Abstract: The invention is directed towards an Aerodynamic Automated Biological Assay Device (“AABAD”) comprising an aerodynamic substrate having a microfluidic cassette and an electronic module, and a system and a method of deploying the same to detect biological agents and hazards suspended in an atmosphere. The AABAD may be in the form/shape of a maple seed/fruit to induce autorotation. A plurality of AABADs are dispersed into the atmosphere from an aircraft or drone. The AABADs rotate via centrifugal forces without motor or active propulsion system while descending to the ground, wherein during the descent, the AABADs microfluidic cassettes collect and process the air samples via a centrifugal force formed from the autorotation generated by the airborne carrier, and to analyze and transmits the results to a remote location.