Abstract: Embodiments provide for insertion devices for flexible analyte sensors that enable a user to select from a wide variety of different angles of sensor insertion. In an example, an insertion device comprises a guidance structure for supporting the flexible analyte sensor during insertion into skin, and an insertion angle adjustment component configured to manipulate the guidance structure that in turn adjusts the angle of flexible analyte sensor delivery to skin. In this way, insertion angle may readily be changed by a user or technician, depending on the application.

Abstract: Techniques regarding microfluidic chips with one or more vias filled with sacrificial plugs and/or manufacturing methods thereof are provided herein. For example, one or more embodiments described herein can comprise an apparatus, which can comprise a silicon device layer of a microfluidic chip comprising a plurality of vias extending through the silicon device layer. The plurality of vias comprise greater than or equal to about 100 vias per square centimeter of a surface of the silicon device layer and less than or equal to about 100,000 vias per square centimeter of the surface of the silicon device layer. Additionally, the apparatus can comprise a plurality of sacrificial plugs positioned in the plurality of vias.

Abstract: Embodiments provide a sensor insertion tool (SIT) that provides a motive force for insertion of an analyte sensor into/through skin. A SIT may be releasably locked to one or more components of a sensor insertion system, such that components of the sensor insertion system remain securely coupled during sensor insertion. A SIT may include a release member that unlocks or uncouples the SIT and the other components after sensor insertion. In various embodiments, a SIT may be a component of a sensor insertion system configured for assembly by an end user, a health care professional, and/or a caretaker prior to sensor insertion, and may act in cooperation with other sensor insertion system components. Additional components and methods of assembly and use are also provided herein.

Abstract: A system can detect an event at a first grid connected to a second grid via a meter monitored by a utility provider that distributes electricity via the second grid. A controller of a first grid can receive data including amounts of electricity consumption monitored by a corresponding plurality of sub-meters on the first grid and state information for energy storage systems on the first grid. The system can determine, responsive to the event, to modify a set point for one of the energy storage systems based on the state information and the amounts of electricity consumption monitored by the sub-meters on the first grid. The data processing system can provide, based on the determination, one or more commands to the controller to modify the set point for at least one of the plurality of energy storage systems on the first grid.

Abstract: A method for producing a flexible tooling liner for casting a ceramic core is presented. The method includes the steps of producing a three-dimensional (3D) reference object representative of a ceramic core to be cast, disposing the reference object into a containment vessel configured to receive a liquid flexible tooling material, filling the containment vessel with the liquid tooling material so that the reference object is encapsulated by the liquid tooling material on the surface whose topography is intended to be imparted, allowing the liquid tooling material to cure, and separating the cured flexible tooling along a parting surface into opposing portions and removing the reference the reference object.

Abstract: A device and method for delivering a device such as a sensor or fluid transport structure or a fluid transport structure sensor combination into, for example, mammalian skin. Such a device allows a sensor to penetrate mammalian skin without the use of an introducer device such as a needle. A device in accordance with embodiments of the present disclosure includes a housing for attachment to mammalian skin including an exit port for receiving the distal end of a biosensor and an injection activation device including a mechanism for forcing the sensing device from a first position within the housing, through the exit port to a second position, with sufficiently high velocity to partially penetrate the mammalian skin.

Abstract: Apparatus and method for exposing a partially processed photopolymer printing plate to post-exposure radiation and finishing radiation, the printing plate defining a whole area having a first full lateral dimension and a second full lateral dimension perpendicular to the first lateral dimension. A plurality of light-emitting diodes (LEDs) are arranged in one or more arrays; a surface for receiving the printing plate in a location disposed to receive the post exposure radiation and the finishing radiation; and one of more controllers connected to the one or more arrays to activate the one or more arrays to cause the plurality of sets of LEDs to emit radiation toward the printing plate. The plurality of LEDs includes at least a first set of LEDs to emit the post exposure radiation in a UVA spectral range and a second set of LEDs to emit the finishing radiation in a UVC spectral range.

Abstract: A system can detect an event at a first grid connected to a second grid via a meter monitored by a utility provider that distributes electricity via the second grid. A controller of a first grid can receive data including amounts of electricity consumption monitored by a corresponding plurality of sub-meters on the first grid and state information for energy storage systems on the first grid. The system can determine, responsive to the event, to modify a set point for one of the energy storage systems based on the state information and the amounts of electricity consumption monitored by the sub-meters on the first grid. The data processing system can provide, based on the determination, one or more commands to the controller to modify the set point for at least one of the plurality of energy storage systems on the first grid.

Abstract: Systems and methods for making a flexo plate, and plates, machines, readers, and computer readable media for use therewith. In the system, a plurality of processing machines, each configured to perform one or more process steps in a workflow, includes a controller, a variable operating parameter controlled by the controller, and a reader configured to read machine-readable indicia on the flexo plate. The machine-readable indicia (e.g. bar code, RFID tag, text) is configured for persistent readability downstream of washing (and cutting) steps, without printing in the printing step. The indicia may embody information including at least a plate identifier and instructions corresponding to the at least one variable operating parameter for each of the processing machines or information corresponding to an address in computer storage where the information resides.

