Patents by Inventor Robert C. Liddington

Robert C. Liddington has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210221873
    Abstract: Disclosed are antibodies that bind to the stem region of influenza hemagglutinin in the neutral pH conformation, hemagglutinin epitopes in the stem region, and methods of making and using both.
    Type: Application
    Filed: September 14, 2020
    Publication date: July 22, 2021
    Inventors: Wayne A. Marasco, Jianhua Sui, Robert C. Liddington
  • Patent number: 10774134
    Abstract: Disclosed are antibodies that bind to the stem region of influenza hemagglutinin in the neutral pH conformation, hemagglutinin epitopes to the stem region, and methods of making and using both.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: September 15, 2020
    Assignees: Dana-Farber Cancer Institute, Inc., Burnham Institute for Medical Research
    Inventors: Wayne A. Marasco, Jianhua Sui, Robert C. Liddington
  • Publication number: 20190062408
    Abstract: Disclosed are antibodies that bind to the stem region of influenza hemagglutinin in the neutral pH conformation, hemagglutinin epitopes to the stem region, and methods of making and using both.
    Type: Application
    Filed: June 20, 2018
    Publication date: February 28, 2019
    Inventors: Wayne A. MARASCO, Jianhua Sui, Robert C. Liddington
  • Publication number: 20180312575
    Abstract: The invention provides human scFv antibodies and monoclonal antibodies that neutralize influenza virus. Also provided are methods of treating and/or preventing a influenza related disease or disorder such bird flu The invention also provides methods of vaccinating a patient against influenza. Also provided are methods of diagnosing influenza-related diseases or disorders and methods of detecting the presence of a influenza in a sample.
    Type: Application
    Filed: March 20, 2018
    Publication date: November 1, 2018
    Inventors: Wayne A. Marasco, Jianhua Sui, Robert C. Liddington
  • Patent number: 9951122
    Abstract: The invention provides human scFv antibodies and monoclonal antibodies that neutralize influenza virus. Also provided are methods of treating and/or preventing a influenza related disease or disorder such bird flu The invention also provides methods of vaccinating a patient against influenza. Also provided are methods of diagnosing influenza-related diseases or disorders and methods of detecting the presence of a influenza in a sample.
    Type: Grant
    Filed: August 12, 2013
    Date of Patent: April 24, 2018
    Assignees: DANA-FARBER CANCER INSTITUTE, INC., BURNHAM INSTITUTE FOR MEDICAL RESEARCH
    Inventors: Wayne A. Marasco, Jianhua Sui, Robert C. Liddington
  • Publication number: 20140011982
    Abstract: The invention provides human scFv antibodies and monoclonal antibodies that neutralize influenza virus. Also provided are methods of treating and/or preventing a influenza related disease or disorder such bird flu The invention also provides methods of vaccinating a patient against influenza. Also provided are methods of diagnosing influenza-related diseases or disorders and methods of detecting the presence of a influenza in a sample.
    Type: Application
    Filed: August 12, 2013
    Publication date: January 9, 2014
    Applicants: BURNHAM INSTITUTE FOR MEDICAL RESEARCH, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Wayne A. Marasco, Jianhua Sui, Robert C. Liddington
  • Publication number: 20120128684
    Abstract: Disclosed are antibodies that bind to the stem region of influenza hemagglutinin in the neutral pH conformation, hemagglutinin epitopes in the stem region, and methods of making and using both.
    Type: Application
    Filed: August 25, 2009
    Publication date: May 24, 2012
    Applicants: Burnham Institute for Medical Research, Dana-Farber Cancer Institute, Inc.
    Inventors: Wayne Marasco, Jianhua Sui, Robert C. Liddington
  • Publication number: 20110038935
    Abstract: The invention provides human scFv antibodies and monoclonal antibodies that neutralize influenza virus. Also provided are methods of treating and/or preventing a influenza related disease or disorder such bird flu The invention also provides methods of vaccinating a patient against influenza. Also provided are methods of diagnosing influenza-related diseases or disorders and methods of detecting the presence of a influenza in a sample.
    Type: Application
    Filed: December 8, 2008
    Publication date: February 17, 2011
    Inventors: Wayne A. Marasco, Jianhua Sui, Robert C. Liddington
  • Patent number: 6384188
    Abstract: Substance which bind with high affinity to endotoxin (lipopolysaccharide [LPS]), and which are useful for the prevention or treatment of, for example, Gram-negative and Gram-positive bacterial sepsis, and for the treatment of bacterial and fungal infections as well as for neutralizing effects associated with heparin. The substances are LPS-binding peptides comprising an LPS-binding domain. DNA sequences encoding peptides, recombinant microorganisms containing the DNA, pharmaceutical compositions containing the peptides of the invention, and diagnostic kits. Methods for the detection and removal of bacterial LPS from solutions.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 7, 2002
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Adolf Hoess, Robert C. Liddington, George R. Siber