Abstract: A simulator is disclosed. A cockpit model comprising a plurality of cockpit model parts that collectively correspond to a simulated cockpit in a simulated vehicle is maintained. For each frame of a plurality of frames, a plurality of cockpit view frustums are determined, each cockpit view frustum corresponding to a different cockpit view of a plurality of cockpit views of the simulated cockpit. Shared cockpit scene information comprising a set of cockpit model parts that are within any of the plurality of cockpit views is generated based on the plurality of cockpit view frustums. A processing device submits to a graphics processing unit (GPU) the shared cockpit scene information and GPU instructions that direct the GPU to generate a plurality of cockpit view images that correspond to the plurality of cockpit views from the shared cockpit scene information. The GPU generates the plurality of cockpit view images.

Abstract: A simulator is disclosed. A cockpit model comprising a plurality of cockpit model parts that collectively correspond to a simulated cockpit in a simulated vehicle is maintained. For each frame of a plurality of frames, a plurality of cockpit view frustums are determined, each cockpit view frustum corresponding to a different cockpit view of a plurality of cockpit views of the simulated cockpit. Shared cockpit scene information comprising a set of cockpit model parts that are within any of the plurality of cockpit views is generated based on the plurality of cockpit view frustums. A processing device submits to a graphics processing unit (GPU) the shared cockpit scene information and GPU instructions that direct the GPU to generate a plurality of cockpit view images that correspond to the plurality of cockpit views from the shared cockpit scene information. The GPU generates the plurality of cockpit view images.

Abstract: Mechanisms for externally directing graphics processing unit data are disclosed. A simulator module includes an external application interface that is configured to communicate with an external application that is independent of the simulator module. The simulator module is configured to receive from the external application via the external application interface first user data and provide the first user data to a graphics processing unit (GPU) for use by a first shader function for image rendering during a first period of time. The simulator module continuously generates simulation data associated with a simulation and provides the simulation data to the GPU for the image rendering during the first period of time.

Abstract: Mechanisms for externally directing graphics processing unit data are disclosed. A simulator module includes an external application interface that is configured to communicate with an external application that is independent of the simulator module. The simulator module is configured to receive from the external application via the external application interface first user data and provide the first user data to a graphics processing unit (GPU) for use by a first shader function for image rendering during a first period of time. The simulator module continuously generates simulation data associated with a simulation and provides the simulation data to the GPU for the image rendering during the first period of time.

Abstract: The identification of the most sensitive sites of Clostridium histolyticum collagenase Class 1 to proteolysis by proteases present during the fermentation and purification of the enzyme is described. Culture supernatant obtained after fermentation of C. histolyticum is used as the starting material for further purification of the enzyme. Native collagenase Class 1 and its proteolytic fragments are partially purified by a combination of hydrophobic interaction and strong anion exchange chromatographies. The pools containing enriched levels of the proteolytic fragments are further purified by high performance anion exchange chromatography. These polypeptides are then characterized by Q-TOF mass spectroscopy. A total of three sensitive bonds are identified along with substitution and deletion strategies that will result in resistance of the enzyme to proteolytic degradation.

Abstract: The invention teaches a method for improving the ability to determine a polyvalent substance via use of an immunoaggregate during the assay. The immunoaggregate eliminates substances which can lead to incorrect results otherwise.