Abstract: A wearable display system includes one or more emissive micro-displays, e.g., micro-LED displays. The micro-displays may be monochrome micro-displays or full-color micro-displays. The micro-displays may include arrays of light emitters. Light collimators may be utilized to narrow the angular emission profile of light emitted by the light emitters. Where a plurality of emissive micro-displays is utilized, the micro-displays may be positioned at different sides of an optical combiner, e.g., an X-cube prism which receives light rays from different micro-displays and outputs the light rays from the same face of the cube. The optical combiner directs the light to projection optics, which outputs the light to an eyepiece that relays the light to a user's eye. The eyepiece may output the light to the user's eye with different amounts of wavefront divergence, to place virtual content on different depth planes.

Abstract: The invention describes transdermal vaccines which contain ultrasound responsive particles comprising a polypeptide shell. The surface of the particle has one or more indentations which are generally able to entrap a gas bubble. The particles are capable of generating inertial cavitation on exposure to ultrasound. The particles can be delivered transdermally, and can comprise antigen protein and/or adjuvant within the particle structure. The particles are therefore useful in methods of vaccination using transdermal delivery routes.

Abstract: The invention describes particles having a polypeptide shell. The polypeptide shell comprises at least one immunomodulatory polypeptide. Particles may be ultrasound-responsive particles, providing the ability to administer particles trandermally, or deliver particles to selected sites by use of ultrasound. Administration of the particles generates immunologic response to the polypeptide in the shell of the particle. The particles are therefore useful in methods of immunotherapy.

Abstract: The invention describes vaccine compositions containing particles having a polypeptide shell and a water-immiscible core. The polypeptide shell may comprise one or more pathogenic antigen proteins and/or one or more adjuvant polypeptides. Administration of the composition generates an immune response to the polypeptide contained in the shell. Adjuvant may be comprised in the water-immiscible core of the particle. The particles are therefore useful in methods of vaccination.

Abstract: A wearable display system includes a light projection system having one or more emissive microdisplays, e.g., micro-LED displays. The light projection system projects time-multiplexed left-eye and right-eye images, which pass through an optical router having a polarizer and a switchable polarization rotator. The optical router is synchronized with the generation of images by the light projection system to impart a first polarization to left-eye images and a second different polarization to right-eye images. Light of the first polarization is incoupled into an eyepiece having one or more waveguides for outputting light to one of the left and right eyes, while light of the second polarization may be incoupled into another eyepiece having one or more waveguides for outputting light to the other of the left and right eyes. Each eyepiece may output incoupled light with variable amounts of wavefront divergence, to elicit different accommodation responses from the user's eyes.

Abstract: A method and apparatus for generating plasmas adapted for chemical vapor deposition, etching and other operations, and in particular to the deposition of large-area diamond films, wherein a chamber defined by sidewalls surrounding a longitudinal axis is encircled by an axially-extending array of current-carrying conductors that are substantially transverse to the longitudinal axis of the chamber, and a gaseous material is provided in the chamber. A high-frequency current is produced in the conductors to magnetically induce ionization of the gaseous material in the chamber and form a plasma sheath that surrounds and extends along the longitudinal axis and conforms to the sidewalls of the chamber. A work surface extending in the direction of the longitudinal axis of the chamber is positioned adjacent a sidewall, exposed to the plasma sheath and treated by the plasma.

Abstract: A method and apparatus for generating plasmas adapted for chemical vapor deposition, etching and other operations, and in particular to the deposition of large-area diamond films, wherein a chamber defined by sidewalls surrounding a longitudinal axis is encircled by an axially-extending array of current-carrying conductors that are substantially transverse to the longitudinal axis of the chamber, and a gaseous material is provided in the chamber. A high-frequency current is produced in the conductors to magnetically induce ionization of the gaseous material in the chamber and form a plasma sheath that surrounds and extends along the longitudinal axis and conforms to the sidewalls of the chamber. A work surface extending in the direction of the longitudinal axis of the chamber is positioned adjacent a sidewall, exposed to the plasma sheath and treated by the plasma.

Abstract: A smoker's pipe has a plastics bowl (17) and stem (16) and, within the bowl, a ceramic liner (18) having a flange (19) which overlies the rim of the bowl, and is secured thereto by a resilient ring (29) of adhesive.