Abstract: A 2-aryl-pyridylazole compound and derivatives useful in slowing the growth of cancer cells are disclosed. Also disclosed are methods of synthesizing the compound, methods of using pharmaceutical compositions containing the compound as an ingredient to slow the growth of cancer cells, and methods of treating cancer patients with pharmaceutical compositions containing the compound as an ingredient.

Abstract: A 2-aryl-pyridylazole compound and derivatives useful in slowing the growth of cancer cells are disclosed. Also disclosed are methods of synthesizing the compound, methods of using pharmaceutical compositions containing the compound as an ingredient to slow the growth of cancer cells, and methods of treating cancer patients with pharmaceutical compositions containing the compound as an ingredient.

Abstract: Compositions and methods for treating multiple sclerosis are disclosed herein. Embodiments of the present invention include methods of treating a multiple sclerosis patient via the administration of a therapeutically effective amount of a composition comprising a compound of the formula: wherein, R1 is heteroalkyl, heterocycloalkyl, or heteroaryl; R2, R4 and R6 are independently hydrogen, halogen, nitro, amino, hydroxy, C1-C6 alkyl, C1-C6 heteroalkyl, heterocycloalkyl or aryl; R3, R5, and R7 are independently hydrogen or C1-C6 alkyl, or R3 and R4 taken together with the carbon atoms to which they are attached form a phenyl ring, or R4 and R5 taken together with the carbon atoms to which they are attached form a phenyl ring, or R5 and R7 taken together with the carbon atoms to which they are attached form a phenyl ring; and n1 and n2 are independently 0, 1 or 2; or a pharmaceutically acceptable salt, a prodrug, or a mixture thereof.

Abstract: A method is disclosed herein for displaying time lapse for an on-line auction for an item in a computer. According to the method, the processor time in the computer is obtained and compared to the official auction time for the items being auctioned in the on-line auction which is obtained from the on-line auction service. The users computer compares the obtained processor time to the obtained official auction time and correlates the end of time from the on-line auction service to a processor end of time which corresponds to the user's time. The computer then displays the time left correlated to the processor's time preferably in a visual countdown graphical icon.

Abstract: The present invention provides compositions useful in treating cancer. The compositions include a synergistic combination of an antineoplastic thiol-binding mitochondrial oxidant with an antineoplastic nucleic acid binding agent, an antineoplastic antimetabolite base analog, or docetaxel. Also provided are methods of assaying the synergistic effects of the combinations and methods of treating cancer using the synergistic combinations.

Abstract: A method of stimulating the production of melanin by the pigment-producing cells (keratinocytes and/or melanocytes) of the skin, in particular for the induction of skin tanning in humans, comprises administering alpha-MSH or an alpha-MSH analogue and exposing the skin to ultraviolet irradiation.

Abstract: A pharmaceutically active composition comprising a pharmaceutically acceptable carrier and one or more alpha-MSH or analogues thereof for use in the stimulation of integumental melanocytes in vertebrates in order to bring about the production of melanin is disclosed.

Abstract: A method for stimulating integumental melanocytes by the topical application of alpha-MSH analogs, and compositions comprising said analogs for use in the method are described.

Abstract: A method for stimulating integumental melanocytes by the topical application of alpha-MSH analogs, and compositions comprising said analogs for use in the method are described.