Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

Abstract: A system and method are disclosed that track a deliverable to a user. The system includes an identifier or tag secured to the deliverable, a computer system for interrogating the identifier, and a personal device in communication with the computer system, wherein the personal device is held by the user at the time the user is administered the deliverable to detect the unique identity associated with the identifier device and confirms delivery of the deliverable to the user. The method includes attaching an identifiable tag that produces a unique signature to the deliverable, interrogating the tag at about the time of delivery to the user, and confirming that the user has been administered the deliverable through detecting the identifiable tag.

Abstract: The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also measure the conditions of the environment surrounding the system.

Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

Abstract: Ingestible event markers comprising an identifier and an ingestible component are provided. The ingestible component may vary, where ingestible components of interest include osmotic ingestible components, liquid capsules, tablets, multi-layered ingestible component and multi-compartment ingestible components. In some instances, the identifier is mechanically stably associated with the ingestible component. Also provided are systems that include the ingestible event markers, as well as methods of using the ingestible event markers.

Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

Abstract: High-throughput ingestible event marker manufacturing systems are provided. The systems include an assembly unit configured to stably associate an ingestible event marker with a carrier to produce a product. Also provided are manufacturing methods to produce such products which include assembling an ingestible event marker with an assembly unit configured to stably associate an ingestible event marker with a carrier.

Abstract: Pharmaceutical delivery systems for delivering dosages according to the present invention include a carrier component and a cap configured to seal an internal volume of the carrier component, wherein the cap includes a device that produces a unique current signature. Dosages prepared to be delivered according to embodiments of the invention find use in a variety of different applications, including clinical trials.

Abstract: Ingestible event markers having high reliability are provided. Aspects of the ingestible event markers include a support, a control circuit, a first electrochemical material, a second electrochemical material and a membrane. In addition, the ingestible event markers may include one or more components that impart high reliability to the ingestible event marker. Further, the ingestible event markers may include an active agent. In some aspects, the active agent, such as a pharmaceutically active agent or a diagnostic agent may be associated with the membrane.

Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

Abstract: A method of compensating for or correcting satellite ephemeris error involves measuring time difference of arrival (TDOA) and frequency difference of arrival (FDOA) for signal replicas received via two satellites (34, 46) from calibration transmitters (42a to 42d) at different geographical locations. An initial satellite ephemeris consisting of position and velocity vectors is used to calculate ephemeris changes yielding estimated TDOA and FDOA values providing a best fit to measured TDOA and FDOA values. This provides estimated changes required to compensate for or to correct errors in the initial satellite ephemeris. The method may be iterated to deal with large ephemeris changes: i.e. the changes obtained in one iteration may be used to correct ephemeris for use as a new initial ephemeris in a following iteration. The method may be used to correct ephemeris errors in one or both satellites, if so a greater number of calibration transmitters EphemCal 1 to EphemCal 10 may be used.

Abstract: In one embodiment the present invention includes a biometric information recognizer and a shape memory material. The biometric information recognizer recognizes biometric information (such as speech) and signals the shape memory material with a current. The current causes the shape memory material to change shape, thereby reconfiguring a mechanical device. Such mechanical device may include a lock. In such manner, the lock may be isolated from external tampering (such as physical stressing) yet receptive to biometric information for controlling access.

Abstract: A dynamic application data monitoring architecture may include data collector, data provider, and widget software components. Data collectors convert application data from a native format into data instances having a logical hierarchical structure conforming to a schema which may be an XML schema. Data providers receive data instances from associated data collectors or other data providers and generate other data instances having a different logical hierarchical structure conforming to another schema which may be presentation-centric and may define features of a graphical data display mechanism (e.g. a line graph). The data provider may employ an external transform (e.g. an XSLT). Widgets receive logical, presentation-centric data instances from an associated data source (typically a data provider) and generate therefrom a displayable graphical representation of the received data according to an operative graphical data display mechanism. The data instances may be Document Object Model document instances.