Patents by Inventor Robert E. Carlson
Robert E. Carlson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150093291Abstract: A sensitive, precise detector system for physiological analytes uses a novel system. The system comprises an immobilized polyol on a surface. Reversibly coupled to the polyol or analyte is a dendrimer structure. In the system, a signal is triggered by the dendrimer structure when in a competitive environment with an analyte at the surface. In one embodiment, the system is an implantable sensor for use by diabetic patients. The sensing system can produce a consistent, measurable response while functioning under biologically relevant conditions. The sensing system requires the interaction of two components: 1) a competitive agent/signaling component, a dendrimer-boronic acid construct (DBA) and 2) a binding environment for a glucose-competitive DBA competition, which is an immobilized monosaccharide mimic (iDIOL).Type: ApplicationFiled: August 13, 2012Publication date: April 2, 2015Applicant: RECEPTORS LLCInventors: Christina Thomas, Robert E. Carlson
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Publication number: 20120263771Abstract: The fiber structures in the form of a fiber (or fiber mass), woven or nonwoven fabric, fiber absorbent layers, mats or bats or other collection of fiber can be modified to be microbiocidal, bacteriostatic, obtain immobilized, microbes, etc. The disclosed fiber has the unique ability to capture and hold microbes or microbial generating units within the fiber mass.Type: ApplicationFiled: March 23, 2012Publication date: October 18, 2012Applicant: RECEPTORS LLCInventors: Robert E. Carlson, Kurt E. Heikkila, Karen Schlichtmann Schmidt, Robert M. Carlson
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Publication number: 20120241391Abstract: Disclosed are filter media constituents, filter media, filter constructions, and methods of employing the filter media and filter constructions for fluid filtration. The filter media and filter media constituents of the invention have unique properties enabling the efficient capture of microbes or microbial generating units. Fluids usefully filtered using the filter media and filter constructions include air and water.Type: ApplicationFiled: March 23, 2012Publication date: September 27, 2012Applicant: RECEPTORS LLCInventors: Robert E. Carlson, Karen Schlichtmann Schmidt, Robert M. Carlson
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Patent number: 7985715Abstract: The present invention relates to artificial receptors, arrays or microarrays of artificial receptors or candidate artificial receptors, methods of and compositions for making them, and methods of using them. Each artificial receptor includes a building block molecule that is a peptide of Formula: R1R2N—R3—(R4)n—X—(R5)m—Y—C(O)—R6, Tether-R1NH—Z-Ala-Gly-Ala-Gly-X-Ala-Y—C(O)—R6, R1R2NH—Z-Ala-Gly-Ala-Gly-X-Ala-Y—C(O)-Tether, Linker-R1NH—Z-Ala-Gly-Ala-Gly-X-Ala-Y—C(O)—R6, or R1R2NH—Z-Ala-Gly-Ala-Gly-X-Ala-Y—C(O)-Linker.Type: GrantFiled: September 9, 2005Date of Patent: July 26, 2011Assignee: Receptors LLCInventor: Robert E. Carlson
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Patent number: 7964535Abstract: The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building block compounds, typically immobilized in a spot on a support. The present invention also includes the building blocks, combinations of building blocks, arrays of building blocks, and receptors constructed of these building blocks together with a support. The present invention also includes methods of making and using these arrays and receptors.Type: GrantFiled: November 7, 2003Date of Patent: June 21, 2011Assignee: Receptors LLCInventor: Robert E. Carlson
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Patent number: 7960311Abstract: The present invention relates to methods employing artificial receptors, such as combinatorial artificial receptor arrays. The present receptors include heterogeneous and immobilized combinations of building block molecules. In certain embodiments, combinations of 2, 3, 4, or 5 distinct building block molecules immobilized near one another on a support provide molecular structures that can be employed in the present methods. The present methods can develop artificial receptors that can then be employed to detect the receptor's ligand. The present methods can find compounds that disrupt one or more binding interactions.Type: GrantFiled: September 3, 2004Date of Patent: June 14, 2011Assignee: Receptors LLCInventor: Robert E. Carlson
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Patent number: 7884052Abstract: The present invention relates to artificial receptors on scaffolds, methods of and compositions for making them, and methods of using them. Each artificial receptor includes a plurality of building block compounds coupled to a scaffold. In an embodiment, at least one of the building blocks includes a tether moiety. The tether can provide spacing or distance between the recognition element and the scaffold to which the building block is immobilized. A tether moiety can have any of a variety of characteristics or properties including flexibility, rigidity or stiffness, ability to bond to another tether moiety, and the like.Type: GrantFiled: September 1, 2005Date of Patent: February 8, 2011Assignee: Receptors LLCInventor: Robert E. Carlson
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Publication number: 20100133102Abstract: The present invention relates to sensors and sensor systems that utilize combinational artificial receptors. Embodiments of the present invention employ combinational artificial receptors in electromagnetic (e.g. optical) and electrochemical sensors.Type: ApplicationFiled: October 30, 2008Publication date: June 3, 2010Applicant: RECEPTORS, LLCInventor: Robert E. Carlson
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Publication number: 20090221439Abstract: The present invention relates to artificial receptors, arrays or microarrays of artificial receptors or candidate artificial receptors, methods of and compositions for making them, and methods of using them. Each artificial receptor includes a plurality of building block compounds. In an embodiment, at least one of the building blocks includes a tether moiety. The tether can provide spacing or distance between the recognition element and the support or scaffold to which the building block is immobilized. A tether moiety can have any of a variety of characteristics or properties including flexibility, rigidity or stiffness, ability to bond to another tether moiety, and the like.Type: ApplicationFiled: March 12, 2009Publication date: September 3, 2009Applicant: RECEPTORS LLCInventor: Robert E. Carlson
