Patents by Inventor Robert Busby

Robert Busby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IBOGAINE COMBINATION TREATMENT
    Publication number: 20230100844
    Abstract: The present disclosure is directed to methods of improving the therapeutic effectiveness and safety profile of ibogaine for the treatment of conditions including, but not limited to, alcoholism, substance abuse disorder, and opioid use disorder.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 30, 2023
    Inventors: Srinivas G. RAO, Glenn SHORT, Carrie BOWEN, Robert BUSBY
  • Compositions and Methods for Reducing the Toxicity of Certain Toxins
    Publication number: 20100310541
    Abstract: Compositions and methods for reducing the toxic effect of certain peptide toxins by administering an agent that directly or indirectly reduces disulfide bonds that are important for maintaining the toxin in an active conformation. Also described are compositions and methods for reducing the toxic effect of toxins that contain a heavy metal using an agent that destabilizes the binding of a metal ion that is important for toxin activity.
    Type: Application
    Filed: May 27, 2008
    Publication date: December 9, 2010
    Applicant: IRONWOOD PHARMACEUTICALS, INC.
    Inventors: Marco Kessler, Mark G. Currie, Robert Busby
  • Methods for improving secondary metabolite production in fungi
    Publication number: 20090075327
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Application
    Filed: March 7, 2001
    Publication date: March 19, 2009
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers
  • Methods for improving secondary metabolite production of fungi
    Publication number: 20060263864
    Abstract: Methods for improving secondary metabolite production by modulating certain genes involved in secondary metabolite production, including genes encoding CreA, AreA, GanB, Gna3, FadA, Gna1, Gpa1, RfeH, An09, PacC, Lys14, LovU, Ste7, Pde2, Nc1, Vps34 and fungal homologs thereof.
    Type: Application
    Filed: December 3, 2002
    Publication date: November 23, 2006
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Douglas Holtzman, Kevin Madden, Mary Maxon, G. Milne, Thea Norman, John Royer, Jeff Silva, Eric Summers, Lixin Zhang, Maria Mayorga, Toby Feibelman, Reed Doten
  • Methods for improving secondary metabolite production in fungi
    Patent number: 6949356
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: September 27, 2005
    Assignee: Microbia, Inc.
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers
  • Inhibitors of fungal invasion
    Publication number: 20040106663
    Abstract: This invention relates to isoxazole-based inhibitors of fungal invasion.
    Type: Application
    Filed: September 8, 2003
    Publication date: June 3, 2004
    Inventors: John Jeffrey Talley, Angelika Fretzen, Craig Zimmerman, Timothy Barden, Jing Jing Yang, Eduardo Martinez, Robert Busby, Etchell A. Cordero, Fariba Houman Cipriano, Christine M. Pierce, Eric F. Summers
  • Methods for improving secondary metabolite production in fungi
    Publication number: 20020128250
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Application
    Filed: March 7, 2001
    Publication date: September 12, 2002
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers