Abstract: A programmable actuator having multiple programmable functions is provided. The programmable actuator may be used on an off-board tool. In accordance with an embodiment, an off-board tool, OBT, including a user-defined programmable actuator is provided. In accordance with another embodiment, an OBT includes a processor, an internal memory, a programmable actuator, program logic and perform function logic. In accordance with yet another embodiment, a method of actuating performance of a user-defined series of functions for a OBT is provided. The method includes the step of actuating a programmable actuator of the OBT with a single actuating action.

Abstract: A programmable actuator having multiple programmable functions is provided. The programmable actuator may be used on an off-board tool. In accordance with an embodiment, an off-board tool, OBT, including a user-defined programmable actuator is provided. In accordance with another embodiment, an OBT includes a processor, an internal memory, a programmable actuator, program logic and perform function logic. In accordance with yet another embodiment, a method of actuating performance of a user-defined series of functions for a OBT is provided. The method includes the step of actuating a programmable actuator of the OBT with a single actuating action.

Abstract: A programmable actuator having multiple programmable functions is provided. The programmable actuator may be used on an off-board tool. In accordance with an embodiment, an off-board tool, OBT, including a user-defined programmable actuator is provided. In accordance with another embodiment, an OBT includes a processor, an internal memory, a programmable actuator, program logic and perform function logic. In accordance with yet another embodiment, a method of actuating performance of a user-defined series of functions for a OBT is provided. The method includes the step of actuating a programmable actuator of the OBT with a single actuating action.

Abstract: A programmable actuator having multiple programmable functions is provided. The programmable actuator may be used on an off-board tool. In accordance with an embodiment, an off-board tool, OBT, including a user-defined programmable actuator is provided. In accordance with another embodiment, an OBT includes a processor, an internal memory, a programmable actuator, program logic and perform function logic. In accordance with yet another embodiment, a method of actuating performance of a user-defined series of functions for a OBT is provided. The method includes the step of actuating a programmable actuator of the OBT with a single actuating action.

Abstract: A method for the synthesis of a plurality of oligonucleotides comprising the steps of(i) forming a first oligonucleotide on a first cleavable link attached to a solid support;(ii) attaching to the first oligonucleotide a cleavable linker moiety;(iii) forming a second oligonucleotide on the cleavable linker moiety; and(iv) cleaving the first cleavable link and the cleavable linker moiety to give a plurality of oligonucleotides; wherein the cleavable linker moiety is of the Formula (1): ##STR1## in which A.sup.1, A.sup.2 and E are as defined herein, and novel compounds which may be used in the operation of the method.

Abstract: A method for the synthesis of a plurality of oligonucleotides comprising the steps of(i) forming a first oligonucleotide on a first cleavable link attached to a solid support;(ii) attaching to the first oligonucleotide a cleavable linker moiety;(iii) forming a second oligonucleotide on the cleavable linker moiety; and(iv) cleaving the first cleavable link and the cleavable linker moiety to give a plurality of oligonucleotides; wherein the cleavable linker moiety is of the Formula (1): ##STR1## in which A.sup.1, A.sup.2 and E are as defined herein, and novel compounds which may be used in the operation of the method.

Abstract: New polymer supports containing cleavable cross-links are described which are suitable for solid phase peptide synthesis and can then be solublized for further chemical or biological manipulation (including immunization) in solution.

Abstract: The present invention relates to the synthesis of chemical compounds and more particularly to the synthesis of organic compounds, for example, peptides and oligonucleotides.The invention provides a composite material for use in the synthesis of organic compounds comprising a support material and, supported on the support material, an organic compound synthesizing substance.It is preferred that the organic compound synthesizing substance is a gel (e.g. a dimethylacrylamide co-polymer gel).The invention also provides a method for preparing a composite material for use in the synthesis of organic compounds and a method for the synthesis of organic compounds.