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Publication number: 20090203980Abstract: The present invention relates to sensors including artificial receptors and methods of using them. In an embodiment, the present invention includes an artificial receptor as a component of a receptor system including a ligand permeable interface that isolates the artificial receptor from certain components of the surrounding environment. In an embodiment, the present invention includes an artificial receptor and a competitor against a ligand of interest. In an embodiment, the present invention includes a competitive artificial receptor as a component of a detector system including a semipermeable membrane that isolates the competitive artificial receptor from certain components of the surrounding environment. This embodiment also includes the competitor and a detector operatively coupled to the competitive artificial receptor. The detector produces a signal indicating binding of the competitor and/or the ligand of interest to the artificial receptor.Type: ApplicationFiled: December 1, 2008Publication date: August 13, 2009Inventors: Robert E. Carlson, Rachel L. Weller Roska, Stephen A. Brose
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Patent number: 7504365Abstract: The present invention relates to artificial receptors, arrays or microarrays of artificial receptors or candidate artificial receptors, methods of and compositions for making them, and methods of using them. Each artificial receptor includes a plurality of building block compounds. In an embodiment, at least one of the building blocks includes a tether moiety. The tether can provide spacing or distance between the recognition element and the support or scaffold to which the building block is immobilized. A tether moiety can have any of a variety of characteristics or properties including flexibility, rigidity or stiffness, ability to bond to another tether moiety, and the like.Type: GrantFiled: September 1, 2005Date of Patent: March 17, 2009Assignee: Receptors LLCInventor: Robert E. Carlson
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Patent number: 7504364Abstract: The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building block compounds, typically immobilized in a spot on a support. The present invention also includes the building blocks, combinations of building blocks, arrays of building blocks, and receptors constructed of these building blocks together with a support. The present invention also includes methods of making and using these arrays and receptors.Type: GrantFiled: September 16, 2002Date of Patent: March 17, 2009Assignee: Receptors LLCInventor: Robert E Carlson
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Patent number: 7469076Abstract: The present invention relates to a sensor system that can include a waveguide, a detection system that is operatively coupled to the waveguide, and a working artificial receptor. The waveguide can be operatively configured with respect to the working artificial receptor such that the waveguide is capable of receiving light from the working artificial receptor. The detection system can be configured to detect the electromagnetic radiation. The system can be configured to detect pathogenic microorganism, cancerous cell, pollutant in water, airborne pollutant, explosive-related vapor, protein, polynucleotide, or mixture thereof.Type: GrantFiled: September 3, 2004Date of Patent: December 23, 2008Assignee: Receptors LLCInventor: Robert E. Carlson
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Publication number: 20040235051Abstract: The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building block compounds, typically immobilized in a spot on a support. The present invention also includes the building blocks, combinations of building blocks, arrays of building blocks, and receptors constructed of these building blocks together with a support. The present invention also includes methods of making and using these arrays and receptors.Type: ApplicationFiled: December 2, 2003Publication date: November 25, 2004Applicant: Receptors LLCInventor: Robert E. Carlson
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Publication number: 20040137481Abstract: The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building block compounds, typically immobilized in a spot on a support. The present invention also includes the building blocks, combinations of building blocks, arrays of building blocks, and receptors constructed of these building blocks together with a support. The present invention also includes methods of making and using these arrays and receptors.Type: ApplicationFiled: November 7, 2003Publication date: July 15, 2004Applicant: Receptors LLCInventor: Robert E. Carlson
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Publication number: 20040110303Abstract: The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building block compounds, typically immobilized in a spot on a support. The present invention also includes the building blocks, combinations of building blocks, arrays of building blocks, and receptors constructed of these building blocks together with a support. The present invention also includes methods of making and using these arrays and receptors.Type: ApplicationFiled: November 11, 2003Publication date: June 10, 2004Applicant: Receptors LLCInventor: Robert E. Carlson
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Publication number: 20040101446Abstract: The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building block compounds, typically immobilized in a spot on a support. The present invention also includes the building blocks, combinations of building blocks, arrays of building blocks, and receptors constructed of these building blocks together with a support. The present invention also includes methods of making and using these arrays and receptors.Type: ApplicationFiled: November 7, 2003Publication date: May 27, 2004Applicant: Receptors LLCInventor: Robert E. Carlson
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Publication number: 20040096976Abstract: The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building block compounds, typically immobilized in a spot on a support. The present invention also includes the building blocks, combinations of building blocks, arrays of building blocks, and receptors constructed of these building blocks together with a support. The present invention also includes methods of making and using these arrays and receptors.Type: ApplicationFiled: November 11, 2003Publication date: May 20, 2004Applicant: Receptors LLCInventor: Robert E. Carlson
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Publication number: 20040096908Abstract: The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building block compounds, typically immobilized in a spot on a support. The present invention also includes the building blocks, combinations of building blocks, arrays of building blocks, and receptors constructed of these building blocks together with a support. The present invention also includes methods of making and using these arrays and receptors.Type: ApplicationFiled: November 7, 2003Publication date: May 20, 2004Applicant: Receptors LLCInventor: Robert E. Carlson
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Patent number: D1043987Type: GrantFiled: September 16, 2021Date of Patent: September 24, 2024Assignee: SOMNETICS INTERNATIONAL, INC.Inventors: Paul R. Williams, Jr., Charles R. Lewis, Jr., Robert E. Simon, Andrew J. Carlson