Patents by Inventor Robert Dodd
Robert Dodd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12258333Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.Type: GrantFiled: October 20, 2023Date of Patent: March 25, 2025Assignee: VERTEX PHARMACEUTICALS INCORPORATEDInventors: Elizabeth Mary Beck, Steven John Durrant, Sarah Skerratt, Robert Pullin, Gorka Etxebarria Jardi, David Matthew Shaw, Nadia M. Ahmad, Christopher Wray, Anisa Nizarali Virani, Kiri North, James Dodd, Michael Edward O'Donnell, Bhairavi Galan, Ronald Marcellus Knegtel, Ewa Iwona Chudyk, Joanne Louise Pinder, Stephen Andrew Thomson, Lidio Marx Carvalho Meireles, Dean Stamos, Yvonne Schmidt, Joseph Pontillo, Sara S. Hadida Ruah, Timothy Donald Neubert, Dennis James Hurley, Jinglan Zhou
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Patent number: 11285133Abstract: The present application relates to novel 3-imidazolines of formula (I?) and (I) below: (I?) (I) Wherein Ar1, Ar2, Ar3, and R1 to R6 are as defined in the claims. The 3-imidazolines of the invention are useful in antibiotic therapies, in particular as inhibitors of carbapenemases. They are also useful as antibiotics themselves. The present invention also concerns a method for preparing more specifically the 3-imidazolines of formula (I). The present invention further relates to conjugates of said compounds with known antibiotics.Type: GrantFiled: March 8, 2018Date of Patent: March 29, 2022Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ PARIS-SUD, ASSISTANCE PUBLIQUE—HOPITAUX DE PARISInventors: Kevin Cariou, Robert Dodd, Eugénie Romero, Mohamed Benchekroun, Bogdan Iorga, Thierry Naas, Saoussen Oueslati
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Patent number: 11174226Abstract: The present application relates to novel azetidinimine of formula (I). Wherein R1-R6 are as defined in claim 1. The azetidinimine of the invention are useful as antibiotics and as inhibitors of a carbapenemases. The present invention thus further relates to their use in antibiotic therapies and their methods of synthesis.Type: GrantFiled: September 7, 2016Date of Patent: November 16, 2021Assignee: Centre National de la Recherche Scientifique (CNRS)Inventors: Robert Dodd, Kevin Cariou, Corinne Minard, Bogdan-Iuliu Iorga, Thierry Naas
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Publication number: 20210128530Abstract: The present application relates to novel 3-imidazolines of formula (I?) and (I) below: (I?) (I) Wherein Ar1, Ar2, Ar3, and R1 to R6 are as defined in the claims. The 3-imidazolines of the invention are useful in antibiotic therapies, in particular as inhibitors of carbapenemases. They are also useful as antibiotics themselves. The present invention also concerns a method for preparing more specifically the 3-imidazolines of formula (I). The present invention further relates to conjugates of said compounds with known antibiotics.Type: ApplicationFiled: March 8, 2018Publication date: May 6, 2021Inventors: Kevin CARIOU, Robert DODD, Eugénie ROMERO, Mohamed BENCHEKROUN, Bogdan IORGA, Thierry NAAS, Saoussen OUESLATI
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Publication number: 20190055194Abstract: The present application relates to novel azetidinimine of formula (I). Wherein R1-R6 are as defined in claim 1. The azetidinimine of the invention are useful as antibiotics and as inhibitors of a carbapenemases. The present invention thus further relates to their use in antibiotic therapies and their methods of synthesis.Type: ApplicationFiled: September 7, 2016Publication date: February 21, 2019Inventors: Robert Dodd, Kevin Cariou, Corinne Minard, Bogdan-Iuliu Iorga, Thierry Naas
