data broker engine retrieves data from the target system based on the determined request type and transmits the data to the origination system.

Abstract: Methods for providing a flight management service in a cloud computing environment, the method includes: receiving, an object request by a server from a mobile device wherein the server is located in the cloud computing environment including: at least a flight management system (FMS) connected to a stateless object; processing, by the connected FMS hosted by the server, the object request generating a resource object for a particular flight plan wherein the resource object includes a data set; storing, by the connected FMS, the data set at the stateless object in the cloud environment; and sending, by the server, an object response from the connected FMS to the mobile device, for accessing the data set of the stateless object for the particular flight plan.

Abstract: The present invention relates to a compound of formula (I) or (II), processes for preparing them, peptides including them and kits involving them.

Abstract: A rotary heat pump 10 comprises a vapor generator 20, a condenser 24/34, an evaporator 42 and an absorber 40 interconnected to provide cyclic fluid flow paths for a volatile fluid component and an absorbent fluid therefor. To allow operation of the pump close to the crystallisation boundary the pump includes crystallisation control means which cause the temperature of the fluid in the region prone to crystallisation to be raised when the onset of crystallisation is detected. For example the pressure increase upstream of a crystallisation site may cause warm fluid to be diverted directly or indirectly to increase the fluid temperature at the crystallisation site.

Abstract: A rotary heat pump 10 comprises a vapor generator 20, a condenser 24/34, an evaporator 42 and an absorber 40 interconnected to provide cyclic fluid flow paths for a volatile fluid component and an absorbent fluid therefor. To allow operation of the pump close to the crystallization boundary the pump includes crystallization control means which cause the temperature of the fluid in the region prone to crystallization to be raised when the onset of crystallization is detected. For example the pressure increase upstream of a crystallization site may cause warm fluid to be diverted directly or indirectly to increase the fluid temperature at the crystallization site.

Abstract: A coupling for high pressure liquid chromatographic columns of any length, individually, or by union of two columns together, in which an end fitting carries a secondary seal together with internal means for retaining the seal in place. The end fitting is designed as a unitary assembly wherein the secondary seal is secured into the end fitting as a unitary assembly of parts without the use of screw threaded members. A special screw and nut configuration of end fittings permits the same design to be used for columns of extremely short lengths.

Abstract: A replaceable cartridge column for use in high pressure liquid chromatograph pumping systems including a solid tube having a small bore therethrough carrying a packing material. The tube and terminated by a recess at each end which extends from the rim at the end of the tube inwardly and in communication with the bore. A plastic seal plug is disposed in the recess at each end to extend slightly beyond excess the length of the tube when so disposed and carries at its outer end a coaxial frit filter. The recess is provided with a flat bottom and the plastic plug has a corresponding bottom constructed to be positioned in face-to-face sealing opposition to fluid leakage and having further a flat sealing surface at its other end to engage a sealing surface of an end fitting of the liquid chromatographic pumping system and to provide a first, primary seal therewith independent of the rim of the column tube.

Abstract: Pump module for liquid chromatography for delivering the mobile phase to a separation column under high pressure including a cylinder containing a plunger and forming a syringe pump, a seal disposed between the plunger and cylinder, two positive action valves connect to the output of the pump either to a reservoir of said mobile phase or to a sample injection valve. The pump is dimensioned to accommodate most chromatographic analysis i.e. from about 10 ml to 40 ml.

Abstract: A coupler or union for passing fluid under pressure from a column or tube in which the tube is received within a chamber in fluid communication through the floor within said coupler and forming a zero dead volume seal therewith, an annular recess in the coupler or union surrounding the tube or column and containing a balanced hydraulic seal in contact with the recess wall and tube or column and opening in communication toward said dead volume seal so that leakage from the latter under high pressure fills and activates the balanced hydraulic seal to the line pressure. The coupler or union is particularly applicable for high pressure liquid chromatograph column connections.

Abstract: Plastic seal plugs insert into each end of an elution column tube and are provided with flat gasket portions extending laterally to cover each tube end, a spring loaded hand-tightenable nut drives an end fitting from each end of a column holder extending alomst the length of the column to put the gasket portions and the tube in compression and create a seal between the end fitting, tube, at interposed gasket, the latter being entirely contained against cold flow or deformation by a close fitting recess in the end fitting which entirely captures the plastic gasket and tube end.