Abstract: Compositions that include Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFAs) are disclosed, along with methods of production and use thereof.

Abstract: Nitrone-based compositions are disclosed that may be utilized for the prevention and treatment of a variety of ophthalmic diseases or conditions where RPE65 protein isomerohydrolase is implicated. Methods of production and use of said nitrone-based compositions, as well as pharmaceutical and ophthalmic compositions containing same, are disclosed.

Abstract: The present invention relates to processes for production of Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFAs). The present invention also relates to compositions (e.g., nutritional supplements, food products, and pharmaceutic compositions) containing such VLC-PUFAs. In one embodiment, the present invention is directed to methods for biosynthesis and production of the VLC-PUFAs described herein (particularly C28-C40 PUFAs, also referred to herein as supraenes or supraenoics) by the expression, in a production host cell, of the full or partial sequence(s) of Elovl4 DNA/mRNA nucleic acids or ELOVL4 protein sequences encoded thereby, from any species (prokaryotic or eukaryotic) for use in the biosynthesis, production, purification and utilization of VLC-PUFAs in particular by the elongation of C18-C26 saturated fatty acids and PUFAs.

Abstract: The present invention relates to processes for production of Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFAs). The present invention also relates to compositions (e.g., nutritional supplements and food products) containing such VLC-PUFAs. In one embodiment, the present invention is directed to methods for biosynthesis and production of the VLC-PUFAs described herein (particularly C28-C38 PUFAs, also referred to herein as supraenes or supraenoics) by the expression, in a production host cell, of the full or partial sequence(s) of Elovl4 DNA/mRNA nucleic acids or ELOVL4 protein sequences encoded thereby, from any species (prokaryotic or eukaryotic) for use in the biosynthesis, production, purification and utilization of VLC-PUFAs in particular by the elongation of C18-C26 saturated fatty acids and PUFAs.

Abstract: The present invention relates to processes for production of Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFAs). The present invention also relates to compositions (e.g., nutritional supplements and food products) containing such VLC-PUFAs. In one embodiment, the present invention is directed to methods for biosynthesis and production of the VLC-PUFAs described herein (particularly C28-C38 PUFAs, also referred to herein as supraenes or supraenoics) by the expression, in a production host cell, of the full or partial sequence(s) of Elovl4 DNA/mRNA nucleic acids or ELOVL4 protein sequences encoded thereby, from any species (prokaryotic or eukaryotic) for use in the biosynthesis, production, purification and utilization of VLC-PUFAs in particular by the elongation of C18-C26 saturated fatty acids and PUFAs.

Abstract: A bed frame includes a base frame, an articulated support decks, an intermediate frame positioned between the base frame and the articulated support deck, and an auto-contour mechanism. The articulated support deck includes head, seat and foot deck portions. When engaged, the auto-contour mechanism adjusts the elevation of the seat deck portion and the foot deck portion in response to an adjustment of the head deck portion. The auto-contour mechanism is easily engaged/disengaged by manipulating a control lever. The bed frame can include siderails which are provided with a latching mechanism. The bed frame can also include a caster assembly that allows casters to be pivoted in an engaged position in which the bed frame rests on the casters, and a disengaged position in which the bed frame rests on legs.

Abstract: A bed frame includes a base frame, an articulated support decks, an intermediate frame positioned between the base frame and the articulated support deck, and an auto-contour mechanism. The articulated support deck includes head, seat and foot deck portions. When engaged, the auto-contour mechanism adjusts the elevation of the seat deck portion and the foot deck portion in response to an adjustment of the head deck portion. The auto-contour mechanism is easily engaged/disengaged by manipulating a control lever. The bed frame can include siderails which are provided with a latching mechanism. The bed frame can also include a caster assembly that allows casters to be pivoted in an engaged position in which the bed frame rests on the casters, and a disengaged position in which the bed frame rests on legs.

Abstract: A bed is provided including a frame, an accessory mount coupled to the frame, a siderail, and an ambulatory assist arm assembly. The accessory mount is configured to removably couple the siderail to the frame so that the siderail can be removed and replaced with the ambulatory assist arm assembly.

Abstract: A bed is provided including a frame, an accessory mount coupled to the frame, a siderail, and an ambulatory assist arm assembly. The accessory mount is configured to removably couple the siderail to the frame so that the siderail can be removed and replaced with the ambulatory assist arm assembly.

Abstract: An ambulatory assist apparatus is configured to be mounted to a frame of a bed. The ambulatory assist apparatus includes an ambulatory assist arm having a first end portion and a second end portion configured to provide a handle, a mounting plate configured to be coupled to the frame of the bed, and a pivot pin for pivotably coupling the ambulatory assist arm to the mounting plate. The mounting plate includes a plurality of spaced-apart apertures. The apparatus also includes a locking pin coupled to the first end portion of the assist arm. The locking pin is configured to engage a selected one of the plurality of apertures in the mounting plate to secure the ambulatory assist arm at different orientations relative to the mounting plate. The apparatus further includes an actuator to release the locking pin from the selected aperture to permit pivotable movement of the ambulatory assist arm relative to the mounting plate.

