Patents by Inventor Robert D. Gordon

Robert D. Gordon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160243091
    Abstract: An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a patient in need thereof, preferable a kidney or liver transplant patient. The dosage form releases the active substance over an extended period of time. It also provides improved pharmacokinetic parameters due to an extended and constant in vivo release including substantial decreased peak concentrations, despite increased bioavailability, substantial extended times for maximal concentration, and higher minimal concentrations when compared with conventional immediate release dosage forms and a recent modified release tacrolimus dosage form.
    Type: Application
    Filed: February 11, 2016
    Publication date: August 25, 2016
    Inventors: Robert D. GORDON, Per HOLM, Anne-Marie LADEMANN, Tomas NORLING
  • Publication number: 20140179731
    Abstract: An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a patient in need thereof, preferable a kidney or liver transplant patient. The dosage form releases the active substance over an extended period of time. It also provides improved pharmacokinetic parameters due to an extended and constant in vivo release including substantial decreased peak concentrations, despite increased bioavailability, substantial extended times for maximal concentration, and higher minimal concentrations when compared with conventional immediate release dosage forms and a recent modified release tacrolimus dosage form.
    Type: Application
    Filed: December 26, 2013
    Publication date: June 26, 2014
    Applicant: Veloxis Pharmaceuticals A/S
    Inventors: Robert D. Gordon, Per Holm, Anne-Marie Lademann, Tomas Norling
  • Patent number: 8685998
    Abstract: An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a patient in need thereof, preferable a kidney or liver transplant patient. The dosage form releases the active substance over an extended period of time. It also provides improved pharmacokinetic parameters due to an extended and constant in vivo release including substantial decreased peak concentrations, despite increased bioavailability, substantial extended times for maximal concentration, and higher minimal concentrations when compared with conventional immediate release dosage forms and a recent modified release tacrolimus dosage form.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: April 1, 2014
    Assignee: Veloxis Pharmaceuticals A/S
    Inventors: Robert D. Gordon, Per Holm, Anne-Marie Lademann, Tomas Norling
  • Patent number: 8664239
    Abstract: An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a patient in need thereof, preferable a kidney or liver transplant patient. The dosage form releases the active substance over an extended period of time. It also provides improved pharmacokinetic parameters due to an extended and constant in vivo release including substantial decreased peak concentrations, despite increased bioavailability, substantial extended times for maximal concentration, and higher minimal concentrations when compared with conventional immediate release dosage forms and a recent modified release tacrolimus dosage form.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: March 4, 2014
    Assignee: Veloxis Pharmaceuticals A/S
    Inventors: Robert D. Gordon, Per Holm, Anne-Marie Lademann, Tomas Norling
  • Patent number: 8135603
    Abstract: The method of applying constraints across a generally extensible and configurable resource delivery system as a basis for identifying or calculating the relative impacts of each constraint on resource delivery to various points and, through the use of constraint release mechanisms, developing prescriptive courses of action to optimize and increase the certainty of delivery of the resource, or in the reverse sense, restrict delivery of the resource. In an embodiment of the present invention, a method for characterizing the availability and potential use of water resources alongside associated impacts in order to identify and time the various policy decisions and investments needed to ensure access to water supplies over time given multiple stakeholders and uncertain, variable supplies and demands where such embodiment provides additional methods generally applicable across the full scope of embodiments of the invention.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: March 13, 2012
    Inventor: Robert D. Gordon
  • Publication number: 20120029009
    Abstract: An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a patient in need thereof, preferable a kidney or liver transplant patient. The dosage form releases the active substance over an extended period of time. It also provides improved pharmacokinetic parameters due to an extended and constant in vivo release including substantial decreased peak concentrations, despite increased bioavailability, substantial extended times for maximal concentration, and higher minimal concentrations when compared with conventional immediate release dosage forms and a recent modified release tacrolimus dosage form.
    Type: Application
    Filed: June 23, 2011
    Publication date: February 2, 2012
    Applicant: LifeCycle Pharma A/S
    Inventors: Robert D. Gordon, Per Holm, Anne-Marie Lademann, Tomas Norling
  • Publication number: 20110275659
    Abstract: An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a patient in need thereof, preferable a kidney or liver transplant patient. The dosage form releases the active substance over an extended period of time. It also provides improved pharmacokinetic parameters due to an extended and constant in vivo release including substantial decreased peak concentrations, despite increased bioavailability, substantial extended times for maximal concentration, and higher minimal concentrations when compared with conventional immediate release dosage forms and a recent modified release tacrolimus dosage form.
