Abstract: A detergent product containing a detergent composition is provided.

Abstract: Pouches, for example pouches that contain one or more active agents, such as a fabric care active agent or dishwashing active agent and/or detergent compositions, and more particularly pouches employing a water-soluble fibrous wall material, pouches employing a fibrous wall material that ruptures during use, and methods for making same, are provided.

Abstract: Some embodiments relate to imageable radioisotopic microspheres. In some embodiments, the imageable microspheres are radiolabeled with imageable radioisotopes. In some embodiments, the imageable radioisotope is directly coupled to a surface of a substrate of the microsphere. In some embodiments, the imageable microspheres can be used as surrogate particles to predict the distribution of therapeutic microspheres comprising radiotherapeutic isotopes.

Abstract: Some embodiments relate to imageable radioisotopic microspheres. In some embodiments, the imageable microspheres are radiolabeled with imageable radioisotopes. In some embodiments, the imageable radioisotope is directly coupled to a surface of a substrate of the microsphere. In some embodiments, the imageable microspheres can be used as surrogate particles to predict the distribution of therapeutic microspheres comprising radiotherapeutic isotopes.

Abstract: The invention provides for a medical instrument (200) comprising a magnetic resonance imaging system (202) and a high-intensity focused ultrasound system (204) with an electronically controllable and a mechanically controllable focus.

Abstract: Some embodiments relate to imageable radioisotopic microspheres. In some embodiments, the imageable microspheres are radiolabeled with imageable radioisotopes. In some embodiments, the imageable radioisotope is directly coupled to a surface of a substrate of the microsphere. In some embodiments, the imageable microspheres can be used as surrogate particles to predict the distribution of therapeutic microspheres comprising radiotherapeutic isotopes.

Abstract: A therapeutic apparatus (900, 1000) comprising a high intensity focused ultrasound system (904) for heating a target zone (940, 1022). The therapeutic apparatus further comprises a magnetic resonance imaging system (902). The therapeutic apparatus further comprises a memory (952) containing machine executable instructions (980, 982, 984, 986, 988, 990) for execution by a processor (944). Execution of the instructions cause the processor to: generate (702, 802) heating commands (964) which cause the high intensity focused ultrasound system to sonicate the subject; repeatedly acquire (704, 804) magnetic resonance data (954) during execution of the heating commands; repeatedly calculate (706, 806) a spatially dependent parameter (970); and repeatedly modify (708, 808) the heating commands in accordance with the spatially dependent parameter such that within the target zone the spatially dependent parameter remains below a first predetermined threshold and above a second predetermined threshold.

Abstract: Extension for a cylinder of a vibration damper comprising a base and a tube portion adjoining the latter. The base and the tube portion are formed in one piece. The tube portion has a circumferential bend pleat with respect to the base.

Abstract: Extension for a cylinder of a vibration damper comprising a base and a tube portion adjoining the latter. The base and the tube portion are formed in one piece. The tube portion has a circumferential bend pleat with respect to the base.

Abstract: A mild hyperthermia treatment apparatus (10) includes an imager (12), which generates a planning image (34) and temperature maps (36) of a target region. An array of ultrasonic transducer drivers (52) individually drives ultrasonic transducers of a phased array of ultrasonic transducers (50). One or more processors or units receive a target temperature profile, and calculate power, frequency, and relative phase for the transducer drivers to drive the phased array of ultrasonic transducers to generate a multi-foci sonication pattern configured to heat the target region with the target temperature profile while limiting peak acoustic pressures. During treatment, the imager generates a series of temperature maps which the one or more processors or units compare with the target temperature profile and, based on the comparison, adjust the power, frequency and relative phase with which the transducer drivers drive the ultrasonic transducers.

Abstract: The invention provides for a medical instrument (200) comprising a magnetic resonance imaging system (202) and a high-intensity focused ultrasound system (204) with an electronically controllable and a mechanically controllable focus.

