Patents by Inventor Robert Coffman

Robert Coffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic composition against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
    Patent number: 12296002
    Abstract: The present invention relates to an immunogenic composition against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially to an immunogenic composition having a recombinant SARS-CoV-2 S protein and adjuvant.
    Type: Grant
    Filed: June 18, 2021
    Date of Patent: May 13, 2025
    Assignees: MEDIGEN VACCINE BIOLOGICS CORPORATION, DYNAVAX TECHNOLOGIES CORPORATION
    Inventors: Tsun-Yung Kuo, Charles Chen, Chung-Chin Wu, Yi-Jiun Lin, Meei-Yun Lin, Yu-Chi Wu, John Darren Campbell, Robert S. Janssen, David Novack, Robert Coffman, Paula Traquina
  • ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE TLR7/8 AGONIST COMPOUNDS AND USES THEREOF
    Publication number: 20240368155
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Application
    Filed: April 8, 2024
    Publication date: November 7, 2024
    Applicant: Dynavax Technologies Corporation
    Inventors: Stewart D. CHIPMAN, Radwan KIWAN, Melissa A. KACHURA, Robert COFFMAN
  • Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof
    Patent number: 11981670
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Grant
    Filed: August 16, 2021
    Date of Patent: May 14, 2024
    Assignee: Dynavax Technologies Corporation
    Inventors: Stewart D. Chipman, Radwan Kiwan, Melissa A. Kachura, Robert Coffman
  • ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE TLR7/8 AGONIST COMPOUNDS AND USES THEREOF
    Publication number: 20220033400
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Application
    Filed: August 16, 2021
    Publication date: February 3, 2022
    Applicant: Dynavax Technologies Corporation
    Inventors: Stewart D. CHIPMAN, Radwan KIWAN, Melissa A. KACHURA, Robert COFFMAN
  • Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof
    Patent number: 11124510
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: September 21, 2021
    Assignee: DYNAVAX TECHNOLOGIES CORPORATION
    Inventors: Stewart D. Chipman, Radwan Kiwan, Melissa A. Kachura, Robert Coffman
  • Methods and compositions for inhibition of innate immune responses and autoimmunity
    Publication number: 20070238678
    Abstract: The invention provides immunoregulatory polynucleotides and methods for immunoregulation of individuals using the immunoregulatory polynucleotides.
    Type: Application
    Filed: August 24, 2005
    Publication date: October 11, 2007
    Inventors: Franck Barrat, Robert Coffman
  • Methods and compositions for induction or promotion of immune tolerance
    Publication number: 20060193869
    Abstract: The invention provides non-immunostimulatory polynucleotide antigen conjugates and methods for treating unwanted immune reactions in individuals using the non-immunostimulatory polynucleotide antigen conjugates.
    Type: Application
    Filed: December 16, 2005
    Publication date: August 31, 2006
    Inventors: Franck Barrat, Robert Coffman
  • IL-4 and IL-10 to downregulate delayed-type hypersensitivity and cytokine expresion by T-cells
    Patent number: 5601815
    Abstract: The invention provides in vivo methods for potentiating IL-10 mediated inhibition of cytokine production by T cells in a mammal. The method comprises co-administering to the mammal an effective amount of IL-4 and IL-10, preferably intravascularly.
    Type: Grant
    Filed: September 21, 1995
    Date of Patent: February 11, 1997
    Inventors: Fiona Powrie, Robert Coffman
  • Pair of golf shoes
    Patent number: D427752
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: July 11, 2000
    Inventors: Robert Coffman, Glen Williams