Patents by Inventor Robert C. Nickolson

Robert C. Nickolson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • D-homo steroids
    Patent number: 4033995
    Abstract: D-Homo-21-carboxylic acids of the formula ##STR1## the represents a single bond or a double bond; X is a hydrogen atom, a fluorine atom, or methylene;Y is a hydrogen atom, a fluorine atom, or a chlorine atom;Z is methylene, carbonyl, .beta.-hydroxymethylene, a .beta.-alkanoyloxymethylene or when Y is a chlorine atom, also .beta.-fluoromethylene or .beta.-chloromethylene;R.sub.1 is a hydrogen atom or methyl; andR.sub.2 is a hydrogen atom, hydroxy or alkanoyloxy; and their physiologically acceptable salts with bases and the 21-esters thereof, possess topical anti-inflammatory activity.
    Type: Grant
    Filed: September 2, 1975
    Date of Patent: July 5, 1977
    Assignee: Schering Aktiengesellschaft
    Inventors: Robert C. Nickolson, Ulrich Kerb, Rudolf Wiechert
  • Novel D-homo steroids
    Patent number: 4025563
    Abstract: D-homo steroids of the formula ##STR1## wherein X is H, F or CH.sub.3 ; Y is H, F or Cl; Z is CH.sub.2, CO, .beta.-HOCH.sub.2, .beta.-AcOCH.sub.2 or, when Y is Cl, also .beta.-FCH.sub.2 or .beta.-ClCH.sub.2 ; R.sub.1 is H or CH.sub.3, R.sub.2 is H, OH or AcO; and one of R.sub.3 and R.sub.4 is H and the other is OH or alkoxy or both are O, possess anti-inflammatory activity.
    Type: Grant
    Filed: September 2, 1975
    Date of Patent: May 24, 1977
    Assignee: Schering Aktiengesellschaft
    Inventors: Robert C. Nickolson, Ulrich Kerb, Rudolf Wiechert