Abstract: Embryo genetic screening is performed by optical inspection, such as receiving, from an image sensor, image data representing emerging polarized light that has traversed a specimen, determining birefringence properties of the specimen based at least in part on the image data, generating a polarized light image representative of the specimen based at least in part on the birefringence properties, classifying features of the polarized light image using a classifier, identifying features of the polarized light image as mitotic spindles, determining mitotic activity of the specimen based at least in part on the identified mitotic spindles, and predicting a ploidy status of the specimen based on the mitotic activity.

Abstract: A system for producing multiple-pane insulating glazing units can include a conveyor and a plurality of laterally spaced-apart processing stations that are movable transversely relative to the longitudinally extending conveyor line. Each processing station may assemble glazing panes and a glazing spacer into a partially fabricated glazing unit, deliver insulative gas to a between-pane space between the glazing panes, and press the partially fabricated glazing unit together to seal the insulative gas in the between-pane space and form the multiple-pane insulating glazing unit. In some examples, each processing station moves to an alignment position with the conveyor to load glazing panes and a glazing spacer and then performs individual fabrication steps while offset from the conveyor. During this time, a different processing station can be aligned with the conveyor to unload a fabricated multiple-pane insulating glazing units and/or load unassembled glazing panes and a glazing spacer.

Abstract: A system for producing multiple-pane insulating glazing units can include a conveyor and a plurality of laterally spaced-apart processing stations that are movable transversely relative to the longitudinally extending conveyor line. Each processing station may assemble glazing panes and a glazing spacer into a partially fabricated glazing unit, deliver insulative gas to a between-pane space between the glazing panes, and press the partially fabricated glazing unit together to seal the insulative gas in the between-pane space and form the multiple-pane insulating glazing unit. In some examples, each processing station moves to an alignment position with the conveyor to load glazing panes and a glazing spacer and then performs individual fabrication steps while offset from the conveyor. During this time, a different processing station can be aligned with the conveyor to unload a fabricated multiple-pane insulating glazing units and/or load unassembled glazing panes and a glazing spacer.

Abstract: The invention provides machines for removing strips of masking from glazing panes. Also provided are methods of removing strips of masking from glazing panes. One embodiment of a machine for removing strips of masking material from a glazing pane includes a cutting head and a processing station. The processing station can be constructed to retain the glazing pane in a processing position with a first surface of the glazing pane oriented toward the cutting head. The cutting head can be movable in various directions across the masked glazing pane and include cutters to cut strips from the masking material.

Abstract: The invention provides machines for removing strips of masking from glazing panes. Also provided are methods of removing strips of masking from glazing panes.

Abstract: A system for producing multiple-pane insulating glazing units can include a conveyor and a plurality of laterally spaced-apart processing stations that are movable transversely relative to the longitudinally extending conveyor line. Each processing station may assemble glazing panes and a glazing spacer into a partially fabricated glazing unit, deliver insulative gas to a between-pane space between the glazing panes, and press the partially fabricated glazing unit together to seal the insulative gas in the between-pane space and form the multiple-pane insulating glazing unit. In some examples, each processing station moves to an alignment position with the conveyor to load glazing panes and a glazing spacer and then performs individual fabrication steps while offset from the conveyor. During this time, a different processing station can be aligned with the conveyor to unload a fabricated multiple-pane insulating glazing units and/or load unassembled glazing panes and a glazing spacer.

Abstract: The invention provides masking machines for applying masking to glazing panels. Also provided are methods of applying masking to glazing panels.

Abstract: The invention provides masking machines for applying masking to glazing panels. Also provided are methods of applying masking to glazing panels.

Abstract: A system for producing multiple-pane insulating glazing units can include a conveyor and a plurality of laterally spaced-apart processing stations that are movable transversely relative to the longitudinally extending conveyor line. Each processing station may assemble glazing panes and a glazing spacer into a partially fabricated glazing unit, deliver insulative gas to a between-pane space between the glazing panes, and press the partially fabricated glazing unit together to seal the insulative gas in the between-pane space and form the multiple-pane insulating glazing unit. In some examples, each processing station moves to an alignment position with the conveyor to load glazing panes and a glazing spacer and then performs individual fabrication steps while offset from the conveyor. During this time, a different processing station can be aligned with the conveyor to unload a fabricated multiple-pane insulating glazing units and/or load unassembled glazing panes and a glazing spacer.