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Patent number: 9078874Abstract: Compounds having inverse agonist functional selectivity for GABAA receptors containing the ?5 subunit for use as a medicament in the treatment of cognitive impairments in subjects suffering from Down syndrome. The use of these compounds is disclosed. Pharmaceutical compositions for such treatment can comprise these compounds or suitable pharmaceutically acceptable salt thereof, a polyethoxylated castor oil and dimethyl sulfoxide (DMSO). Methods are disclosed for enhancing cognitive function, or treating or lessening the severity of cognitive impairments, in subjects suffering from Down syndrome by administering to a subject in need thereof a pharmaceutically effective amount of one or more of these compounds.Type: GrantFiled: August 24, 2010Date of Patent: July 14, 2015Assignee: Centre National De La Recherche Scientifique—CNRSInventors: Marie-Caude Potier, Robert Dodd, Benoît Delatour, Jérôme Braudeau, Yann Herault
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Patent number: 8516765Abstract: A building panel has a unitary foamed core, and a unitary cover layer of resinous polymeric material covering the core and covering a bottom edge or drip edge and an upper edge of the panel. A system for installation of adjacent panels includes the adjacent panels having vertical clip-receiving grooves slidably receiving narrow edges of a clip. The clip holds adjacent panels in coplanar abutting relationship to minimize movement while installed on a wall of a building.Type: GrantFiled: November 5, 2008Date of Patent: August 27, 2013Assignee: Certainteed CorporationInventors: Robert Shaw, David Beck, David Stucky, David Steele, Robert Dodd, Jamie Valentine
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Publication number: 20120283248Abstract: Compounds having inverse agonist functional selectivity for GABAA receptors containing the ?5 subunit for use as a medicament in the treatment of cognitive impairments in subjects suffering from Down syndrome. The use of these compounds is disclosed. Pharmaceutical compositions for such treatment can comprise these compounds or suitable pharmaceutically acceptable salt thereof, a polyethoxylated castor oil and dimethyl sulfoxide (DMSO). Methods are disclosed for enhancing cognitive function, or treating or lessening the severity of cognitive impairments, in subjects suffering from Down syndrome by administering to a subject in need thereof a pharmaceutically effective amount of one or more of these compounds.Type: ApplicationFiled: August 24, 2010Publication date: November 8, 2012Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRSInventors: Marie-Claude Potier, Robert Dodd, Benoît Delatour, Jérôme Braudeau, Yann Herault
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Publication number: 20100281801Abstract: A building panel has a unitary foamed core, and a unitary cover layer of resinous polymeric material covering the core and covering a bottom edge or drip edge and an upper edge of the panel. A system for installation of adjacent panels includes the adjacent panels having vertical clip-receiving grooves slidably receiving narrow edges of a clip. The clip holds adjacent panels in coplanar abutting relationship to minimize movement while installed on a wall of a building.Type: ApplicationFiled: November 5, 2008Publication date: November 11, 2010Applicant: Certain Teed CorporationInventors: Robert Shaw, David Beck, David Stucky, David Steele, Robert Dodd, Jamie Valentine
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Patent number: 7350493Abstract: A distributor is described for a multi-cylinder laser ignited internal combustion engine. The distributor includes a shaft rotatable by the engine and a plurality of flat reflective surfaces on the shaft. The surfaces lie in planes normal to the axis of rotation of the shaft and are axially staggered from one another along the length of the shaft. An optical transmitter directs light from a laser source to impinge at an angle sequentially on the reflective surfaces as the shaft rotates, and a plurality of optical receivers spaced from one another each receive the light reflected from a respective one of the mirror surfaces and direct the reflected light to a respective one of the engine cylinders.Type: GrantFiled: June 29, 2006Date of Patent: April 1, 2008Assignee: Ford Global Technologies, LLCInventors: Andy Scarisbrick, Stephan Carroll, Robert Dodd, Tom Shenton, Geoff Dearden, Steve Keen, Roy Clissold, John McCulloch
