Patents by Inventor Robert C. Williams, III

Robert C. Williams, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12023343
    Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: July 2, 2024
    Assignees: AustinPx, LLC, Board of Regents, The University of Texas System
    Inventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. Dinunzio, Robert O. Williams, III
  • Publication number: 20180228268
    Abstract: An apparatus for dispensing a fluid comprises a housing and a resilient liner adapted to hold the fluid disposed in the housing. A fluid transfer mechanism is in fluid communication between the liner and an applicator assembly mounted on the housing for dispensing the fluid on the skin of the user. The applicator assembly includes an actuator movable relative to the housing so as to activate the fluid transfer mechanism when the actuator is reciprocated. A fluid delivery element is held in contact against skin of a user for applying the fluid onto the skin. The fluid delivery element is supported on the actuator to be movable together with the actuator by varying contact pressure with the skin. Each movement of the actuator generates continuous negative pressure within the liner for drawing fluid through the fluid transfer mechanism and collapsing the liner.
    Type: Application
    Filed: March 6, 2018
    Publication date: August 16, 2018
    Inventors: Arianna Megaro, Matthew Megaro, Robert C. Williams, III, Brad Forrest, Matt Khare
  • Patent number: 9907384
    Abstract: An apparatus for dispensing a fluid comprises a housing and a resilient liner adapted to hold the fluid disposed in the housing. A fluid transfer mechanism is in fluid communication between the liner and an applicator assembly mounted on the housing for dispensing the fluid on the skin of the user. The applicator assembly includes an actuator movable relative to the housing so as to activate the fluid transfer mechanism when the actuator is reciprocated. A fluid delivery element is held in contact against skin of a user for applying the fluid onto the skin. The fluid delivery element is supported on the actuator to be movable together with the actuator by varying contact pressure with the skin. Each movement of the actuator generates continuous negative pressure within the liner for drawing fluid through the fluid transfer mechanism and collapsing the liner.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 6, 2018
    Assignee: BlokRok, Inc.
    Inventors: Arianna Megaro, Matthew Megaro, Robert C. Williams, III, Brad Forrest, Matt Khare
  • Publication number: 20160029770
    Abstract: An apparatus for dispensing a fluid comprises a housing and a resilient liner adapted to hold the fluid disposed in the housing. A fluid transfer mechanism is in fluid communication between the liner and an applicator assembly mounted on the housing for dispensing the fluid on the skin of the user. The applicator assembly includes an actuator movable relative to the housing so as to activate the fluid transfer mechanism when the actuator is reciprocated. A fluid delivery element is held in contact against skin of a user for applying the fluid onto the skin. The fluid delivery element is supported on the actuator to be movable together with the actuator by varying contact pressure with the skin. Each movement of the actuator generates continuous negative pressure within the liner for drawing fluid through the fluid transfer mechanism and collapsing the liner.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Arianna Megaro, Matthew Megaro, Robert C. Williams, III, Brad Forrest, Matt Khare
  • Patent number: 8926659
    Abstract: A barbed suture is disclosed having barbs defined by a variable-angle cut surface. A cutting bed supports the suture during cutting. A cutting device is moved through the suture thread along a selected path. The angle of the cutting device is changed during cutting so that there is a corresponding change in the angle of the cut surface which defines each barb. A cutting arm is articulated to allow change of the angle of the cutting device. The change in the angle of the cutting device is used to control the shape and depth of cut of the barbs.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: January 6, 2015
    Assignee: Ethicon, Inc.
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 8757914
    Abstract: An apparatus for dispensing a fluid comprises a housing and a resilient liner adapted to hold the fluid disposed in the housing. A fluid transfer mechanism is in fluid communication between the liner and an applicator assembly mounted on the housing for dispensing the fluid on the skin of the user. The applicator assembly includes an actuator movable relative to the housing so as to activate the fluid transfer mechanism when the actuator is reciprocated. A fluid delivery element is held in contact against skin of a user for applying the fluid onto the skin. The fluid delivery element is supported on the actuator to be movable together with the actuator by varying contact pressure with the skin. Each movement of the actuator generates continuous negative pressure within the liner for drawing fluid through the fluid transfer mechanism and collapsing the liner.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 24, 2014
    Assignee: BlokRok, Inc.
