Patents by Inventor Robert D. MacKenzie

Robert D. MacKenzie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ethylenediamine derivatives useful in treating sickle cell anemia
    Patent number: 4060630
    Abstract: Compounds of the following general formula are useful in the treatment of sickle cell anemia: ##STR1## WHEREIN EACH OF R and R.sub.1 is hydrogen, chlorine, fluorine, bromine, trifluoromethyl, hydroxy, a lower alkoxy group of from 1 to 4 carbon atoms or a straight or branched lower alkyl group of from 1 to 4 carbon atoms; R.sub.2 is hydrogen or a straight or branched lower alkyl group of from 1 to 4 carbon atoms; R.sub.3 is hydrogen or a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or when R.sub.2 is hydrogen, R.sub.3 is .beta.,.beta.,.beta.-trichloroethoxycarbonyl, benzyloxycarbonyl, p-methoxybenzyloxycarbonyl, p-nitrobenzyloxycarbonyl or tert-butoxycarbonyl; or NR.sub.2 R.sub.3 taken together form a monocyclic heterocyclic group selected from the group consisting of pyrrolidino, piperidino, morpholino, and N-(lower)alkylpiperazino; Z is ##STR2## wherein R.sub.4 is hydrogen or lower alkyl of from 1 to 4 carbon atoms, and R.sub.
    Type: Grant
    Filed: December 22, 1975
    Date of Patent: November 29, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Joseph E. Dolfini, Robert D. MacKenzie
  • .alpha.-Alkylbenzyl lactamimides
    Patent number: 4055561
    Abstract: Novel derivatives of .alpha.-alkylbenzyl lactamimide are useful as anticoagulants.
    Type: Grant
    Filed: April 25, 1973
    Date of Patent: October 25, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: J. Martin Grisar, George P. Claxton, Robert D. MacKenzie