Abstract: Provided are functional segregated telodendrimers having, for example, two or three functional segments. The telodendrimers can aggregate to form nanocarriers. The telodendrimers can have one or more tetracycline drugs (such as CMT-3) physically bound thereto that release under physiological conditions. Such nanocarriers with loaded CMT-3 disperse stably in aqueous solution and may be used in treating inflammatory disease through local or systemic administration. Also provided are methods of treating acute respiratory distress syndrome (ARDS) and/or CARDS in a subject in need thereof, including: administering a therapeutically effective amount of CMT-3 and one or more nonantimicrobial host-modulators directly to the lungs of the patient. In embodiments, CMT-3 is administered to the lungs in an aerosolized formulation. In embodiments, subsequent to CMT-3 administration, one or more non-antimicrobial host-modulators directly to the lungs of the patient.

Abstract: A pressure and/or temperature relief header for use in an HVAC heat transfer coil includes a main body adapted to be secured to bends in fluid coils of the HVAC fluid tube system. The main body includes holes in alignment with holes formed in the bends to enable liquid to pass from the bends into the expansion relief header. The expansion relief headers include a pressure release valve that automatically opens, preferably in response to pressure exceeding a predetermined threshold value or temperature falling below a predetermined value, to release liquid from the expansion relief header and then reseats. A discharge housing collects liquid released through the pressure release valve. A sensor detects the presence of liquid in the discharge housing.

Abstract: A pressure and/or temperature relief header for use in an HVAC heat transfer coil includes a main body adapted to he secured to bends in fluid coils of the HVAC fluid tube system, The main body includes holes in alignment with holes formed in the bends to enable liquid to pass from the bends into the expansion relief header. The expansion relief headers include a pressure release valve that automatically opens, preferably in response to pressure exceeding a predetermined threshold value or temperature falling -below a predetermined value, to release liquid from the expansion relief header and then reseats. A discharge housing collects liquid released through the pressure release valve. A sensor detects the presence of liquid in the discharge housing.

Abstract: An expansion relief header and its method of operation are disclosed for use in an HVAC heat transfer coil. The expansion relief header includes a main body adapted to be secured to bends in fluid coils of the HVAC fluid tube system. The main body includes holes in alignment with holes formed in the bends to enable fluid to pass from the bends into the expansion relief header. The expansion relief headers include one or more relief devices, such as valves, that automatically open, preferably in response to pressure exceeding a predetermined threshold value or temperature falling below a predetermined value, to release fluid from the expansion relief header and then reseat themselves.

Abstract: An expansion relief header is disclosed for use in an HVAC heat transfer coil. The expansion relief header includes a main body adapted to be secured to bends in fluid coils of the HVAC fluid tube system. The main body includes holes in alignment with holes formed in the bends to enable fluid to pass from the bends into the expansion relief header. The expansion relief headers include one or more relief devices, such as valves, that automatically open, preferably in response to pressure exceeding a predetermined threshold value or temperature falling below a predetermined value, to release fluid from the expansion relief header and then reseat themselves.

Abstract: An expansion relief header and its method of operation are disclosed for use in an HVAC heat transfer coil. The expansion relief header includes a main body adapted to be secured to bends in fluid coils of the HVAC fluid tube system. The main body includes holes in alignment with holes formed in the bends to enable fluid to pass from the bends into the expansion relief header. The expansion relief headers include one or more relief devices, such as valves, that automatically open, preferably in response to pressure exceeding a predetermined threshold value or temperature falling below a predetermined value, to release fluid from the expansion relief header and then reseat themselves.

Abstract: An expansion relief header is disclosed for use in an HVAC heat transfer coil. The expansion relief header includes a main body adapted to be secured to bends in fluid coils of the HVAC fluid tube system. The main body includes holes in alignment with holes formed in the bends to enable fluid to pass from the bends into the expansion relief header. The expansion relief headers include one or more relief devices, such as valves, that automatically open, preferably in response to pressure exceeding a predetermined threshold value or temperature falling below a predetermined value, to release fluid from the expansion relief header and then resent themselves.