Abstract: An acoustic liner jet engine inlet barrel is formed from a perforated permeable skin, a honeycomb core, and a solid facesheet, each of which is formed in a one-piece configuration such that at most only a narrow single fore-to-aft splice, or no splice at all, is present in the finished product. The acoustic modal content remains unaffected, thus preserving a high degree of liner effectiveness, increasing the total active acoustic area of the barrel while decreasing its weight, and increasing its durability.

Abstract: In one embodiment a plasma ignitor (10) having a first dielectric housing (18), that encases a first portion of a first conductive lead (14) and a first portion of a second conductive lead (16), and end cap (30), that locks its filament (31) into position, is used to initiate a plasma within an etch chamber (64). The plasma is used to etch an integrated circuit substrate (62) and to form an etched surface (78). A conductive layer of material (80) is then deposited on the etched surface (78). The first dielectric housing (18) keeps the first portion of the first conductive lead (14) and the first portion of the second conductive lead (16) from shorting to one another during processing, and the end cap (30) prevents the filament (31) from falling off during processing. Thus, the present invention allows contact resistance to be repeatably minimized.

Abstract: An isocyanate composition is made by using a 2-component catalyst system--one which initiates at room temperature and one which initiates at a temperature of at least 75.degree. C. and has a one-hour half-life temperature of at least 90.degree. C.; the composition has a room temperature stability of at least thirty days.

Abstract: A thermosetting unsaturated polyester-polyurethane hybrid foam resin composition is made without significant blistering by using a 2-component catalyst system--one which initiates at room temperature and one which initiates at a temperature of at least 75.degree. C. and has a one-hour half-life temperature of at least 90.degree. C.; the composition has a room temperature stability of at least thirty days.

Abstract: A cabinet is provided with a curved, upwardly-swinging door and interior shelves. The curved shelf door is mounted on a pair of opposed pivot arms which rotate on a horizontal axis. Each pivot arm is provided with a disk portion having a central boss and an arm portion tangent to the disk portion. The central boss engages a fixed stud at the side of the cabinet and provides a center pivot for each of the arms. A gas spring for each arm is provided, which is pivotably connected at one end to the arm and at the other end to a side wall of the cabinet. The gas spring serves a dual purpose of counterbalancing the door as it moves between an open and a closed position and opening the door unassisted once the user initiates movement of the door, this opening feature being very beneficial to seated and physically disabled users.

Abstract: There is disclosed a lubricating composition consisting essentially of a lubricant base and a lubricant additive wherein the lubricant additive comprises at least two groups of ingredients, wherein, the first group is a triglyceride vegetable oil, a wax ester of a triglyceride vegetable oil and combinations, the second group is a sulfurized mixture of a triglyceride vegetable oil and a wax ester of a triglyceride vegetable oil, and the third group is a phosphite adduct of triglyceride vegetable oil, a phosphite adduct of wax ester and combinations.

Abstract: A cabinet is provided with a curved, upwardly-swinging door and interior shelves. The curved shelf door is mounted on a pair of opposed arms which rotate on a horizontal axis. Each arm is provided with two opposed, circularly arcuate slots and a central ellipsoidal slot, each slot engaging a fixed stud at the side of the cabinet. The ellipsoidal slot and its corresponding stud provide a center pivot for each of the arms. The arms are mounted inside the cabinet on opposed interior side walls. Lighting can be provided in a formed recess in the bottom of the cabinet. The cabinet can also be provided with plural internal shelves supported on planar brackets. The cabinet further can be provided with a pair of side-by-side doors and a center wall. Arms are mounted on each side of the center wall and adjacent the interior side walls of the cabinet, for separately mounting the doors.

Abstract: An improved method for producing high temperature superconductors comprising sintering ceramic superconductor material in a sealed confinement chamber made of non-reactive impervious material, thereby preventing loss of oxygen from the material during heating and eliminating the need for reoxygenation after sintering.

Abstract: A technique is provided for removing foam mandrel material from a stiffener section of a composite structural member as is employed in lightweight aircraft skin structures. The technique involves the direct pressure glass bead blasting of the mandrel material. By mounting a blasting nozzle within a rubber hose of larger diameter, an airstream containing glass beads may be directed outwardly through the nozzle while evacuating pressure is created in an annular passageway between the hose and the nozzle to evacuate mandrel foam particles as well as spent glass beads. The result is a clean channel within the stiffener section.

Abstract: The invention relates to an expansion fastener device that secures two interlocking members together. The device includes a parallelepiped receptacle having slits along opposite ends. The receptacle is inserted through the interlocking members and triple wedges are driven into the receptacle. The triple wedges includes a first wedge having tapers in the vertical direction and its insertion into receptacle causes only vertical expansion of the receptacle. A pair of horizontally tapered wedges are inserted into the receptacle alongside the first wedge and they cause only horizontal expansion of the receptacle. Utilization of the invention reduces stress points as created by conventional rivets.