Abstract: A method for the treatment of a patient suffering from an endogenous behavioral disorder in order to ameliorate at least some behavioral aspects of the disorder, the method comprising administering to the patient a therapeutic quantity of at least one ACE inhibitor. Behavioral aspects of endogenous disorders such as attention deficit disorder (ADD), obsessive-compulsive disorder (OCD), oppositional explosive defiant disorder (OEDD), anxiety and panic disorders (APD) and temper, rage and outburst behavior disorder (TROBD), are ameliorated by a regimen of ACE inhibitor.

Abstract: Receptor blocker (antagonist) drugs which suppress the binding of the D4 class of leukotriene molecules to leukotriene receptors can reduce the frequency and severity of recurrent primary headaches, including migraine and cluster headaches. Various LTD4 receptor blockers are commercially available, including montelukast and zafirlukast. In the past, these drugs have been used to treat asthma. During human clinical trials on asthma patients, headaches were one of the most commonly reported side effects of those two drugs; therefore, they apparently were never tested as agents which might prevent or reduce migraine or cluster headaches. However, it has been shown that in at least some patients who suffer from acute recurrent migraines, LTD4 receptor blockers can greatly reduce the frequency, duration, and/or severity of their headaches, when taken chronically on a daily basis.

Abstract: A method for the treatment of a patient suffering from a behavioral disorder, comprising administering to the patient a therapeutic quantity of at least one ACE inhibitor. Disorders such as attention deficit disorder (ADD), obsessive-compulsive disorder (OCD), oppositional explosive defiant disorder (OEDD), anxiety and panic disorders (APD) and temper, rage and outburst behavior disorder (TROBD) are ameliorated by a regimen of ACE inhibitor.

Abstract: A method is disclosed for using leukotriene (LT) antagonist drugs to prevent and treat recurrent primary headaches, which includes migraine headaches and cluster headaches. LT antagonist drugs (such as montelukast and zafirlukast) are commercially available, and they are safe for long-term chronic use without problems of tolerance or dependence. These drugs, taken daily in pill form, are conventionally used for treating asthma. In a clinical trial, LT antagonists taken orally each day reduced the frequency, duration, and severity of migraines, and reduced sensitivity to perfume as a triggering factor. LT antagonists were also found to increase the effectiveness of “triptan” drugs (such as sumatriptan) when used to treat acute migraine headaches.