Abstract: The present invention provides an improved method to deliver estrogen to menopausal women comprising administering ultra-low dose estradiol alternating with standard-dose estradiol.

Abstract: A system is provided that includes a party file having a plurality of party records with each of the plurality of party records having party information relating to one of a plurality of parties. Also included is an account file having a plurality of account records with each of the plurality of account records having account information relating to one of a plurality of accounts. Each of the plurality of account records also includes a link to at least one of the plurality of party records. Finally, a transaction file is included having a plurality of transaction records with each of the plurality of transaction records having transaction information relating to one of a plurality of transactions. Each of the plurality of transaction records includes a link to one of the plurality of account records.

Abstract: The invention relates to detection of individuals having or at risk of developing endometriosis based on the presence of one or more polymorphism in a gene associated with the fibrinolytic pathway, and methods for treating or preventing endometriosis by modulating the fibrinolytic pathway.

Abstract: A method of maintaining circadian rhythm of a subject comprising selectively substantially blocking retinal exposure of the subject to light having a wavelength shorter than a specified wavelength during the night, and an apparatus for carrying out the claimed method comprising an optical filter that selectively at least substantially blocks light having a wavelength shorter than the specified wavelength.

Abstract: The invention relates to methods for producing endothelial cells, pericytes and/or muscle cells (in particular smooth muscle cells), cell preparations and pharmaceutical compositions comprising the cells or preparations, and the use of the cells, preparations and compositions in research or commercial applications. In aspects, the invention provides a method of treating a patient with a condition involving endothelial cells, endothelial precursor cells, pericytes and/or muscle cells, such as a peripheral vascular disease, comprising administering to the patient endothelial precursor cells, endothelial cells, pericytes and/or muscle cells obtained from multipotent CD45+HLA-ABC+Lin? cells.

Abstract: The invention relates to cellular compositions comprising hematopoietic cells with the potential or increased potential to form non-hematopoietic cells; methods for producing such cellular compositions; methods for differentiation of cells of cellular compositions of the invention into cells that exhibit morphological, physiological, functional, and/or immunological features of non-hematopoietic cells; and uses of the cellular compositions. The invention also relates to a method for the expansion of hematopoietic stem and progenitor cells.

Abstract: A system is provided that includes a party file having a plurality of party records with each of the plurality of party records having party information relating to one of a plurality of parties. Also included is an account file having a plurality of account records with each of the plurality of account records having account information relating to one of a plurality of accounts. Each of the plurality of account records also includes a link to at least one of the plurality of party records. Finally, a transaction file is included having a plurality of transaction records with each of the plurality of transaction records having transaction information relating to one of a plurality of transactions. Each of the plurality of transaction records includes a link to one of the plurality of account records.

Abstract: The invention relates to cellular compositions comprising hematopoietic cells with the potential or increased potential to form non-hematopoietic cells; methods for producing such cellular compositions; methods for differentiation of cells of cellular compositions of the invention into cells that exhibit morphological, physiological, functional, and/or immunological features of non-hematopoietic cells; and uses of the cellular compositions. The invention also relates to a method for the expansion of hematopoietic stem and progenitor cells.

Abstract: The invention relates to compositions and methods for enhancing the developmental potential of oocytes or preimplantation embryos by modulating mitochondrial-associated proteins and/or genomic integrity modifier proteins in the oocytes or preimplantation embryos. In one aspect of the invention, the levels of one or more mitochondrial-associated proteins and/or genomic integrity modifier proteins are increased, in particular by introducing the mitochondrial-associated proteins and/or genomic integrity modifier proteins into the oocytes or preimplantation embryos. Oocytes may be fertilized to obtain a zygote with increased levels of one or more mitochondrial-associated proteins and/or genomic integrity modifier proteins. The methods and compositions may be used to improve in vitro fertilization and embryo transfer methods, and nuclear transfer techniques.

Abstract: The present invention provides a device for inhibiting melatonin suppressing light from reaching the retina. The device having means for selectively blocking light having a wavelength capable of suppressing melatonin production in a human.

Abstract: A method of maintaining circadian rhythm of a subject comprising selectively substantially blocking retinal exposure of the subject to light having a wavelength shorter than a specified wavelength during the night, and an apparatus for carrying out the claimed method comprising an optical filter that selectively at least substantially blocks light having a wavelength shorter than the specified wavelength.