Patents by Inventor Robert Chesnut

Robert Chesnut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inducing cellular immune responses to prostate cancer antigens using peptide and nucleic acid compositions
    Publication number: 20070020327
    Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare prostate cancer-associated antigen epitopes, and to develop epitope-based vaccines directed towards prostate tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
    Type: Application
    Filed: May 5, 2006
    Publication date: January 25, 2007
    Inventors: John Fikes, Alessandro Sette, John Sidney, Scott Southwood, Robert Chesnut, Esteban Celis, Elissa Keogh
  • Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
    Publication number: 20070014810
    Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare human papillomavirus (HPV) epitopes, and to develop epitope-based vaccines directed towards HPV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HPV infection.
    Type: Application
    Filed: January 3, 2005
    Publication date: January 18, 2007
    Inventors: Denise Baker, Scott Power, Mark Newman, Robert Chesnut, Scott Southwood, Bianca Mothe, Manley Huang, Lilia Babe, Lawrence DeYoung, Yiyou Chen
  • Peptides for inducing a CTL and/or HTL response to hepatitis C virus
    Publication number: 20060093617
    Abstract: The present invention is directed to peptides, and nucleic acids encoding them, derived from the Hepatitis C Virus (HCV). The peptides are those which elicit a CTL and/or HTL response in a host. The invention is also directed to compositions and vaccines for prevention and treatment of HCV infection and diagnostic methods for detection of HCV exposure in patients.
    Type: Application
    Filed: May 31, 2005
    Publication date: May 4, 2006
    Applicants: Innogenetics, N.V., EPIMMUNE INC.
    Inventors: Marie-Ange Buyse, Geert Maertens, Erik Depla, Ignace Lasters, Johan Desmet, Denise Baker, Robert Chesnut, Mark Newman, Alessandro Sette, John Sidney, Scott Southwood
  • Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
    Patent number: 7026443
    Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare human papillomavirus (HPV) epitopes, and to develop epitope-based vaccines directed towards HPV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HPV infection.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: April 11, 2006
    Assignee: Epimmune Inc.
    Inventors: Alessandro Sette, John Sidney, Scott Southwood, Robert Chesnut, Esteban Celis, Howard M. Grey
  • Inducing cellular immune responses to human immunodeficiency virus-1 using peptide and nucleic acid compositions
    Publication number: 20050271676
    Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare human immunodeficiency virus (HIV) epitopes, and to develop epitope-based vaccines directed towards HIV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HIV infection.
    Type: Application
    Filed: January 28, 2005
    Publication date: December 8, 2005
    Inventors: Alessandro Sette, John Sidney, Scott Southwood, Brian Livingston, Robert Chesnut, Denise Baker, Esteban Celis, Ralph Kubo, Howard Grey
  • Inducing cellular immune responses to p53 using peptide and nucleic acid compositions
    Publication number: 20050196403
    Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare p53 epitopes, and to develop epitope-based vaccines directed towards p53-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
    Type: Application
    Filed: February 7, 2005
    Publication date: September 8, 2005
    Inventors: John Fikes, Alessandro Sette, John Sidney, Scott Southwood, Robert Chesnut, Esteban Celis, Elissa Keogh
  • Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions
    Publication number: 20050063983
    Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to develop epitope-based vaccines directed towards HBV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HBV infection.
    Type: Application
    Filed: September 4, 2003
    Publication date: March 24, 2005
    Inventors: Alessandro Sette, John Sidney, Scott Southwood, Maria Vitiello, Brian Livingston, Esteban Celis, Ralph Kubo, Howard Grey, Robert Chesnut
  • Method and system for optimizing multi-epitope nucleic acid constructs and peptides encoded thereby
    Publication number: 20040248113
    Abstract: The invention relates to the field of biology. In particular, the invention relates to a method and system for designing optimized multi-epitope vaccines having selected combinations of spacer nucleic acid at the junctions of the multi-epitope constructs encoding a plurality of CTL and/or HTL eoutioe oeotudes so as to minimize the number of junciontal epitopes and provide vaccines with increased immunogenicity.
