Patents by Inventor Robert Bruce Knox
Robert Bruce Knox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7514083Abstract: The present invention provides nucleic acid sequences coding Cyn d I, or at least one fragment thereof or the functional equivalent of such nucleic acid sequences. The present invention also provides expression vectors comprising such nucleic acid sequences and host cells transformed therewith. The present invention further provides isolated Bermuda grass pollen protein allergen Cyn d I or fragments thereof. Isolated Bermuda grass pollen protein allergens or antigenic or allergenic fragments thereof are useful for diagnosing and treating sensitivity in an individual to Bermuda grass pollen allergens.Type: GrantFiled: May 15, 1995Date of Patent: April 7, 2009Assignee: University of MelbourneInventors: Mohan Bir Singh, Penelope Smith, Robert Bruce Knox
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Patent number: 6740748Abstract: The present invention relates generally to the use of genetic engineering to induce developmental regulation in anther tissue of plants, and more particularly to induce nuclear male sterility, and to genetic sequences useful for same. More particularly, the present invention relates to the identification of a genomic clone and promoter capable of tissue- and development-specific expression which provides a means of tissue and developmental regulation in plants and more specifically a means of producing nuclear male sterile plants. Even more particularly, the present invention provides a genomic clone having a nucleotide sequence as set forth in SEQ ID NO. 1 or homologous sequences thereof such as the nucleotide sequence as set forth in SEQ ID NO. 3.Type: GrantFiled: August 7, 1995Date of Patent: May 25, 2004Assignee: The Univeristy of MelbourneInventors: Robert Bruce Knox, Mohan Bir Singh, Huiling Xu
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Patent number: 6451324Abstract: The present invention provides a nucleic acid sequences coding for the ryegrass pollen allergens Lol pIa and Lol pIb, purified Lol pIa and Lol pIb protein and fragments thereof, methods of producing recombinant Lol pIa and Lol pIb or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: May 3, 1995Date of Patent: September 17, 2002Assignee: The University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough
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Patent number: 6441157Abstract: The present invention provides nucleic acid sequences coding Cyn dI, or at least one fragment thereof or the functional equivalent of such nucleic acid sequences. The present invention also provides expression vectors comprising such nucleic acid sequences and host cells transformed therewith. The present invention further provides isolated Bermuda grass pollen protein allergen Cyn dI or fragments thereof. Isolated Bermuda grass pollen protein allergens or antigenic or allergenic fragments thereof are useful for diagnosing and treating sensitivity in an individual to Bermuda grass pollen allergens.Type: GrantFiled: October 30, 1992Date of Patent: August 27, 2002Assignee: University of MelbourneInventors: Mohan Bir Singh, Penelope Smith, Robert Bruce Knox
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Patent number: 6277383Abstract: The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: March 24, 1995Date of Patent: August 21, 2001Assignee: University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough, Cenk Suphioglu, Eng Kok Ong
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Patent number: 6265566Abstract: The present invention provides a nucleic acid sequences coding for the ryegrass pollen allergens Lol pIa and Lol pIb, purified LoI pIa and Lol pIb protein and fragments thereof, methods of producing recombinant Lol pIa and Lol pIb or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: December 29, 1993Date of Patent: July 24, 2001Assignee: ImmuLogic Pharmaceuticals, Inc.Inventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough
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Patent number: 6239269Abstract: The present invention provides a nucleic acid sequences coding for the ryegrass pollen allergens Lol pIa and Lol pIb, purified Lol pIa and Lol pIb protein and fragments thereof, methods of producing recombinant Lol pIa and Lol pIb or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: May 3, 1995Date of Patent: May 29, 2001Assignee: The University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough
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Patent number: 6215045Abstract: The present invention relates generally to the use of genetic engineering to induce developmental regulation in anther tissue of plants, and more particularly to induce nuclear male sterility, and to genetic sequences useful for same. More particularly, the present invention relates to the identification of a genomic clone and promoter capable of tissue- and development-specific expression which provides a means of tissue and developmental regulation in plants and more specifically a means of producing nuclear male sterile plants. Even more particularly, the present invention provides a genomic clone having a nucleotide sequence as set forth in SEQ ID NO. 1 or homologous sequences thereof such as the nucleotide sequence as set forth in SEQ ID NO. 3.Type: GrantFiled: March 6, 1998Date of Patent: April 10, 2001Assignee: The University of MelbourneInventors: Robert Bruce Knox, Mohan Bir Singh, Huiling Xu
