Abstract: Compounds of Formula (I) are provided herein. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions, including conditions characterized by excessive cellular proliferation, such as cancer and tumors, as well as viral infections such as HIV.

Abstract: This invention embodies golf clubs and heads providing visual, auditory, and/or tactile aids useful to a golfer in determining whether a golf ball has been accurately struck. The head of the golf club is designed to produce a fundamental musical tone upon impact with a golf ball at the sweet spot of the club face. When a golf ball is struck at areas outside of the sweet spot, the head produces audible harmonic overtones that resonate above the fundamental pitch. Furthermore, the shaft of the golf club is preferably made from a resonant material that is attached to the head at a vibratory node of the head such that when a golf ball has been accurately struck using the sweet spot of the club face, no harmonic vibrations are transferred along the shaft to the grip.

Abstract: This invention is for a percussion instrument that when struck produces a sustained tone. The instrument is shaped to produce a harmonious tone by tuning the appropriate overtones. The fundamental tone generated by the instruments disclosed herein are controllably tunable to within fractions of a hertz (Hz). Also disclosed are instruments that minimize and dampen unwanted overtones to generate a substantially pure tone. Also provided are related methods for generating a sustained tone as well as methods and devices for generating a beat, wherein a pair of the percussion instruments of the present invention having different tone frequencies provide the beat.

Abstract: A sharping lever for shortening the length of a vibrating string on a folk harp is described. The sharping lever is mounted along the neck of the harp directly below the tuning pin which secures one end of the vibrating string. The lever includes an L-shaped mounting bracket which is attached securely to the side of the neck of the harp. The sharping lever also includes a rotatably mounted cam which contacts the string along a tip portion. The rotational movement presses the string against a fixedly mounted fret. The fret is located at a position on the mounting bracket so as to precisely define the shortened length of the vibrating string thereby raising its frequency by one-half tone.