Patents by Inventor Robert E. Braun
Robert E. Braun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250367256Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: ApplicationFiled: January 31, 2025Publication date: December 4, 2025Applicant: The Jackson LaboratoryInventors: Robert E. Braun, Manju Sharma
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Patent number: 12357674Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: GrantFiled: December 5, 2023Date of Patent: July 15, 2025Assignee: The Jackson LaboratoryInventors: Robert E. Braun, Manju Sharma
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Publication number: 20250170214Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: ApplicationFiled: January 31, 2025Publication date: May 29, 2025Applicant: The Jackson LaboratoryInventors: Robert E. Braun, Manju Sharma
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Publication number: 20240181008Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: ApplicationFiled: December 5, 2023Publication date: June 6, 2024Applicant: The Jackson LaborartoryInventors: Robert E. Braun, Manju Sharma
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Patent number: 11890322Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: GrantFiled: July 13, 2021Date of Patent: February 6, 2024Assignee: The Jackson LaboratoryInventors: Robert E. Braun, Manju Sharma
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Publication number: 20220062381Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: ApplicationFiled: July 13, 2021Publication date: March 3, 2022Applicant: The Jackson LaboratoryInventors: Robert E. Braun, Manju Sharma
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Publication number: 20200147174Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: ApplicationFiled: June 25, 2019Publication date: May 14, 2020Inventors: Robert E. BRAUN, Manju SHARMA
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Publication number: 20190307846Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: ApplicationFiled: June 25, 2019Publication date: October 10, 2019Inventors: Robert E. BRAUN, Manju SHARMA
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Patent number: 10376562Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: GrantFiled: March 14, 2014Date of Patent: August 13, 2019Assignee: The Jackson LaboratoryInventors: Robert E. Braun, Manju Sharma
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Publication number: 20160022773Abstract: The present invention generally relates to uses of glial cell line-derived growth factor (GDNF) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of GDNF, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein. The invention relates also to formulations and kits for achieving the indicated pharmaceutical advantages.Type: ApplicationFiled: March 14, 2014Publication date: January 28, 2016Inventors: Robert E. BRAUN, Manju SHARMA
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Patent number: 5031025Abstract: An individual integrated circuit package utilizing an intermediate die carrier having legs in contact with a wiring substrate and a compatible lid to effect hermeticity. More specifically, the carrier includes on its outer surface a raised section and a peripheral ledge. The cap is formed with a cutout in its closed extremity to accommodate the raised carrier section and the portions of the cap adjacent the cutout rest upon and are sealed to the carrier ledge. The rim of the cap at its open extremity contacts and is sealed to the substrate to form the completed hermetic package.Type: GrantFiled: February 20, 1990Date of Patent: July 9, 1991Assignee: Unisys CorporationInventors: Robert E. Braun, Ronald T. Gibbs
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Patent number: 4987478Abstract: An hermetic integrated circuit package having a single die wherein wire connections to area pads on the active face of the die are carried through an hermetic boundary comprised of a cover plate to an external interface with the next succeeding interconnect level. The package is comprised of a heat exchange element to which the die is attached, a cover plate having holes homologously positioned with respect to the area pads on the die and a seal ring for joining the heat exchange element to the cover plate. The wire connections which are carried through the holes and sealed to the cover plate are externally accessible.Type: GrantFiled: February 20, 1990Date of Patent: January 22, 1991Assignee: Unisys CorporationInventors: Robert E. Braun, Ronald T. Gibbs
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Patent number: 4510446Abstract: The present disclosure describes test coupons having predetermined respective test patterns, formed in a multilayer printed circuit board simultaneously with the fabrication of the latter. The test coupons are probed with conventional electrical instruments to provide information as to the occurrence of a misregistration of any given subsurface printed plane or trace, whether or not the misregistration exceeds a specified limit, and if desired, a measure of the degree of misregistration. The foregoing are readily accomplished in a time and cost efficient manner without the need for cross-sectioning portions of the board and the visual observation of the subsurface printed layers.Type: GrantFiled: November 3, 1982Date of Patent: April 9, 1985Assignee: Burroughs CorporationInventors: Robert E. Braun, John E. Benasutti
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Patent number: 4338621Abstract: The present disclosure describes an hermetically sealed integrated circuit package capable of accommodating high density circuit configurations with their attendant high power levels. In performing this function, the package permits the back-bonded integrated circuit chip or die to be mounted to a thermally conductive member of the package which is disposed in an open air stream. Moreover, the opposite side of the package positioned in proximity to the interconnection medium remains available to be fully populated by a large number of closely spaced input/output pins.Type: GrantFiled: February 4, 1980Date of Patent: July 6, 1982Assignee: Burroughs CorporationInventor: Robert E. Braun
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Patent number: 3955867Abstract: A connector or receptacle is described for connecting a leadless integrated circuit package to an interconnection medium such as a printed circuit board without the need for soldering connections. A significant feature of the connector is that all of its electrical contacts may be engaged or probed individually or collectively from the package side of the interconnection board for diagnostic and test purposes. Probe means suitable for use with the connector are also described.Type: GrantFiled: October 9, 1974Date of Patent: May 11, 1976Assignee: Burroughs CorporationInventors: Robert E. Braun, George J. Sprenkle
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Patent number: 3946276Abstract: A system is described which provides for high density packaging of electronic equipment, particularly data processing systems. Subnanosecond integrated circuits of the LSI or MSI type in pluggable packages are adapted to be installed in receptacles or connectors. A cooling frame is provided which supports the package connectors as well as the package-to-package interconnection medium. In accordance with the system, groups of integrated circuit packages logically partitioned into functional elements and having, for example, gate complexities of the order of four thousand to ten thousand gates, comprise an island. The system may be expanded further by interconnecting several islands.Type: GrantFiled: October 9, 1974Date of Patent: March 23, 1976Assignee: Burroughs CorporationInventors: Robert E. Braun, Richard H. Jones, George J. Sprenkle, Herbert Stopper
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Patent number: 3942854Abstract: A hold down device is described for applying a high clamping force to a "leadless" integrated circuit package installed in a suitable connector. Use of the device results in reliable electrical connections between the package circuit leads and the connector contact elements; and reliable thermal connections between the package carrier and a cooling frame provided to dissipate the heat generated by the integrated circuits. The hold down device has added system utility in the clamping of an interconnect cable assembly adapted to plug into the aforementioned connector in lieu of the integrated circuit package.Type: GrantFiled: October 9, 1974Date of Patent: March 9, 1976Assignee: Burroughs CorporationInventors: Peter P. Klein, Robert E. Braun