    Type: Application
    Filed: June 8, 2004
    Publication date: December 9, 2004
    Inventors: Alessandro Sette, Robert Chesnut, Brian D Livingston, Denise Marie Baker, Mark J Newman, David H Brown
  • Inducing cellular immune responses to carcinoembryonic antigen using peptide and nucleic acid compositions
    Publication number: 20040146519
    Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare carcino-embryonic antigen (CEA) epitopes, and to develop epitope-based vaccines directed towards CEA-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
    Type: Application
    Filed: October 22, 2002
    Publication date: July 29, 2004
    Inventors: John Fikes, Alessandro Sette, John Sidney, Scott Southwood, Robert Chesnut, Esteban Celis, Elissa Keogh
  • Inducing cellular immune responses to her2/neu using peptide and nucleic acid compositions
    Publication number: 20040121946
    Abstract: This invention uses our knoeledge of the mechanisms by which antigen is recognized by T cells to identify and prepare HER2/neu epitopes, and to develop epitope-based vaccines directed towards HERS2/neu-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
    Type: Application
    Filed: October 24, 2002
    Publication date: June 24, 2004
    Inventors: John Fikes, Alessandro Sette, John Sydney, Scott Southwood, Robert Chesnut, Esteban Celis, Elissa Keogh
  • Inducing cellular immune responses to mage2/3 using peptide and nucleic acid compositions
    Publication number: 20040053822
    Abstract: The invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare MAGE2/3 epitopes, and to develop epitope-based vaccines directed towards MAGE2/3-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use it) the prevention and treatment of cancer.
    Type: Application
    Filed: October 21, 2002
    Publication date: March 18, 2004
    Inventors: John Fikes, Alessandro Sette, John Sidney, Scott Southwood, Robert Chesnut, Esteban Celis, Elissa Keogh
  • Inducing cellular immune responses to p53 using peptide and nucleic acid compositions
    Publication number: 20040048790
    Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare p53 epitopes, and to develop epitope-based vaccines directed towards p53-bearing tumors. More specifically, this application communicates our discovery of pharmnaceutical compositions and methods of use in the prevention and treatment of cancer.
    Type: Application
    Filed: November 18, 2002
    Publication date: March 11, 2004
    Inventors: John Fikes, Alessandro Sette, John Sidney, Scott Southwood, Robert Chesnut, Esteban Celis, Elissa Keogh
  • Inducing cellular immune responses to her2/neu using peptide and nucleic acid compositions
    Publication number: 20040018971
    Abstract: This invention uses our knoeledge of the mechanisms by which antigen is recognized by T cells to identify and prepare HER2/neu epitopes, and to develop epitope-based vaccines directed towards HERS2/neu-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
    Type: Application
    Filed: October 24, 2002
    Publication date: January 29, 2004
    Inventors: John Fikes, Alessandro Sette, John Sydney, Scott Southwood, Robert Chesnut, Esteban Celis, Elissa Keogh
  • HLA class I A2 tumor associated antigen peptides and vaccine compositions
    Patent number: 6602510
    Abstract: A composition or vaccine composition comprising eight isolated epitopes consisting of YLSGANLNV (SEQ. ID. NO: 1), IMIGVLVGV (SEQ. ID. NO: 2), KLBPVQLWV (SEQ. ID. NO: 3), SMPPPGTRV (SEQ. ID. NO: 4), KVAELVHFL (SEQ. ID. NO: 5), YLQLVFGIEV (SEQ. ID. NO: 6), RLLQETELV (SEQ. ID. NO: 7), and, VVLGVVFGI (SEQ. ID. NO: 8).
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: August 5, 2003
    Assignee: Epimmune Inc.
    Inventors: John D. Fikes, Alessandro Sette, John Sidney, Scott Southwood, Esteban Celis, Elissa A. Keogh, Robert Chesnut
  • Method and system for optimizing minigenes and peptides encoded thereby
    Publication number: 20020119127
    Abstract: The invention relates to the field of biology. In particular, the invention relates to a method and system for designing optimized multi-epitope vaccines having selected combinations of amino acid insertions at the junctions of the multi-epitope constructs so as to minimize the number of junctional epitopes and provide vaccines with increased immunogenicity.
    Type: Application
    Filed: June 27, 2001
    Publication date: August 29, 2002
    Inventors: Alessandro Sette, Robert Chesnut, Brian D. Livingston, Denise Marie Baker, Mark J. Newman, David H. Brown