Abstract: A therapeutic apparatus (900, 1000) comprising a high intensity focused ultrasound system (904) for heating a target zone (940, 1022). The therapeutic apparatus further comprises a magnetic resonance imaging system (902). The therapeutic apparatus further comprises a memory (952) containing machine executable instructions (980, 982, 984, 986, 988, 990) for execution by a processor (944). Execution of the instructions cause the processor to: generate (702, 802) heating commands (964) which cause the high intensity focused ultrasound system to sonicate the subject; repeatedly acquire (704, 804) magnetic resonance data (954) during execution of the heating commands; repeatedly calculate (706, 806) a spatially dependent parameter (970); and repeatedly modify (708, 808) the heating commands in accordance with the spatially dependent parameter such that within the target zone the spatially dependent parameter remains below a first predetermined threshold and above a second predetermined threshold.

Abstract: The pole plunger includes a main shaft having an upper disc secured to an upper end and a lower disc secured to a lower end. The lower disc has a radius greater than that of the upper disc, allowing the user to select the appropriately sized disc which matches the radius of a drain pipe to be plunged. Additionally, a handle portion may be secured to the main shaft, extending in a direction orthogonal thereto, providing the user with a handle to grip during the plunging process. The handle portion further has a handle disc secured to its free end, with the handle disc having a radius between that of the upper and lower discs, providing the user with a third size disc for plunging of the drain pipe.

Abstract: The present invention provides conjugate compounds comprising (a) an active compound; (b) optionally, but in some embodiments preferably, an affinity binding agent; and (c) a block copolymer, the block copolymer comprising: (i) a first elastin-like polypeptide having a first Tt and (U) a second elastin-like polypeptide having a second Tt greater than the first Tt. Method for the targeted delivering of an active compound in vivo to a selected region within a subject with such agents are also described.

Abstract: The pole plunger includes a main shaft having an upper disc secured to an upper end and a lower disc secured to a lower end. The lower disc has a radius greater than that of the upper disc, allowing the user to select the appropriately sized disc which matches the radius of a drain pipe to be plunged. Additionally, a handle portion may be secured to the main shaft, extending in a direction orthogonal thereto, providing the user with a handle to grip during the plunging process. The handle portion further has a handle disc secured to its free end, with the handle disc having a radius between that of the upper and lower discs, providing the user with a third size disc for plunging of the drain pipe.

Abstract: A system and method for selectively treating a ventricular tachycardia based on sensed atrial and ventricular intervals from the patient's heart. A detection window of the ten most recent atrial and ventricular intervals are analyzed for the occurrence of either tachycardia or fibrillation. When a majority of the sensed intervals are satisfied, the apparatus starts a duration time interval. Ventricular intervals and atrial intervals are compare, ventricular interval greater than the atrial interval by a bias factor the system delivers tachycardia therapy to the heart. Alternatively, the method withholds tachycardia therapy to the heart when the atrial rate is classified as atrial fibrillation and the ventricular response is unstable.

Abstract: A method and apparatus for generating a multiphasic defibrillation/cardioversion waveform as well as a multiphasic fibrillation inducing pulse train. The multiphasic fibrillation inducing waveform being applied to the same electrodes as the defibrillation/cardioversion waveform.

Abstract: A method and apparatus for automatically adjusting the sensing threshold in an automatic implantable cardioverter/defibrillator with pacing capability. Fixed sensitivity is used for a specified interval following each pacing pulse and automatic sensitivity adjustment is used when spontaneous cardiac depolarization is detected. For spontaneous cardiac depolarization, the sensing threshold is automatically adjusted to a value proportional to the amplitude of the sensed cardiac signal. The sensing threshold continuously decreases between sensed cardiac depolarizations, ensuring that a lower level cardiac signal will be detected. When a pacing pulse is delivered, the sensing threshold is set to a fixed value and held at that value for a predetermined period of time such that the sensing threshold will not be affected by the cardiac response evoked by the pacing pulse. At the end of the predetermined period of time, the sensing threshold is decreased as it would following a spontaneous cardiac depolarization.