Abstract: The present disclosure relates to methods and kits for analysis of polypeptides. In some embodiments, the present methods and kits employ barcoding and nucleic acid encoding of molecular recognition events, and/or detectable labels.

Abstract: Kits and methods of using the kits for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample analysis kits employ nucleic acid encoding and/or nucleic acid recording of a molecular interaction and/or reaction, such as recognition events (e.g., between an antigen and an antibody, between a modified terminal amino acid residue, or between a small molecule or peptide therapeutic and a target, etc.). Additional barcoding reagents, such as those for cycle-specific barcoding (e.g., “clocking”), compartment barcoding, combinatorial barcoding, spatial barcoding, or any combination thereof, may be included in the kits. The sample may comprise macromolecules, including peptides, polypeptides, and proteins, and the recording may generate molecular interaction and/or reaction information, and/or polypeptide sequence information.

Abstract: A package is capable of enclosing a food product in two different gaseous atmospheres at different times. Initially, the food product may be packaged in a low oxygen atmosphere in order to prolong the shelf life of the product. When it is time to sell the product for example, it may be desirable to supply oxygen to the food product. In the case of red meats, the oxygenation process causes the meat to turn a bright red color. The package includes a tray covered by a film with a plurality of apertures formed in the tray. The package may be maintained at a pressure below atmospheric pressure. The apertures are covered by a bacterial barrier layer covered by resealable tape which can be removed to allow air ingress and then resealed to protect the integrity of the tray contents.

Abstract: A package is capable of enclosing a food product in two different gaseous atmospheres at different times. Initially the food product may be packaged in a low oxygen atmosphere in order to prolong the shelf life of the product. When it is time to sell the product for example, it may be desirable to supply oxygen to the food product. In the case of red meats, the oxygenation process causes the meat to turn a bright red color. The package includes a tray covered by a film with a plurality of apertures formed in the tray. The apertures are covered by a resealable gas impermiable tape which can be removed to allow air ingress and then resealed to protect the integrity of the tray contents.

Abstract: A system for monitoring carbon monoxide (CO) levels produced by the operation of a vehicle's engine. The system includes a detector in the vehicle's passenger compartment for detecting the concentration of CO inside the compartment and circuitry for generating a HIGH CO signal when the detected concentration of CO inside the compartment is greater than a predetermined level. The system disables the operation of the engine in response to the HIGH CO signal. The system also senses a status condition of the vehicle and inhibits the disabling of the engine when the status condition is sensed.

Abstract: A flexible pouch package for fluid products including a composite bag having inner and outer package walls formed of flexible film folded over and sealed together about the outer edges thereof to define a chamber therein. The package may include an easy open feature.

Abstract: A case sealed by a strip of pressure-sensitive tape having an integral end portion of the tape at an end thereof folded back on the adhesive face of the tape and adhered thereto to form a tab which is unadhered to the case for being grasped and pulled to peel the tape away from the case, and a method of and apparatus for taping cases with this easy-open feature.

Abstract: A method of opening a folded web of flexible heat-sealable packaging material prior to formation of the material into sealed reclosable packages. The web has a pair of interlockable reclosable closure strips extending longitudinally of the web on an inside face of the web, and one section of the web is folded over on another section of the web so that the closure strips are interlocked. The method comprises advancing the folded web in a first plane to a web-opening station, and opening the folded web while maintaining the closure strips interlocked as the web advances through the web-opening station. The web is opened by diverting both sections of the web relative to one another so that they assume a co-planar position in a second plane different from the first plane.

Abstract: An escapement system in which units are movable by and with an endless conveyor in an endless path, and an escapement system is provided for retarding the units as they move through a part of their path, then releasing them; the system being incorporated in packaging apparatus in which the endless conveyor is a wheel and the units are sealing dies on the wheel.

Abstract: Method of and apparatus for forming filling and sealing packages in which flexible packaging material is formed into tubing, the tubing is fed downwardly and transversely heat sealed at package length intervals by closing a pair of sealing members, the seal area is cut to form a top seal of the package being completed and a bottom seal for the next package to be formed, a quantity of product with which the packages are to be filled is delivered into the lower end of the tubing to provide a fill for each package, the tubing is pinched closed, after the delivery of each fill, above and below the level of the next seal to be made, the pinches are maintained as the sealing members are opened, following the formation of the aforementioned top and bottom seals, to keep product for the next fill from dropping down on the bottom seal, and to hold the package being completed from dropping away, and air is blown on the top and bottom seals to cool them while the pinches are maintained.

