Patents by Inventor Robert Chung-Huan Liu

Robert Chung-Huan Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical, compositions containing substituted 4'-hydroxyphenyl guanidines and methods of using same
    Patent number: 4109014
    Abstract: Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
    Type: Grant
    Filed: January 25, 1977
    Date of Patent: August 22, 1978
    Assignee: Armour Pharmaceutical Company
    Inventors: Robert Chung-Huan Liu, John Lawrence Hughes
  • Substituted 4-hydroxyphenyl guanidines
    Patent number: 4060554
    Abstract: Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be activate as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
    Type: Grant
    Filed: January 25, 1977
    Date of Patent: November 29, 1977
    Assignee: Armour Pharmaceutical Company
    Inventors: Robert Chung-Huan Liu, John Lawrence Hughes
  • Substituted 4'-hydroxyphenyl guanidines and methods of using the same
    Patent number: 4014934
    Abstract: Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: March 29, 1977
    Assignee: Armour Pharmaceutical Company
    Inventors: John Lawrence Hughes, Robert Chung-Huan Liu
  • Pharmaceutical preparations containing 5'-(8'-hydroxyquinolyl)guanidine compounds and methods of using same
    Patent number: 4000279
    Abstract: A pharmaceutical preparation consisting of a pharmaceutical grade carrier and a therapeutically active amount of an aromatic guanidine compound having the formula: ##STR1## or a non-toxic acid addition salt thereof are found to have biologically useful activity. These guanidine preparations and salts are shown to be active as vasoconstrictor agents and obtain useful biological results when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
    Type: Grant
    Filed: July 16, 1975
    Date of Patent: December 28, 1976
    Assignee: Armour Pharmaceutical Company
    Inventors: John Lawrence Hughes, Robert Chung-Huan Liu
  • Pharmaceutical guanidine preparations and methods of using same
    Patent number: 3976787
    Abstract: Pharmaceutical preparations and methods of using the same to treat a host having a condition requiring vasoconstrictive therapy. The preparations comprise a pharmaceutically acceptable carrier and a guanidine compound, or non-toxic acid addition salt thereof, having the structural notation: ##SPC1##Wherein: R.sub.1 is hydrogen or alkyl having 1-4 carbon atoms; R.sub.2 is hydrogen, hydroxy, chloro, fluoro or bromo; and R.sub.3 is hydrogen or the same as R.sub.2 when R.sub.2 is chloro, bromo or fluoro.
    Type: Grant
    Filed: March 6, 1975
    Date of Patent: August 24, 1976
    Assignee: Armour Pharmaceutical Company
    Inventors: John Lawrence Hughes, Robert Chung-Huan Liu, Takashi Enkoji, James Winslow Bastian
  • 5'-(8'-Hydroxyquinolyl)guanidine compounds
    Patent number: 3947455
    Abstract: A novel aromatic guanidine compound having the formula: ##SPC1##Is found to have biological activity. This guanidine compound and its salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: March 30, 1976
    Assignee: Armour Pharmaceutical Company
    Inventors: John Lawrence Hughes, Robert Chung-Huan Liu