    Type: Application
    Filed: June 23, 2011
    Publication date: November 10, 2011
    Applicant: LifeCycle Pharma A/S
    Inventors: Robert D. GORDON, Per HOLM, Anne-Marie LADEMANN, Tomas NORLING
  • Publication number: 20100105717
    Abstract: An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a patient in need thereof, preferable a kidney or liver transplant patient. The dosage form releases the active substance over an extended period of time. It also provides improved pharmacokinetic parameters due to an extended and constant in vivo release including substantial decreased peak concentrations, despite increased bioavailability, substantial extended times for maximal concentration, and higher minimal concentrations when compared with conventional immediate release dosage forms and a recent modified release tacrolimus dosage form.
    Type: Application
    Filed: July 7, 2009
    Publication date: April 29, 2010
    Applicant: LifeCycle Pharma A/S
    Inventors: Robert D. Gordon, Per Holm, Anne-Marie Lademann, Tomas Norling
  • Patent number: 7179890
    Abstract: There is provided a novel vascular endothelial growth factor, herein designated VEGF-X, in addition to the nucleic acid molecule encoding it, a host cell transformed with said vector and compounds which inhibit or enhance angiogenesis. Also provided is the sequence of a CUB domain present in the sequence of VEGF-X which domain itself prevents angiogenesis and which is used to treat diseases associated with inappropriate vascularisation or angiogenesis.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: February 20, 2007
    Assignee: Janssen Pharmaceutica.N.V.
    Inventors: Robert D. Gordon, Jörg J. Sprengel, Jeffrey R. Yon, Josiena J. H. Dijkmans, Anna Gosiewska, Sridevi N. Dhanaraj, Jean Xu
  • Patent number: 6783953
    Abstract: There is provided a novel vascular endothelial growth factor, herein designated VEGF-X, in addition to the nucleic acid molecule encoding it, a host cell transformed with said vector and compounds which inhibit or enhance angiogenesis. Also provided is the sequence of a CUB domain present in the sequence of VEGF-X which domain itself prevents angiogenesis and which is used to treat diseases associated with inappropriate vascularisation or angiogenesis.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: August 31, 2004
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Robert D. Gordon, Jörg J. Sprengel, Jeffrey R. Yon, Josiena J. H. Dijkmans, Anna Gosiewska, Sridevi N. Dhanaraj, Jean Xu
  • Publication number: 20040115213
    Abstract: The invention relates to a method for treating a patient having a fungal infection. The invention comprises administering to the patient a therapeutically effective amount of a polyene antifungal (e.g., amphotericin B) in association with a therapeutically effective amount of a interleukin-2 inhibitor (e.g., chimeric or humanized monoclonal antibody that binds to the p55 subunit of the human interleukin-2 receptor and inhibits binding of interleukin-2 to an interleukin-2 receptor).
    Type: Application
    Filed: October 1, 2003
    Publication date: June 17, 2004
    Inventors: Stanley Willetts Chapman, John Dale Cleary, Robert D. Gordon
  • Patent number: 5491778
    Abstract: A system is provided for generating transition effects for use on a visual display. The system includes a binary table for describing a transition effect and a method for ordering the rows in the table to produce the transition. The table includes an arbitrary number of rows, each row representing a cell (group of picture elements) on the display. A numerical value, based on any function of cell location, is associated with each cell. The table is then sorted according to the numerical values. Each row in the sorted table drives a step in the transition effect. The cells described by the various rows are changed in sorted order to display the material from the image being transitioned-to. The sequence of processing of the rows causes the desired transition effect. By varying the function used to order the rows, an infinite variety of transition effects can be created.
    Type: Grant
    Filed: October 17, 1994
    Date of Patent: February 13, 1996
    Assignee: International Business Machines Corporation
    Inventors: Robert D. Gordon, Joseph F. Sinnott, Jr., Lonnie S. Walling
  • Patent number: 5414805
    Abstract: A computer system generates transition effects for use on a visual display. The system includes a binary table for describing a transition effect and a method for ordering the rows in the table to produce the transition. The table includes an arbitrary number of rows, each row representing a cell (group of picture elements) on the display. A numerical value, based on any function of cell location, is associated with each cell. The table is then sorted according to the numerical values. Each row in the sorted table drives a step in the transition effect. The cells described by the various rows are changed in sorted order to display the material from the image being transitioned-to. The sequence of processing of the rows causes the desired transition effect. By varying the function used to order the rows, an infinite variety of transition effects can be created.