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Patent number: 7199524Abstract: A magnetron output arrangement includes a coaxial output adapted to be coupled in an endfire configuration to a rectangular waveguide. The waveguide has a flange for mating with the magnetron output arrangement. The coaxial output includes a central conductor. The output arrangement further includes a plate located in a predetermined position with respect to the central conductor. The plane of the plate is arranged to be substantially perpendicular to the axis of the coaxial output. The plate is located a predetermined distance from the end of the central conductor, such that the coaxial output in use couples with the plate so that the output coupling is substantially the same regardless of the type of waveguide flange employed.Type: GrantFiled: March 17, 2003Date of Patent: April 3, 2007Assignee: E2V Technologies (UK) LimitedInventors: Michael Barry Clive Brady, Geoffrey Robert Dodd, Martin Bernard Edwards, Bernard Richard Mulcahy
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Publication number: 20070000465Abstract: A distributor is described for a multi-cylinder laser ignited internal combustion engine. The distributor includes a shaft rotatable by the engine and a plurality of flat reflective surfaces on the shaft. The surfaces lie in planes normal to the axis of rotation of the shaft and are axially staggered from one another along the length of the shaft. An optical transmitter directs light from a laser source to impinge at an angle sequentially on the reflective surfaces as the shaft rotates, and a plurality of optical receivers spaced from one another each receive the light reflected from a respective one of the mirror surfaces and direct the reflected light to a respective one of the engine cylinders.Type: ApplicationFiled: June 29, 2006Publication date: January 4, 2007Inventors: Andy Scarisbrick, Steph Carroll, Robert Dodd, Tom Shenton, Geoff Dearden, Steve Keen, Roy Clissold, John McCulloch
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Patent number: 7084167Abstract: The invention concerns compounds of general formula (I) wherein: the group X represents a —NR4, —CH?N or —CHR5-NR4-group; the group Y represents an oxygen or sulphur atom or a NR, —CR5, —CHR5-, —CR5=CR6- or —CHR5-CHR6 group provided that when group X represents the —CH?N— or —CHR5-NR4-group, group Y represents an oxygen or a sulphur atom or a Nr, —CR5 or —CHR group; the group R represents a hydrogen atom or an alkyl, aryl or aralkyl group; the groups R1, R5 and R6, identical or different, represent each a hydrogen or halogen atom or an alkyl or alkoxy group; the group R2 represents a hydrogen atom or an alkyl group; the group R3 represents an aryl group; and the group R4 represents a hydrogen atom, an alkyl, aryl, aralkyl, alkylsulphonamide, arylsulphonamide or aralkylsulphonamide group; and their salt with a pharmaceutically acceptable acid, in the form of a racemic mixture and their optically pure isomer.Type: GrantFiled: May 23, 2001Date of Patent: August 1, 2006Assignee: Centre National de la Rechereche Scientifique (CNRS)Inventors: Martial Ruat, Robert Dodd, Hélène Véronique Faure, Philippe Marcel Dauban, Albane Kessler, Pierre Jean-Paul Potier
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Publication number: 20060029775Abstract: A process and apparatus for making a shingle, together with the shingle made thereby, is provided, in which one or more thermoplastic materials are extruded or co-extruded to form an extrudate, with the extrudate being cut into a preliminary shingle shape, which is allowed to dissipate heat, and then is delivered to a compression mold, wherein the preliminary shingle shape is compression molded to substantially its final dimensions and is then discharged from the mold and allowed to cool.Type: ApplicationFiled: September 15, 2005Publication date: February 9, 2006Inventors: Thomas Kevin MacKinnon, Robert Dodd, Joong Kim, Douglas Wylie