    Inventors: Arianna Megaro, Matthew Megaro, Robert C. Williams, III, Brad Forrest, Matt Khare
  • Patent number: 8032996
    Abstract: An apparatus for cutting barbs into a suture having a filament supply. The apparatus also has an in-feed collet for holding one end of a filament threaded therethrough. Further the apparatus has an out-feed collet for holding a second end of a filament threaded therethrough. Additionally, the apparatus has a holder positioned between said in-feed and out-feed collets for holding a filament suspended between the in-feed and out-feed collets. The apparatus also has a cutting assembly for cutting barbs in the filament tensioned between the in-feed and out-feed collets.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: October 11, 2011
    Inventors: Michael Trull, Perry A. Genova, Robert C. Williams, III, Jeffrey C. Leung, Matthew A. Megaro, Stanton Batchelor, Andrew Corson
  • Patent number: 8028388
    Abstract: A system for manufacturing self-retaining suture is disclosed. The system includes a cutting bed for creating and supporting a suture during cutting of tissue-grasping elements at different angular positions. A cutting device is moved through the suture thread along a path which can include longitudinal, transverse, oscillating and depth components to create a desired tissue-grasping element on the surface of the suture. The path of the cutting device and the rotation of the suture relative to the cutting device are controlled so that a plurality of angularly-displaced tissue-grasping elements can be created on the suture.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: October 4, 2011
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 8028387
    Abstract: A system for manufacturing self-retaining suture includes means for supporting the suture during cutting of retainers which protrude from the suture at multiple angles. The system includes an anvil having a channel configured to support a suture during cutting of a retainer at a first angular position while providing for non-interference between the anvil and retainers previously cut on the suture at one or more angular positions different than the first angular position. In embodiments the channel is provided with notches which receive previously-formed retainers during creation of subsequent retainers. The system thereby provides for rotating the suture and supporting the suture with the anvil without interference with previously-formed retainers.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: October 4, 2011
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 8020263
    Abstract: An automated system for manufacturing self-retaining suture is disclosed. The system includes a cutting bed to which a suture is mounted. A power-operated cutting arm moves a cutting device through the suture along a preselected path and at a preselected angle to create a tissue retainer having a desired geometry. An indexing mechanism moves the suture relative to the cutting device. The operation of the cutting arm in conjunction with the geometry of the cutting device and movement of the suture thread allows for creating a plurality of tissue retainers having a desired geometry distributed along the length of the suture thread.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: September 20, 2011
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 8015678
    Abstract: A method for manufacturing self-retaining suture is disclosed. The method provides for creating and supporting a suture during cutting of tissue-grasping elements at different angular positions. A cutting device is moved through the suture thread along a path which can include longitudinal, transverse, oscillating and depth components to create a desired tissue-grasping element on the surface of the suture. The path of the cutting device and the rotation of the suture relative to the cutting device are controlled so that a plurality of angularly-displaced tissue-grasping elements can be created on the suture.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: September 13, 2011
    Assignee: Quill Medical, Inc.
