Patents by Inventor Robert D. MacPhee

Robert D. MacPhee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6682648
    Abstract: An immunochemical and molecular biologic endpoint reporter system in which reaction products, coupled to electrochemically active molecules susceptible to redox recycling or coupled to enzymes capable of proportional generation of said electrochemically active molecules, are detected and/or quantitated using amperiometry in conjunction with a silicon microchip possessing a closely spaced interdigitated array of nobel metal electrodes.
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: January 27, 2004
    Assignee: University of Southern California
    Inventors: Robert D. MacPhee, Clive R. Taylor, Rainer Hintsche, Rene Seitz
  • Patent number: 6562209
    Abstract: An electronic controller, such as a programmed microcontroller (33), controls a series of pumps (P1-P6) to automatically sequence the pumping of the individual fluids required by the ELISA procedure into a cell (or cells) necessary to produce a reporter, control the positioning of the carrier of the reporter (32, 35) adjacent the reporter sensor (28), analyze the data obtained from the reporter sensor and display (36) the concentration of the bioagent determined from the analysis of the foregoing data. The foregoing elements automate the ELISA procedure. Once started, the apparatus, governed by the program, conducts the test automatically without the necessity for human intervention. In accordance with a specific aspect, the foregoing components may be housed in a single package for easy portability; may be battery powered or line powered.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: May 13, 2003
    Assignee: Northrop Grumman Corporation
    Inventors: Brian M. Sullivan, Denes L. Zsolnay, Robert D. MacPhee, Jr., Richard K. McHugh
  • Publication number: 20020166764
    Abstract: A device and reporter system wherein an electrochemical assay is performed on attractable beads which are attracted onto an electrochemical sensor for measurement of the electrochemically active molecules generated by the assay in proportion to the presence and quantity of the analyte.
    Type: Application
    Filed: April 9, 2002
    Publication date: November 14, 2002
    Applicant: University of Southern California
    Inventor: Robert D. MacPhee