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Patent number: 6214358Abstract: The present invention provides nucleic acid sequences coding Cyn d I, or at least one fragment thereof or the functional equivalent of such nucleic acid sequences. The present invention also provides expression vectors comprising such nucleic acid sequences and host cells transformed therewith. The present invention further provides isolated Bermuda grass pollen protein allergen Cyn d I or fragments thereof. Isolated Bermuda grass pollen protein allergens or antigenic or allergenic fragments thereof are useful for diagnosing and treating sensitivity in an individual to Bermuda grass pollen allergens.Type: GrantFiled: May 15, 1995Date of Patent: April 10, 2001Assignee: ImmuLogic Pharamaceutical Corp.Inventors: Mohan Bir Singh, Penelope Smith, Robert Bruce Knox
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Patent number: 6197313Abstract: The present invention provides a nucleic acid sequences coding for the ryegrass pollen allergens Lol pIa and Lol pIb, purified Lol pIa and Lol pIb protein and fragments thereof, methods of producing recombinant Lol pIa and Lol pIb or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: May 3, 1995Date of Patent: March 6, 2001Assignee: University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough
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Patent number: 6180368Abstract: The present invention provides a nucleic acid sequences coding for the ryegrass pollen allergens Lol pIa and Lol pIb, purified Lol pIa and Lol pIb protein and fragments thereof, methods of producing recombinant Lol pIa and Lol pIb or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: March 31, 1995Date of Patent: January 30, 2001Assignee: University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough
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Patent number: 5965455Abstract: The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: May 2, 1995Date of Patent: October 12, 1999Assignee: University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough, Cenk Suphioglu, Eng Kok Ong
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Patent number: 5869333Abstract: The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: May 2, 1995Date of Patent: February 9, 1999Assignee: University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough, Cenk Suphioglu, Eng Kok Ong
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Patent number: 5840316Abstract: The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: February 14, 1994Date of Patent: November 24, 1998Assignee: University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough, Cenk Suphioglu, Eng Kok Ong
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Patent number: 5736362Abstract: The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: December 29, 1993Date of Patent: April 7, 1998Assignee: The University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Penelope Smith, Asil Avjioglu, Piyada Theerakulpisut, Terryn Hough, Cenk Suphioglu, Eng Kok Ong
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Patent number: 5736149Abstract: The present invention provides a nucleic acid having a nucleotide sequence coding for Sor h I, a major allergen of Sorghum halepense, and fragments thereof. The present invention also provides purified Sor h I or at least one fragment thereof, produced in a host cell transformed with a nucleic acid sequence coding for Sor h I, or at least one fragment thereof and fragments of Sor h prepared synthetically. Sor h I and fragments thereof are useful for diagnosing, treating, and preventing allergy to Johnson grass pollen.Type: GrantFiled: June 6, 1995Date of Patent: April 7, 1998Assignee: The University of MelbourneInventors: Asil Avjioglu, Mohan Bir Singh, Robert Bruce Knox
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Patent number: 5721119Abstract: The present invention provides nucleic acid sequences coding for two ryegrass pollen allergen Lol p Ib family members, purified Lol p Ib.1 and Lol p Ib.2 proteins and fragments thereof, methods of producing recombinant Lol p Ib.1 or Lol p Ib.2 or at least one fragment thereof or derivative or homologue thereof, and methods of using the nucleic acid sequences, proteins and peptides of the invention.Type: GrantFiled: May 2, 1995Date of Patent: February 24, 1998Assignee: University of MelbourneInventors: Mohan Bir Singh, Robert Bruce Knox, Eng Kok Ong
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Patent number: 5691167Abstract: The present invention provides a nucleic acid having a nucleotide sequence coding for Sor h I, a major allergen of Sorghum halepense, and fragments thereof. The present invention also provides purified Sor h I or at least one fragment thereof, produced in a host cell transformed with a nucleic acid sequence coding for Sor h I, or at least one fragment thereof and fragments of Sor h prepared synthetically. Sor h I and fragments thereof are useful for diagnosing, treating, and preventing allergy to Johnson grass pollen.Type: GrantFiled: December 29, 1993Date of Patent: November 25, 1997Assignees: The University of Melbourne, ImmuLogic Pharmaceutical CorporationInventors: Asil Avjioglu, Mohan Bir Singh, Robert Bruce Knox