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 8011072
    Abstract: A method for manufacturing a self-retaining suture is disclosed. A cutting bed supports the suture during cutting. A cutting device is moved through the suture thread along a selected path. The angle of the cutting device is changed during cutting. A cutting arm is articulated to allow change of the angle of the cutting device. The change in the angle of the cutting device is used to control the depth of cut and/or elevate a tissue-retainer away from the suture to better engage tissue.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: September 6, 2011
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 7996968
    Abstract: An automated method for manufacturing self-retaining suture is disclosed. The suture is mounted to a support. A power-operated cutting arm moves a cutting device through the suture along a preselected path and at a preselected angle to create a tissue retainer having a desired shape and size. The suture is indexed relative to the cutting device. The operation of the cutting arm in conjunction with the geometry of the cutting device and linear advancement of the suture thread allows for creating a plurality of tissue-retainers having a desired geometry along the length of the suture thread.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: August 16, 2011
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 7996967
    Abstract: A system for manufacturing a self-retaining suture is disclosed. The system includes a cutting bed which supports the suture during cutting. A cutting device makes cuts in the suture thread having a preselected geometry. A cutting arm is articulated to allow change of the angle of the cutting device during cutting. The change in the angle of the cutting device is used to control the depth of cut and/or elevate a tissue-retainer away from the suture to better engage tissue.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: August 16, 2011
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 7980491
    Abstract: An improved atomization system for aerosolizing liquids including a vortexing nozzle and a flat or protruding face on the nozzle exit orifice. The system can also include a diverging mouthpiece insert. The present invention can produce a high fine particle fraction and modest throat deposition in conjunction with reduced aerosol plume velocity and impact force.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: July 19, 2011
    Assignee: Abbott Laboratories
    Inventors: Prashant P. Kakade, Robert C. Williams, III, Perry Genova
  • Publication number: 20110093010
    Abstract: A barbed suture is disclosed having barbs defined by a variable-angle cut surface. A cutting bed supports the suture during cutting. A cutting device is moved through the suture thread along a selected path. The angle of the cutting device is changed during cutting thereby changing the angle of the cut surface which defines each barb. A cutting arm is articulated to allow change of the angle of the cutting device. The change in the angle of the cutting device is used to control the shape and depth of cut of the barbs.
    Type: Application
    Filed: December 20, 2010
    Publication date: April 21, 2011
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Patent number: 7913365
    Abstract: A method of making a barbed suture by varying the blade geometry and/or the movement of the blade when cutting a suture is disclosed. The method can also be accomplished with a cutting device to create a plurality of barbs on the exterior of surgical suture. The barbs produced using the method with the cutting device can be the same or random configurations.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: March 29, 2011
    Inventors: Perry A. Genova, Robert C. Williams, III, Warren Jewett, Matthew A. Megaro
  • Publication number: 20100313730
    Abstract: An automated system for manufacturing self-retaining suture is disclosed. The system includes a cutting bed to which a suture is mounted. A power-operated cutting arm moves a cutting device through the suture along a preselected path and at a preselected angle to create a tissue retainer having a desired geometry. An indexing mechanism moves the suture relative to the cutting device. The operation of the cutting arm in conjunction with the geometry of the cutting device and movement of the suture thread allows for creating a plurality of tissue retainers having a desired geometry distributed along the length of the suture thread.
    Type: Application
    Filed: August 4, 2010
    Publication date: December 16, 2010
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Publication number: 20100313723
    Abstract: A system for manufacturing self-retaining suture is disclosed. The system includes a cutting bed for creating and supporting a suture during cutting of tissue-grasping elements at different angular positions. A cutting device is moved through the suture thread along a path which can include longitudinal, transverse, oscillating and depth components to create a desired tissue-grasping element on the surface of the suture. The path of the cutting device and the rotation of the suture relative to the cutting device are controlled so that a plurality of angularly-displaced tissue-grasping elements can be created on the suture.
    Type: Application
    Filed: August 4, 2010
    Publication date: December 16, 2010
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett
  • Publication number: 20100313729
    Abstract: A method for manufacturing self-retaining suture includes supporting the suture during cutting of retainers at multiple angles. The method utilizes an anvil having a channel configured to support a suture during cutting of a barb at a first angular position while providing for non-interference between the anvil and barbs previously cut on the suture at one or more angular positions different than the first angular position. In embodiments the channel is provided with notches which receive previously-formed barbs during creation of subsequent barbs. Thus the method provides for rotating the suture and then supporting the suture with the anvil without interference with previously formed retainers.
    Type: Application
    Filed: August 4, 2010
    Publication date: December 16, 2010
    Inventors: Perry Genova, Robert C. Williams, III, Warren Jewett