Patents by Inventor Robert Daines

Robert Daines has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL POLYMORPHS OF REBAUDIOSIDE C AND METHODS FOR MAKING AND USING THE SAME
    Publication number: 20150064117
    Abstract: Embodiments of this invention encompass a method for producing and purifying rebaudioside C. In particular, this invention relates to a method for purifying rebaudioside C compositions to obtain a substantially pure rebaudioside C product using one or more crystallization steps. Resulting polymorphic forms of rebaudioside C, substantially pure rebaudioside C compositions and their uses are disclosed.
    Type: Application
    Filed: October 31, 2014
    Publication date: March 5, 2015
    Applicant: Redpoint Bio Corporation
    Inventors: F. Raymond Salemme, Robert A. Daines
  • Novel Polymorphs of Rebaudioside C and Methods for Making and Using the Same
    Publication number: 20120230922
    Abstract: Embodiments of this invention encompass a method for producing and purifying rebaudioside C. In particular, this invention relates to a method for purifying rebaudioside C compositions to obtain a substantially pure rebaudioside C product using one or more crystallization steps. Resulting polymorphic forms of rebaudioside C, substantially pure rebaudioside C compositions and their uses are disclosed.
    Type: Application
    Filed: September 22, 2010
    Publication date: September 13, 2012
    Applicant: Redpoint Bio Corporation
    Inventors: F. Raymond Salemme, Robert A. Daines
  • Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
    Patent number: 8071592
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: December 6, 2011
    Assignee: Glaxo Group Limited
    Inventors: Lluis Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J Remuiñan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • Hydrazone Compounds and Their Use
    Publication number: 20110033393
    Abstract: The present invention relates to hydrazone compounds of Formula I: and pharmaceutically acceptable salts and stereoisomers thereof, wherein R1, R2, R3, R4, L1, and L2 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I as inhibitors of TRPM5 protein.
    Type: Application
    Filed: May 12, 2010
    Publication date: February 10, 2011
    Inventors: Philip STEIN, Robert DAINES, Dennis SPROUS, Harold O'GRADY
  • Antimicrobial Compounds
    Publication number: 20100081650
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: November 17, 2009
    Publication date: April 1, 2010
    Inventors: Jeffrey Michael Axten, Robert A. Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • Antibacterial compounds
    Patent number: 7622481
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: November 24, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey Michael Axten, Robert A Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES
    Publication number: 20090270374
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: July 18, 2007
    Publication date: October 29, 2009
    Inventors: Llius Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A. Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J. Remuinan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B. Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • Compounds
    Patent number: 7498326
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man. The piperidine derivatives include compounds of formula (I): wherein RA, AB, n, R3, R2 and R4 are defined herein. For example, RA is an optionally substituted bicyclic carbocyclic or heterocyclic ring system, and R4 is a group U-R5 in which R5 is an optionally substituted bicyclic heterocyclic ring system as defined herein (e.g. optionally substituted pyrido [3,2, -b][1,4] thiazin-yl).
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: March 3, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey Michael Axten, Robert A Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • Aminopiperidine derivatives
    Patent number: 7312212
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: December 25, 2007
    Assignee: Glaxo Group Limited
    Inventors: Robert A Daines, William Henry Miller, Neil David Pearson, Israil Pendrak, Mark Andrew Seefeld
  • Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
    Patent number: 7109213
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: September 19, 2006
    Assignee: Glaxo Group Limited
    Inventors: Robert A Daines, William Henry Miller, Neil David Pearson, Israil Pendrak, Mark Andrew Seefeld
  • Compounds
    Publication number: 20060189604
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: June 25, 2003
    Publication date: August 24, 2006
    Inventors: Jeffrey Axten, Robert Daines, David Davies, Timothy Gallagher, Graham Jones, William Miller, Neil Pearson, Israil Pendrak
  • Compounds
    Publication number: 20060058287
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: June 25, 2003
    Publication date: March 16, 2006
    Inventors: Jeffrey Axten, Robert Daines, David Davies, Timothy Gallagher, Graham Jones, William Miller, Neil Pearson, Israil Pendrak
  • Aminopiperidine derivatives
    Publication number: 20050159411
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: January 27, 2003
    Publication date: July 21, 2005
    Inventors: Robert Daines, William Miller, Neil Pearson, Israil Pendrak, Mark Seefeld
  • Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
    Publication number: 20050085494
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: January 27, 2003
    Publication date: April 21, 2005
    Inventors: Robert Daines, William Miller, Neil Pearson, Israil Pendrak, Mark Seefeld
  • Fatty acid synthase inhibitors
    Patent number: 6670388
    Abstract: This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: December 30, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Robert A. Daines, Siegfired B. Christensen, IV, Jack D. Leber, Martha S. Head
  • Fatty acid synthase inhibitors
    Publication number: 20030220392
    Abstract: This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.
    Type: Application
    Filed: November 25, 2002
    Publication date: November 27, 2003
    Inventors: Jack Dale Leber, Siegfried Benjamin Christensen, Robert A Daines, Mei Li, Joseph Weinstock, Martha S Head
  • Fatty acid synthase inhibitors
    Patent number: 6608059
    Abstract: This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: August 19, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Robert A. Daines, Israil Pendrak
  • Fatty acid synthase inhibitors
    Patent number: 6498187
    Abstract: This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.
    Type: Grant
    Filed: February 19, 2002
    Date of Patent: December 24, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Siegfried B. Christensen, IV, Robert A. Daines, Jack D. Leber, Israil Pendrak, Joseph Weinstock
  • Indole compounds
    Patent number: 6486211
    Abstract: Novel indole derivatives, pharmaceutical compositions containing these compounds and their use as inhibitors of the fatty acid synthase FabH are disclosed.
    Type: Grant
    Filed: April 2, 2002
    Date of Patent: November 26, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Robert A. Daines, William Dennis Kingsbury, Israil Pendrak
  • Indole compounds useful for treating bacterial infections
    Patent number: 6486192
    Abstract: This invention relates to the use of certain indole compounds, which are active as inhibitors of the fatty acid synthase FabH, for the treatment of bacterial infections.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: November 26, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Robert A. Daines, Pamela A. Chambers