Abstract: A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.

Abstract: A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.

Abstract: A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.

Abstract: Apparatus and method for harvesting energy from the environment and/or other external sources and converting it to useful electrical energy. The harvester does not contain a permanent magnet or other local field source but instead relies on the earth's magnetic field of another source of a magnetic field that is external to the sensing device. One advantage of these new harvesters is that they can be made smaller and lighter than energy harvesters that contain a magnet and/or an inertial mass.

Abstract: Apparatus and method for harvesting energy from the environment and/or other external sources and converting it to useful electrical energy. The harvester does not contain a permanent magnet or other local field source but instead relies on the earth's magnetic field of another source of a magnetic field that is external to the sensing device. One advantage of these new harvesters is that they can be made smaller and lighter than energy harvesters that contain a magnet and/or an inertial mass.

Abstract: Apparatus and method for harvesting energy from the environment and/or other external sources and converting it to useful electrical energy. The harvester does not contain a permanent magnet or other local field source but instead relies on the earth's magnetic field of another source of a magnetic field that is external to the sensing device. One advantage of these new harvesters is that they can be made smaller and lighter than energy harvesters that contain a magnet and/or an inertial mass.

Abstract: A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.

Abstract: Implantable electrical lead wires, such as cobalt-chromium-molybdenum alloy wires, are coated with a metal, ceramic, or carbon to a thickness of about 100 nm or less to provide a non-reactive interface to polyurethane sheathing materials. Preferred is sputter coating an amorphous carbon intermediate the alloy wire and the polyurethane sheath.

Abstract: High reliability electrical connections between a helical strand and flat electrodes, such us strip electrodes found in implantable neurostimulator system, are described. The connection consists of a crimp joint in which an inside diameter mandrel is used to provided the coil with sufficient radial rigidity to ensure structural integrity of the crimp. The mandrel is made of a relatively soft biocompatible material that deforms rather than damages the fine wires of the helical strand during crimping. The crimping is accomplished by radial deformation of an annular or semi-annular crimping member that receives the helical strand/mandrel assembly.

Abstract: A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.

Abstract: High reliability electrical connections between a helical strand and flat electrodes, such as strip electrodes found in implantable neurostimulator system, are described. The connection consists of a crimp joint in which an inside diameter mandrel is used to provide the coil with sufficient radial rigidity to ensure structural integrity of the crimp. The mandrel is made of a relatively soft biocompatible material that deforms rather than damages the fine wires of the helical strand during crimping. The crimp is accomplished by radial deformation of an annular or semi-annular crimping member that receives the helical strand/mandrel assembly.

Abstract: A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.

Abstract: Apparatus and method for wireless near-field magnetic communication (NFMC) of information (e.g., voice or data) over modest distances (centimeters to a few kilometers). The transmission can proceed from an inductive coil transmitter to a magneto-electric (ME) receiving device, or between two ME devices. Electrical power may also be transmitted from and/or received using the same device. In one case, power and data are transmitted from an induction coil to a distant ME device that collects power and transmits data back to the power-transmission coil. In another case, the wireless transfer of data can be carried out between two ME devices. ME devices can be engineered to transmit or receive data and to receive electric power over a variety of frequencies by changing their dimensions, their material makeup and configuration, electrode configurations, and/or their resonance modes (longitudinal, transversal, bending, shear etc).

Abstract: An inductive energy harvester comprises a permanent magnet magnetic field source attached by a pair of compact spiral disk springs to an induction coil. The springs position the magnet so that the induction coil surrounds one end of the magnet where the flux density is greatest. In addition, the magnetic flux emerging from that end of the magnet is enhanced by a disk of magnetic material having high permeability and high flux density. In another embodiment, the magnetic field source comprises two dipole magnets arranged in opposing flux relationship with a thin layer of high flux density, high magnetic permeability material located in a gap between the magnets.

Abstract: Small implantable magnetostrictive-electroactive (ME) device for delivering electrical energy to surrounding tissue. The wireless ME device is activated by a changing magnetic field from an externally applied alternating magnetic field source. The ME device provides a means for stimulating a nerve, tissue or internal organ with direct electrical current, such as relatively low-level direct current for temporary or as needed therapy. The field source (e.g. small coil antenna) may be a hand-held device or affixed to the wearer's skin, clothing or accessories. The ME implant may be configured as pellets which are small enough to be implanted through a surgical needle. In one embodiment, the wireless energy transmission system can be used for stimulating bone growth.

Abstract: A magnetic field sensor comprises one or more magnetic layers of magnetostrictive material that is mechanically bonded to one or more layers of electroactive material. When a magnetic field is applied to the device, it rotates the magnetization that is present in the in the magnetostrictive material thereby generating a magnetostrictive stress in the material. The magnetostrictive stress generated by this layer, in turn, stresses the piezoelectric layer to which the magnetostrictive layer is bonded. In order to increase sensitivity, the voltage across the piezoelectric material is measured in a direction that is parallel to the plane in which the magnetization in the magnetic material rotates.

Abstract: High reliability electrical connections between a helical strand and flat electrodes, such as strip electrodes found in implantable neurostimulator systems, are described. The connection consists of a crimp joint in which an inside diameter mandrel is used to provided the coil with sufficient radial rigidity to ensure structural integrity of the crimp. The mandrel is made of a relatively soft biocompatible material that deforms rather than damages the fine wires of the helical strand during crimping. The crimp is accomplished by radial deformation of an annular or semi-annular crimping member that receives the helical strand/mandrel assembly.

Abstract: A method of and an apparatus for measuring the thickness of one liquid layer overlying another liquid layer. The liquid thickness measuring device consists of a tubular casing, constructed of a transparent material, a resiliently biased valve member and a retaining member. The resiliently biased valve member is pivotally movable between open and closed positions to alternatively allow liquid to be sampled to enter the casing when in the open position and to seal the liquid sample when in the closed position. In operation, with the valve member disengaged from the bottom of the tubular casing, the measuring device is slowly lowered into the enclosed device. As a result, the liquid present in the enclosed structure is conductible through the opening of the tubular casing, to seek its level in the tubular member. The retaining member, which engages and holds the valve in an open position, is then released and the valve is allowed to move to the closed position.

Abstract: Coatings for implantable electrodes consisting of single- or multi-walled nanotubes, nanotube ropes, carbon whiskers, and a combination of these are described. The nanotubes can be carbon or other conductive nanotube-forming materials such as a carbon-doped boron nitride. The nanotube coatings are grown “in situ” on a catalytic substrate surface from thermal decomposition, or they are bonded to the substrate using a metal or conductive metal oxide thin film binder deposited by means of a metal compound precursor in liquid form. In the latter case, the precursor/nanotube coating is then converted to a pure metal or conductive metal oxide, resulting in the desired surface coating with imbedded nanotubes.

Abstract: Coatings for implantable electrodes such as pacing electrodes, neurostimulator electrodes, and electroporating electrodes and sensing electrodes are described. The coatings are highly biocompatible, having low polarization. They consist of a biocompatible, conductive substrate, such as of sintered platinum/10% iridium; a thin film outer layer of biocompatible, conductive carbon; and a biocompatible, conductive intermediate layer having a high surface area. The intermediate layer is preferably of sputtered titanium nitride and increases the surface area of the carbonaceous outer layer.