Abstract: The present invention relates to novel linkers containing a 2,3-disubstituted succinic group, or 2-monosubstituted, or 2,3-disubstituted fumaric or maleic (trans (E)- or cis (Z)-butenedioic), or acetylenedicarboxyl group for conjugation of a cytotoxic agent, and/or one or more different functional molecules per linker to a cell-binding molecule, through bridge linking pairs of thiols on the cell-binding molecule specifically. The invention also relates to methods of making such linkers, and of using such linkers in making homogeneous conjugates, as well as of application of the conjugates in treatment of cancers, infections and autoimmune disorders.

Abstract: The invention provides an open gear lubricant composition containing a blend of ethylene-propylene copolymers and a metallic soap thickener. The blend of ethylene-propylene copolymers includes a first ethylene-propylene copolymer having a kinematic viscosity at 100° C. of 80 centistokes to 220 centistokes and a second ethylene-propylene copolymer having a kinematic viscosity at 100° C. 500 centistokes to 3000 centistokes. The invention further relates to a method of lubricating a mechanical device with the open gear lubricant composition.

Abstract: A coated textured glass article is described herein that comprises: a glass body comprising a first surface; a plurality of polyhedral surface features extending from the first surface; and a coating disposed on the first surface of the body and the plurality of polyhedral surface features. Each of the plurality of polyhedral surface features comprises a base on the first surface and a plurality of facets extending from the base and converging toward one another. The coating comprises a multilayer interference stack.

Abstract: Various technologies described herein pertain to a sensor for an autonomous vehicle that includes one or more heat dissipation features. A sensor includes a top cover and a bottom cover, where the top cover and the bottom cover form at least a portion of a casing of the sensor. The sensor includes a coldplate, a first printed circuit board, and a second printed circuit board. A top side of the first printed circuit board is coupled to the top cover and a bottom side of the first printed circuit board is coupled to a top side of the coldplate. A top side of the second printed circuit board is coupled to a bottom side of the coldplate and a bottom side of the second printed circuit board is coupled to the bottom cover. Various features described herein enhance heat transfer from components on the first and second printed circuit boards.

Abstract: An example automated driving system computer can include a board, one or more processors coupled to the board, a first layer of a first thermal interface material applied on the one or more processors, a heat spreader having a first side and a second side, the first side in contact with the first layer of the first thermal interface material, a second layer of a second thermal interface material applied on the second side of the heat spreader, and a cold plate in contact with the second layer of the second thermal interface material.

Abstract: An example sensor bracket assembly can include one or more cold plates forming a core bracket structure, wherein the core bracket structure and the one or more cold plates provide structural support for the sensor bracket assembly; a housing enclosing the core bracket structure; one or more sensor mounts for mounting one or more sensors on the sensor bracket assembly; and one or more attachment portions for attaching the sensor bracket assembly to a body of a vehicle.

Abstract: The subject disclosure relates to a water-tight sealed stud assembly for high current applications. The water-tight sealed stud assembly can include a stud, a sealing ring, a sleeve, and a body. The stud may have a stud base and a thickened portion having an annular groove. The sealing ring may be disposed in the annular groove. The sleeve may be disposed circumferentially around the stud and made of a conductive material. The body may be disposed circumferentially around the sleeve and made of a non-conductive material. Systems and methods are also provided.

Abstract: Various technologies described herein pertain to a sensor for an autonomous vehicle that includes one or more heat dissipation features. A sensor includes a top cover and a bottom cover, where the top cover and the bottom cover form at least a portion of a casing of the sensor. The sensor includes a coldplate, a first printed circuit board, and a second printed circuit board. A top side of the first printed circuit board is coupled to the top cover and a bottom side of the first printed circuit board is coupled to a top side of the coldplate. A top side of the second printed circuit board is coupled to a bottom side of the coldplate and a bottom side of the second printed circuit board is coupled to the bottom cover. Various features described herein enhance heat transfer from components on the first and second printed circuit boards.

Abstract: An example sensor bracket assembly can include one or more cold plates forming a core bracket structure, wherein the core bracket structure and the one or more cold plates provide structural support for the sensor bracket assembly; a housing enclosing the core bracket structure; one or more sensor mounts for mounting one or more sensors on the sensor bracket assembly; and one or more attachment portions for attaching the sensor bracket assembly to a body of a vehicle.

Abstract: Two-phase cooling systems for autonomous driving super computers (ADSC) are described herein. In some examples, a two-phase cooling system can include a flow channel configured to circulate a flow; an evaporative heat exchanger comprising an inlet for receiving fluid from the flow channel and an outlet for releasing vapor generated from the fluid, the evaporative heat exchanger being configured to collect heat from components of the ADSC and transfer the heat away via the vapor released from the first outlet; a condensing heat exchanger configured to condense the vapor and remove latent heat associated with the vapor, the condensing heat exchanger comprising an inlet to the flow channel for receiving the vapor and an outlet to the flow channel for discharging fluid generated by condensing the vapor; and a pump configured to receive the fluid from the condensing heat exchanger and circulate the fluid to the evaporative heat exchanger.

Abstract: The subject disclosure relates to a water-tight sealed stud assembly for high current applications. The water-tight sealed stud assembly can include a stud, a sealing ring, a sleeve, and a body. The stud may have a stud base and a thickened portion having an annular groove. The sealing ring may be disposed in the annular groove. The sleeve may be disposed circumferentially around the stud and made of a conductive material. The body may be disposed circumferentially around the sleeve and made of a non-conductive material. Systems and methods are also provided.

