Abstract: A method of preparing an implantable biomaterial film includes inputting a combination of a polymer and a neuro-regenerative agent or an immunosuppressive agent into an extruder. The method includes melting the polymer within the extruder. The method also includes extruding the combined polymer and the neuro-regenerative agent or the immunosuppressive agent to form the implantable biomaterial film.

Abstract: The present disclosure provides tissue wrap devices with embedded three dimensional attachment features, methods of manufacturing three-dimensional attachment features for tissue wrap devices, and methods of using a nerve wrap device to protect a damaged nerve. Tissue wrap devices of the present disclosure may include a sheet of biocompatible material, the sheet having a first side, a second side, a middle portion, a first outer portion, and a second outer portion, the first side of the first outer portion being configured to overlap and interface with the second side of the second outer portion when the sheet is transitioned to a rolled configuration; wherein the first side of the first outer portion comprises a plurality of three dimensional attachment features; and wherein the plurality of three dimensional attachment features are configured to engage with the second side of the second outer portion to maintain the sheet in the rolled configuration.

Abstract: An electrode apparatus may include a handle, a cannula extending from a distal end of the handle and having at least one lumen, a ground wire extending through the cannula, and an electrode wire extending through the handle and the cannula, the electrode wire being extendable and retractable relative to a distal end of the cannula. The apparatus may also include a hook, provided in the cannula, and being extendable and retractable relative to the cannula.

Abstract: A method of preparing an implantable biomaterial includes combining a polymer comprising polydioxanone with a neuro-regenerative agent or an immunosuppressive agent comprising at least one immunophilin ligand, and melting the polymer. The method further includes extruding the combined polymer and the neuro-regenerative agent or immunosuppressive agent to form the implantable biomaterial.

Abstract: A method of preparing an implantable biomaterial includes combining a polymer with a neuro-regenerative agent or immunosuppressive agent selected from a group comprising at least one of: rapamycin, cyclosporine A, or analogs thereof, melting the polymer, and extruding the polymer and the neuro-regenerative agent or immunosuppressive agent to form the implantable biomaterial.

Abstract: A feminine care absorbent article includes an outer cover and an absorbent structure in superposed relation to the outer cover and defining a bodyfacing surface. A lotion formulation is deposited on the bodyfacing surface in discrete locations targeted for specific regions of the wearer's body.

Abstract: A feminine care absorbent article includes an outer cover and an absorbent structure in superposed relation to the outer cover and defining a bodyfacing surface. A lotion formulation is deposited on the bodyfacing surface in discrete locations targeted for specific regions of the wearer's body.

Abstract: Opioid-containing pharmaceutical compositions are provided which are useful in effecting transdermal delivery of a therapeutic dose of the opioid to the systemic circulation of a mammal. These pharmaceutical compositions consist essentially of the opioid, a penetration enhancer which is at least one of a saturated fatty alcohol or fatty acid of 8-15 carbon atoms or of an unsaturated fatty alcohol or fatty acid of 8-18 carbon atoms, and a suitable pharmaceutical carrier, preferably propylene glycol.

Abstract: A laminate of a first layer of a lamellar heterogeneous blend of a polyolefin and a condensation polymer incompatible with the polyolefin, and a second layer of a polyolefin, said layers being melt bonded together.