Abstract: A device for preventing contamination of a clean room during a drilling or cutting operation. A box-like chamber is provided for containing a power driven tool such as a drill. One wall of the chamber includes an opening for access to the workpiece (e.g. a wall to be cut or drilled). Another wall includes an access port with a rubber glove for operating the power tool. A pigtail electrical outlet within the chamber provides electrical power to the tool. A similar chamber may be used on an opposite side of the wall being drilled in the event it must be kept clean also. Both chambers include a port for attachment to a vacuum source such as a conventional vacuum cleaner and a port for entry of air to divert debris away from the workpiece and into the vacuum cleaner. In another embodiment, a small enclosure is clamped to the body of a drill or similar tool. The enclosure includes a vacuum port for removal of the debris.