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Publication number: 20050192317Abstract: The invention concerns diamines of general formula (I), wherein: A represents a group A1 or A2 of general formula (II); B represents a group B1 or B2 of general formula (III); X represents a SO2, CH2, C?O or COO; YZ represents a group of formula CH(R25)—CH(R26) or CH(R27)?(R28), and R1 to R28, identical or different, represent independently of one another, a hydrogen or halogen atom or an alkyl, cycloalkyl, CN, NO2, hydroxy, aryl, aralkyl, alkoxy, aryloxy, amino, alkylamino, dialkylamino, cycloalkylamino, arylamino, arylalkylamino, diarylamino diarylalkylamino, trihalogenoalkyl or trihalogenoalkoxy group, provided that in the group A1, at least one of the radicals R1, R2, R3, R4 or R5 represents the hydrogen atom when the other four do not represent the hydrogen atom and in the group B1, at least one of the radicals R13, R14, R15, R16 or R17 represents the hydrogen atom when the other four do not represent the hydrogen atom, and their salts with a pharmaceutically acceptable acid, in the form of racemic mixtuType: ApplicationFiled: August 7, 2001Publication date: September 1, 2005Inventors: Philippe Dauban, Robert Dodd, Helene Faure, Martial Ruat, Pierre Potier, Albane Kessler
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Patent number: 6660769Abstract: The invention concerns compounds represented by general formula (I) wherein: Z represents a sulfur or oxygen atom; the groups R1 and R2, identical or different, represent each a alkyl group or an alkenyl group; X represents a CO, a CO2, an SO, or an SO2 and the group R represents an alkyl, aryl, alkenyl, or aralkyl group, provided that when Z represents an oxygen atom, X an SO2 and R a group (a), R1 and R2 do not both represent the methyl group. The invention also concerns methods for preparing said compounds, pharmaceutical compositions containing them and their use as promoter of &ggr;-aminobutyric acid and as medicine particularly designed for treating nervous disorders.Type: GrantFiled: June 26, 2002Date of Patent: December 9, 2003Assignees: Centre National de la Recherche Scientifique (CNRS), Innovationsagentur GmbH, Universite de BernInventors: Robert Dodd, Ahmed El Hadri, Jean-Paul Pierre Potier, Werner Sieghart, Frantisek Jursky, Roman Furtmuller, Erwin Sigel, Urs Thomet
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Patent number: 6649626Abstract: The invention concerns compounds of general formula (I) wherein: Z represents a sulphur or oxygen atom, NH, N-alkyl or Nboc; group R′, identical or different, represent each a hydrogen atom, a OCH3 group or a OCH2O group; group R″ represents a hydrogen or a CH3 group; group X represents a carbonyl, sulphonyl or CO2 group; and group R represents an alkyl, aryl, alkenyl or aralkyl group. The invention also concerns the preparation of said compounds, pharmaceutical compositions containing them and their use for stimulating &ggr;-amino-butyric acid activity and as medicine for treating nervous disorders.Type: GrantFiled: August 15, 2002Date of Patent: November 18, 2003Assignees: Centre National de la Recherche Scientifique (CNRS), Universite de Bern, Innovationsagentur GmbHInventors: Robert Dodd, Rodolphe Razet, Pierre Jean-Paul Potier, Werner Sieghart, Frantisek Jursky, Roman Furtmuller, Erwin Sigel, Urs Thomet
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Publication number: 20030199497Abstract: The invention concerns compounds of general formula (I) wherein: 1Type: ApplicationFiled: April 24, 2003Publication date: October 23, 2003Inventors: Martial Ruat, Robert Dodd, Helene Veronique Faure, Philippe Marcel Dauban, Albane Kessler, Pierre Jean-Paul Potier
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Patent number: D616735Type: GrantFiled: February 19, 2009Date of Patent: June 1, 2010Assignee: CertainTeed CorporationInventors: Robert Shaw, David Beck, David Stucky, David Steele, Robert Dodd, James (Jamie) Valentine
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Patent number: D663047Type: GrantFiled: February 19, 2009Date of Patent: July 3, 2012Assignee: Certainteed CorporationInventors: Robert Shaw, David Beck, David Stucky, David Steele, Robert Dodd, James (Jamie) Valentine