Abstract: A method for treating a tumor, comprising identifying a tumor as a glioblastoma tumor and implanting in the tumor identified as a glioblastoma tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 6.5 Mega becquerel (MBq) hour and 14.3 MBq hour, per centimeter length.

Abstract: A method for treating a tumor, comprising identifying a tumor as a melanoma tumor and implanting in the tumor identified as a melanoma tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.2 Mega becquerel (MBq) hour and 7.5 MBq hour, per centimeter length.

Abstract: A method for treating a tumor, comprising identifying a tumor as a colorectal cancer tumor and implanting in the tumor identified as a colorectal cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 9.2 MBq hour, per centimeter length.

Abstract: A watercraft comprising a hull, a first attachment coupled to an exterior surface of the hull, a second attachment coupled to the exterior surface of the hull, and a closed-loop cooling system. The closed-loop cooling system includes a pump, a first channel at least partially formed by the first attachment, a second channel at least partially formed by the second attachment, the second channel in fluid communication with the first channel, and a coolant circulated through the first channel and the second channel by the pump.

Abstract: A vascular inhibitor for use as a medicament for treatment of a tumor of a patient wherein the administration pattern of the medicament comprises administering a therapeutically effective amount of the vascular inhibitor to the patient, in one or more sessions, and implanting seeds (204) carrying radium-224 in the tumor for intra-tumoral alpha-emitter radiotherapy less than two weeks from administering the vascular inhibitor.

Abstract: A method for treating a tumor, comprising identifying a tumor as a pancreatic cancer tumor and implanting in the tumor identified as a pancreatic cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 5.6 Mega becquerel (MBq) hour and 11.6 MBq hour, per centimeter length.

Abstract: A method for treating a cancerous tumor, by implanting in the cancerous tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon of at least 10 Mega becquerel (MBq) hour, per centimeter length. Optionally, the sources (21) are implanted in an array (160) of sources (21), each source separated from its neighboring sources (21) in the array by not more than 4.5 millimeters.

Abstract: A method for treating a tumor, comprising identifying a tumor as a breast cancer tumor and implanting in the tumor identified as a breast cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 9 MBq hour, per centimeter length.

Abstract: A watercraft comprising a hull, an electric drive, a battery electrically coupled to the electric drive, and an actuation assembly coupled to the battery. The battery is movable with respect to the hull by the actuation assembly between a first position and a second position.

Abstract: An integrated circuit for translating and reverse-translating the address included in a memory request is disclosed. The integrated circuit may first comprise a processor, a first boundary function, a second boundary function, and a component device. The processor is configured to transmit a memory request to a target module over a bus of the integrated circuit. The memory request requests access to one or more memory mapped resources and the memory request includes a physical address. The first boundary function is configured to translate the physical address to a relative address which operates in or applies to a different address space than an address space that the physical address operates in or applies to. The second boundary function is configured to translate the relative address to the physical address. The device is configured utilize the physical address transmitted by the second boundary function.

Abstract: A method for treating a tumor, comprising identifying a tumor as a squamous cell carcinoma tumor and implanting in the tumor identified as a squamous cell carcinoma tumor at least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 8.6 MBq hour, per centimeter length.

Abstract: A cable distribution system that includes a head end connected to a plurality of customer devices through a transmission network that includes a remote fiber node that converts digital data to analog data suitable for the plurality of customer devices, where the head end includes a processor. A packetized elementary stream of a video is provided from the head end to customer devices through the transmission network, wherein the packetized elementary stream includes a plurality of groups comprising pairs of packetized elementary stream headers and packetized elementary stream payloads. A first one of the plurality of groups corresponding to a non-predicted coded picture of the video of the packetized elementary stream is determined. The first one of the plurality of groups is encrypted while not encrypting all of the plurality of groups of the video.

Abstract: The present invention provides methods of determining a survival predictor score of a subject having mantle cell lymphoma (MCL). The present invention also provides methods of predicting the survival outcome of a subject having MCL and provides methods of selecting a treatment for a subject having MCL.

Abstract: The invention is directed to methods for selecting a treatment option for an activated B cell-like diffuse large B cell lymphoma (ABC DLBCL) subject, a germinal center B cell-like diffuse large B cell lymphoma (GCB DLBCL) subject, a primary mediastinal B cell lymphoma (PMBL) subject, a Burkitt lymphoma (BL) subject, or a mantle cell lymphoma (MCL) subject by analyzing digital gene expression data obtained from the subject, e.g., from a biopsy sample.

Abstract: The current invention discloses a transit seal plug, the seal plug to be releasably secured to a dispensing cap. The sealing member includes first and second annular sealing faces, and further also includes a gripping member which extends away from a first side of the sealing member to engage walls of a conduit. A pull tab extends from the opposite side of the sealing member, to facilitate removal of the seal plug from a dispensing cap.

Abstract: The current invention discloses a transit seal plug, the seal plug to be releasably secured to a dispensing cap. The sealing member includes first and second annular sealing faces, and further also includes a gripping member which extends away from a first side of the sealing member to engage walls of a conduit. A pull tab extends from the opposite side of the sealing member, to facilitate removal of the seal plug from a dispensing cap.

Abstract: A thermoforming system and related methods for manufacturing thermoplastic parts, such as interior panels for aircraft, may include a roll-to-roll operation and a forming press having at least one selectively rotatable tool. The rotatable tool, which may include a mold and/or a die, may be multifaceted, such that different faces of the tool have different mold arrangements for different forming characteristics.

Abstract: A cable distribution system that includes a head end connected to a plurality of customer devices through a transmission network that includes a remote fiber node that converts digital data to analog data suitable for the plurality of customer devices, where the head end includes a processor. A packetized elementary stream of a video is provided from the head end to customer devices through the transmission network, wherein the packetized elementary stream includes a plurality of groups comprising pairs of packetized elementary stream headers and packetized elementary stream payloads. A first one of the plurality of groups corresponding to a non-predicted coded picture of the video of the packetized elementary stream is determined. The first one of the plurality of groups is encrypted while not encrypting all of the plurality of groups of the video.

Abstract: A thermoforming system and related methods for manufacturing thermoplastic parts, such as interior panels for aircraft, may include a roll-to-roll operation and a forming press having at least one selectively rotatable tool. The rotatable tool, which may include a mold and/or a die, may be multifaceted, such that different faces of the tool have different mold arrangements for different forming characteristics.