Abstract: A method for producing a flexible tooling liner for casting a ceramic core is presented. The method includes the steps of producing a three-dimensional (3D) reference object representative of a ceramic core to be cast, disposing the reference object into a containment vessel configured to receive a liquid flexible tooling material, filling the containment vessel with the liquid tooling material so that the reference object is encapsulated by the liquid tooling material on the surface whose topography is intended to be imparted, allowing the liquid tooling material to cure, and separating the cured flexible tooling along a parting surface into opposing portions and removing the reference the reference object.

Abstract: Techniques regarding microfluidic chips with one or more vias filled with sacrificial plugs and/or manufacturing methods thereof are provided herein. For example, one or more embodiments described herein can comprise an apparatus, which can comprise a silicon device layer of a microfluidic chip comprising a plurality of vias extending through the silicon device layer. The plurality of vias comprise greater than or equal to about 100 vias per square centimeter of a surface of the silicon device layer and less than or equal to about 100,000 vias per square centimeter of the surface of the silicon device layer. Additionally, the apparatus can comprise a plurality of sacrificial plugs positioned in the plurality of vias.

Abstract: A method of in vivo conditioning of an indwelling sensor to reduce run-in time, (stabilization time) comprising: a) applying a first potential to the sensor and measuring a first current at the first potential; b) applying a second potential to the sensor and measuring a second current at the second potential; c) determining a relationship of the first current measured to the second current measured; repeating a, b, and c until the relationship between the first current measured and the second current measured has stabilized, thereby reducing sensor run-in time.

Abstract: Techniques regarding microfluidic chips with one or more vias filled with sacrificial plugs and/or manufacturing methods thereof are provided herein. For example, one or more embodiments described herein can comprise an apparatus, which can comprise a silicon device layer of a microfluidic chip comprising a plurality of vias extending through the silicon device layer. The plurality of vias comprise greater than or equal to about 100 vias per square centimeter of a surface of the silicon device layer and less than or equal to about 100,000 vias per square centimeter of the surface of the silicon device layer. Additionally, the apparatus can comprise a plurality of sacrificial plugs positioned in the plurality of vias.

Abstract: A method of manufacturing for finishing ceramic core flash. Locating a first hole on a ceramic core by a laser sensor on a robot. Probing for a center of the first hole by a force-torque sensor on the robot. Scanning for an axial position of a second hole on the ceramic core. Scanning for a third hole on the ceramic core. Probing for a center of the third hole. Determining axial and radial scale factors based on the first hole location and the third hole location. Uploading the axial and radial scale factors to the robot Multiplying the X component position by the axial scale factor and the Z component position by the radial scale factor in an array format. Cutting a designated scaled location along the ceramic core to remove flash. Repeating process for additional scaled locations along the ceramic core.

Abstract: A method of manufacturing for finishing ceramic core flash. Locating a first hole on a ceramic core by a laser sensor on a robot. Probing for a center of the first hole by a force-torque sensor on the robot. Scanning for an axial position of a second hole on the ceramic core. Scanning for a third hole on the ceramic core. Probing for a center of the third hole. Determining axial and radial scale factors based on the first hole location and the third hole location. Uploading the axial and radial scale factors to the robot Multiplying the X component position by the axial scale factor and the Z component position by the radial scale factor in an array format. Cutting a designated scaled location along the ceramic core to remove flash. Repeating process for additional scaled locations along the ceramic core.

Abstract: Systems and methods for operating continuous analyte monitoring (CAM) device are provided. In one example, a method comprises converting a first analyte data stream into analyte values reflective of a biological concentration of the analyte, obtaining one or more additional data streams from one or more adjunctive sensors, inferring based on the first data stream and the one or more additional data streams that conversion of the first data stream into analyte values is predicted to be inaccurate, and taking mitigating action to avoid inaccurate analyte values from being reported to a user. In this way, corrective measures can be taken to improve overall CAM device operation, quality of data provided via a CAM device may be enhanced, and user health and safety profile associated with the continuous analyte monitoring device may be improved.

Abstract: Systems and methods for making a flexo plate, and plates, machines, readers, and computer readable media for use therewith. In the system, a plurality of processing machines, each configured to perform one or more process steps in a workflow, includes a controller, a variable operating parameter controlled by the controller, and a reader configured to read machine-readable indicia on the flexo plate. The machine-readable indicia (e.g. bar code, RFID tag, text) is configured for persistent readability downstream of washing (and cutting) steps, without printing in the printing step. The indicia may embody information including at least a plate identifier and instructions corresponding to the at least one variable operating parameter for each of the processing machines or information corresponding to an address in computer storage where the information resides.