Abstract: A carton loading machine comprising an endless conveyor carrying a series of holders each adapted to hold an erected carton in upright position and movable to move each holder from a carton receiving station for entry of an erected carton in the holder from the outside of the conveyor to a loading station for loading the carton and thence to a discharage station for discharge of the loaded carton, each holder having a fixed side and a movable side and latch members associated with said sides, the latch member associated with the fixed side and the movable side and latch member associated therewith being movable between open and closed positions.

Abstract: Method of and apparatus for forming, filling and sealing packages wherein a web of flexible packaging interval is formed into tubing around a mandrel and intermittently fed downwardly in package length increments by intermittently moving portions of continuously driven belts into engagement with the tubing for a predetermined interval.

Abstract: A case sealed by a strip of pressure-sensitive tape having an integral end portion of the tape at an end thereof folded back on the adhesive face of the tape and adhered thereto to form a tab which is unadhered to the case for being grasped and pulled to peel the tape away from the case, and a method of and apparatus for taping cases with this easy-open feature.

Abstract: A package comprising a wrapper formed from a single web of flexible sheet material formed into a tube having overlapping edge margins sealed together to form a single longitudinal seam for the tube lying substantially in the plane of one wall of the package, and a pair of end seals at opposite ends of the package, at least one end seal comprising end portions of two opposite walls of the tube sealed together in face-to-face relation in a plane extending longitudinally of the tube and generally at right angles to the plane of the overlapping edge margins forming the longitudinal seam.

Abstract: A pack or bundle comprising a bag of thermoplastic film such as polyethylene, individual packages of rolls of paper, such as packages of four rolls of toilet tissue, packed in the bag, a closure panel inserted in the bag engaging the contents, the panel being heat-sealable on its outside face, the bag having a marginal lip at its mouth projecting beyond the closure panel folded over on the outside face of the closure panel and heat-sealed thereto to close the bag, and the method of making such bundles involving inserting the contents and the closure into the bag through its mouth, and folding over the lip and heat-sealing it to the panel.

Abstract: A method of and apparatus for wrapping units to be wrapped, such as two rolls of paper, in which transverse lines of weakness are formed in a web of flexible sheet wrapping material at measured intervals along the length of the web corresponding to wrapper length as the web is continuously fed forward, the web is formed into a tube around the units with the lines of weakness extending girthwise of the tube and spaced lengthwise of the tube at the wrapper length intervals, the units are fed into the tube one after another spaced lengthwise in the tube at wrapper length intervals and located between the lines of weakness, the tube with the units therein is continuously fed forward at a predetermined speed, and the leading wrapper of the tube with a unit therein is pulled forward at higher speed to sever it from the tube at the line of weakness between it and the preceding wrapper.

Abstract: A form-fill-seal packaging method and apparatus in which a web of flexible packaging material is pulled from a supply and fed over a device for forming it into tubing, product to be packaged is provided in the tubing, and the tubing is sealed to form packages, and in which the web is pulled forward from the supply as one operation and the tubing is drawn forward and thereby taken up as an accompanying but separate operation with the take-up such that the web is pulled over the forming device under tension.

Abstract: Method of and apparatus for wrapping reams of paper or the like in which the ream being wrapped is placed on an elevator mechanism at a lower level and raised by the elevator mechanism to an upper level. The elevator mechanism comprises a central support and two outboard supports extending endwise of the ream. The outboard supports are movable inwardly from an outer position wherein they are spaced outwardly from the central support. The outboard supports occupy their outer position as the ream is placed on the supports and while the ream is being raised. As the ream is raised, it engages a wrapper sheet and portions of the wrapper sheet fold down on the sides of the ream. When the ream is raised, underfolders move in under the ream from opposite sides of the ream to fold portions of the sheet in under the bottom of the ream.

Abstract: Method of and apparatus for squaring reams of paper as they are fed toward a wrapper, the squaring up being accomplished as the reams are moving forward toward the wrapper.

Abstract: Apparatus for feeding stacks of sheets, in particular reams of paper, comprising a table along which the stacks are pushed forward by the flights of a flight conveyor, each flight having a foot adapted to support the stack, and the apparatus having means for lifting each stack, after it has been placed on the table in position for being pushed forward by a flight, to enable the foot of the flight to come under the stack.