Patents by Inventor Robert C Gensure

Robert C Gensure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion proteins of collagen-binding domain and parathyroid hormone
    Patent number: 8450273
    Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
    Type: Grant
    Filed: April 9, 2008
    Date of Patent: May 28, 2013
    Assignees: The Board of Trustees of the University of Arkansas, Ochsner Clinic Foundation, National University Corporation Kagawa University
    Inventors: Joshua Sakon, Robert C. Gensure, Osamu Matsushita
  • FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE
    Publication number: 20100129341
    Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
    Type: Application
    Filed: April 9, 2008
    Publication date: May 27, 2010
    Inventors: Joshua Sakon, Robert C. Gensure, Osamu Matsushita
  • Tip39 polypeptides
    Publication number: 20040176285
    Abstract: The invention relates to truncated TIP39 polypeptides and chimeric PTHrP/TIP polypeptides. The polypeptides are used as agonists or antagonists of PTH receptors in various medical conditions.
    Type: Application
    Filed: February 17, 2004
    Publication date: September 9, 2004
    Inventors: Harald Juppner, Thomas J Gardella, Kenneth P Jonsson, Markus R John, Robert C Gensure