Abstract: An immunochemical and molecular biologic endpoint reporter system in which reaction products, coupled to electrochemically active molecules susceptible to redox recycling or coupled to enzymes capable of proportional generation of said electrochemically active molecules, are detected and/or quantitated using amperiometry in conjunction with a silicon microchip possessing a closely spaced interdigitated array of nobel metal electrodes.

Abstract: An electronic controller, such as a programmed microcontroller (33), controls a series of pumps (P1-P6) to automatically sequence the pumping of the individual fluids required by the ELISA procedure into a cell (or cells) necessary to produce a reporter, control the positioning of the carrier of the reporter (32, 35) adjacent the reporter sensor (28), analyze the data obtained from the reporter sensor and display (36) the concentration of the bioagent determined from the analysis of the foregoing data. The foregoing elements automate the ELISA procedure. Once started, the apparatus, governed by the program, conducts the test automatically without the necessity for human intervention. In accordance with a specific aspect, the foregoing components may be housed in a single package for easy portability; may be battery powered or line powered.

Abstract: A device and reporter system wherein an electrochemical assay is performed on attractable beads which are attracted onto an electrochemical sensor for measurement of the electrochemically active molecules generated by the assay in proportion to the presence and quantity of the analyte.