Abstract: An example automated driving system computer can include a board, one or more processors coupled to the board, a first layer of a first thermal interface material applied on the one or more processors, a heat spreader having a first side and a second side, the first side in contact with the first layer of the first thermal interface material, a second layer of a second thermal interface material applied on the second side of the heat spreader, and a cold plate in contact with the second layer of the second thermal interface material.

Abstract: Two-phase cooling systems for autonomous driving super computers (ADSC) are described herein. In some examples, a two-phase cooling system can include a flow channel configured to circulate a flow; an evaporative heat exchanger comprising an inlet for receiving fluid from the flow channel and an outlet for releasing vapor generated from the fluid, the evaporative heat exchanger being configured to collect heat from components of the ADSC and transfer the heat away via the vapor released from the first outlet; a condensing heat exchanger configured to condense the vapor and remove latent heat associated with the vapor, the condensing heat exchanger comprising an inlet to the flow channel for receiving the vapor and an outlet to the flow channel for discharging fluid generated by condensing the vapor; and a pump configured to receive the fluid from the condensing heat exchanger and circulate the fluid to the evaporative heat exchanger.

Abstract: A method of rendering a graphical object (e.g., 801) on a page (800), is disclosed. A region of the page containing the graphical object (801) is marked as output incompatible based on the graphical object (801) being output incompatible. A bounding box comprising the marked region is determined. A proportion of a number of the regions marked as output incompatible are determined to a total number of regions in the bounding box. A further region within the bounding box is marked as output incompatible to increase the determined proportion above a threshold. The graphical object in the marked region and the further marked region is converted into an output compatible graphical object if the determined proportion is above the threshold. The output compatible graphical object is rendered.

Abstract: A method of rendering a graphical object (e.g., 801) on a page (800), is disclosed. A region of the page containing the graphical object (801) is marked as output incompatible based on the graphical object (801) being output incompatible. A bounding box comprising the marked region is determined. A proportion of a number of the regions marked as output incompatible are determined to a total number of regions in the bounding box. A further region within the bounding box is marked as output incompatible to increase the determined proportion above a threshold. The graphical object in the marked region and the further marked region is converted into an output compatible graphical object if the determined proportion is above the threshold. The output compatible graphical object is rendered.

Abstract: A method for generating an outline for a stroked line of specified width from an input line (601) defined by a vector having two input points (P0, P1) is disclosed. The method comprises the steps of: determining an offset vector based on the vector, the offset vector having components [Xoff, Yoff]; determining a first set of two pairs of points (L1, L2 and R1, R2) based on the offset vector applied to the two input points (P0, P1); and determining a second set of two pairs of points (L0, L3 and R0, R3) based on the first set of points (L1, L2 and R1, R2). The second set of two pairs of points (L0, L3 and R0, R3) defines at least a portion of the outline and one of the components of the offset vector [Xoff, Yoff] is independent of the inclination of the vector and the specified width.

Abstract: A method of rendering a graphical object (e.g., 801) on a page (800), is disclosed. A region of the page containing the graphical object (801) is marked as output incompatible based on the graphical object (801) being output incompatible. A bounding box comprising the marked region is determined A proportion of a number of the regions marked as output incompatible are determined to a total number of regions in the bounding box. A further region within the bounding box is marked as output incompatible to increase the determined proportion above a threshold. The graphical object in the marked region and the further marked region is converted into an output compatible graphical object if the determined proportion is above the threshold. The output compatible graphical object is rendered.

Abstract: A method of modifying drawing commands to be input to a rendering process is disclosed. The method detects a first glyph drawing command and detects a predetermined number of further glyph drawing commands proximate within a threshold of the first glyph drawing command. The predetermined number of proximate glyph drawing commands is accumulated. The accumulated proximate glyph drawing commands are combined into a 1-bit depth bitmap. The 1-bit depth bitmap is output to the rendering process as a new drawing command.

Abstract: A method is described for determining a discrete boundary for an object to be rendered into a raster pixel image having a plurality of scanlines. In the method, the object is rotated by an integer multiple of 90 degrees, and an outline of the rotated object is decomposed into line segments. For each scanline to be rendered, points of intersection between the line segments and the scanline are determined, and each point of intersection is rounded to an adjacent position selected from a finite set of positions on the scanline using a rule chosen according to the amount of rotation. The rounded points of intersection delimiting the discrete boundary. If the object is rotated by odd multiple of 90 degrees the method includes the steps of identifying points of intersection that satisfy a predetermined criterion; and shifting the identified points of intersection prior to rounding.

Abstract: A method for generating an outline for a stroked line of specified width from an input line (601) defined by a vector having two input points (P0, P1) is disclosed. The method comprises the steps of: determining an offset vector based on the vector, the offset vector having components [Xoff, Yoff]; determining a first set of two pairs of points (L1, L2 and R1, R2) based on the offset vector applied to the two input points (P0, P1); and determining a second set of two pairs of points (L0, L3 and R0, R3) based on the first set of points (L1, L2 and R1, R2). The second set of two pairs of points (L0, L3 and R0, R3) defines at least a portion of the outline and one of the components of the offset vector [Xoff, Yoff] is independent of the inclination of the vector and the specified width.