    Type: Grant
    Filed: November 6, 1992
    Date of Patent: May 9, 1995
    Assignee: International Business Machines Corporation
    Inventors: Robert D. Gordon, Joseph F. Sinnott, Jr., Lonnie S. Walling
  • Patent number: 5390289
    Abstract: A method of generating a second, substantially anti-aliased, representation of a character from a first representation. The second representation is comprised of horizontal lines of dots that are shifted horizontally relative to dots of the first representation, each dot of the first representation having a value DOT1 associated therewith. The method include a step of, for each horizontal line (1-m) within the first representation of a character and for each dot (1-j) within a horizontal line, (a) determining a modifying value (DOT1k) associated with a dot(k) of the first representation, DOT1k being a function of DOT1 of the dot(k). The method includes another step of determining a value (DOT2k) of a corresponding dot for the second representation, the value of the corresponding dot being determined in accordance with the expression DOT2k=((DOT1-DOT1k )+DOT1(k-1)), where DOT1(k-1) is a modifying value of an adjacent dot on the horizontal line.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: February 14, 1995
    Assignee: International Business Machines Corporation
    Inventors: Bradley J. Beitel, Robert D. Gordon, Joseph B. Witherspoon, III
  • Patent number: 5274758
    Abstract: A user/PC interface system is described which enables the creation and performance of a synchronized audio/visual story on the PC. The interface enables the initial storage of a plurality of visual images. Then, it enables the creation of an audio presentation which includes labels and time indications, certain of which are employed for synchronization purposes. The system is responsive to a label to execute a predetermined command upon the appearance of the label in the audio presentation. The PC is then operated to perform the audio presentation, that performance automatically causing the display of visual images upon the occurrence of labels and time indications.An improved, table-based authoring system is also described for preparation of both the above noted audio and visual presentations. The system relies upon columnar presentations of a tabular form, each column indicating a separate control function (or comment) relating to the audio/visual presentation.
    Type: Grant
    Filed: December 28, 1992
    Date of Patent: December 28, 1993
    Assignee: International Business Machines
    Inventors: Bradley J. Beitel, Mark S. Bishop, Nancy A. Burns, John J. Deacon, Robert D. Gordon, Charles L. Haug, Kenneth B. Smith, Lonnie S. Walling, Michael D. Wilkes, Peter C. Yanker
  • Patent number: 5150312
    Abstract: Method and apparatus for generating relative movement between a first image and a second image while avoiding display screen flicker. The method includes a step of copying to a first buffer a portion of a display memory corresponding to a present portion of the second image wherein a first image will first appear. The method further includes the steps of superimposing within the display memory the first image upon the present portion of the second image and copying to a second buffer the portion of the display memory corresponding to the present portion of the second image, including the first image superimposed thereon, and a portion of the display memory corresponding to a next portion of the second image wherein the first image will next appear. The method further includes the steps of erasing the first image from the second buffer by copying the present portion from the first buffer to the second buffer and superimposing, within the second buffer, the first image upon the next portion of the second image.
    Type: Grant
    Filed: June 16, 1989
    Date of Patent: September 22, 1992
    Assignee: International Business Machines Corporation
    Inventors: Bradley J. Beitel, Robert D. Gordon
  • Patent number: 5119474
    Abstract: A user/PC interface system is described which enables the creation and performance of a synchronized audio/visual story on the PC. The interface enables the initial storage of a plurality of visual images. Then, it enables the creation of an audio presentation which includes labels and time indications, certain of which are employed for synchronization purposes. The system is responsive to a label to execute a predetermined command upon the appearance of the label in the audio presentation. The PC is then operated to perform the audio presentation, that performance automatically causing the display of visual images upon the occurrence of labels and time indications. A table-based authoring system is also described for preparation of both the above noted audio and visual presentations. The system relies upon columnar presentations of a tabular form, each column indicating a separate control function (or comment) relating to the audio/visual presentation.
    Type: Grant
    Filed: July 11, 1991
    Date of Patent: June 2, 1992
    Assignee: International Business Machines Corp.
    Inventors: Bradley J. Beitel, Mark S. Bishop, John J. Deacon, Robert D. Gordon, Kenneth B. Smith, Lonnie S. Walling, Michael D. Wilkes, Peter C. Yanker, Nancy A. Burns, Charles L. Haug
  • Patent number: 4937760
    Abstract: A method for synchronizing common values in a distributed system, at least one node of which is a cyclic, rule-based, object-sensitive production system. Values altered in one part of the system are implicity rather than explicitly communicated and processed to and from the rule-based node. All communications to the rule-based node of common values changed by the nonrule-based nodes are by way of a list independent of and concurrently with any procedural request of the rule-based node, there being no necessary relation between the list contents and the procedural request.
    Type: Grant
    Filed: September 19, 1988
    Date of Patent: June 26, 1990
    Assignee: International Business Machines Corporation
    Inventors: Bradley J. Beitel, Robert D. Gordon, Ming C. Hao, Steven V. Kauffman, Ronald L. Obermarck, Arthur M. Sherman, Lynne C. Thieme, Gene E. Trivett, Lynn Trivett