Patents by Inventor Robert E. Cunningham

Robert E. Cunningham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8481283
    Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: July 9, 2013
    Assignees: The United States of America as Represented by the Department of Veterans Affairs, The United States of America as Represented by the Secretary of Defense on behalf of the Armed Forces Institute of Pathology, American Registry of Pathology
    Inventors: Timothy J. O'Leary, Jeffrey T. Mason, Carol B. Fowler, Robert E. Cunningham
  • Publication number: 20130011854
    Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 10, 2013
    Inventors: Timothy J. O'Leary, Jeffrey T. Mason, Carol B. Fowler, Robert E. Cunningham
  • Patent number: 8288122
    Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: October 16, 2012
    Assignees: The United States of America as Represented by the Department of Veterans Affairs, The United States of America as Represented by the Secretary of Defense on behalf of the Armed Forces Institute of Pathology, American Registry of Pathology
    Inventors: Timothy J. O'Leary, Jeffrey T. Mason, Carol B. Fowler, Robert E. Cunningham
  • Patent number: 7896326
    Abstract: An article, method, and kit for holding an object in place on a wall that include a jig with a support member and a platform member that is coupled to, and extends perpendicularly from, the support member. The support member has a top end including a portion adapted to be positioned behind a wall-facing surface of an object placed upon the platform member and an opening that is adapted to removably engage a coupling device on or in a wall such that the support member is disposed in a substantially vertical hanging position upon the wall. The jig may further include a brace member that forms a triangle by connecting a lower side of the platform member to the support member.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: March 1, 2011
    Inventor: Robert E. Cunningham
  • Publication number: 20100136613
    Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
    Type: Application
    Filed: December 3, 2009
    Publication date: June 3, 2010
    Inventors: Timothy J. O'Leary, Jeffrey T. Mason, Carol B. Fowler, Robert E. Cunningham
  • Publication number: 20090008849
    Abstract: An article, method, and kit for holding an object in place on a wall that include a jig with a support member and a platform member that is coupled to, and extends perpendicularly from, the support member. The support member has a top end including a portion adapted to be positioned behind a wall-facing surface of an object placed upon the platform member and an opening that is adapted to removably engage a coupling device on or in a wall such that the support member is disposed in a substantially vertical hanging position upon the wall. The jig may further include a brace member that forms a triangle by connecting a lower side of the platform member to the support member.
    Type: Application
    Filed: July 3, 2007
    Publication date: January 8, 2009
    Inventor: Robert E. Cunningham
  • Patent number: 5041992
    Abstract: A system and method for interactive design of user manipulable graphic elements. A computer has display and stored tasks wherein the appearance of graphic elements and methods for their manipulation are defined. Each graphic element is defined by at least one figure specification, one mask specification and one map specification. An interactive display editor program defines specifications of said graphic elements. An interactive program editor program defines programming data and methods associated with said graphic elements. A display program uses the figure, map and mask specifications for assembling graphic elements upon the display and enabling user manipulation of said graphic elements.
    Type: Grant
    Filed: October 24, 1988
    Date of Patent: August 20, 1991
    Assignee: University of Pittsburgh
    Inventors: Robert E. Cunningham, Jeffery G. Bonar, John D. Corbett
  • Patent number: 4696986
    Abstract: It has been determined that 1,2,3-trialkoxybenzenes and 1,2,4-trialkoxybenzenes can be utilized in order to increase the vinyl content of polydienes which are prepared utilizing lithium catalyst systems. For instance, it has been determined that 1,2,3-trimethoxybenzene and 1,2,4-trimethoxybenzene are very strong modifiers for utilization in such polymerizations. The utilization of the trialkoxybenzene modifiers of the present invention is highly advantageous because they promote fast polymerization rates and can be used to produce polymers having high vinyl contents.
    Type: Grant
    Filed: August 12, 1986
    Date of Patent: September 29, 1987
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: Adel F. Halasa, Robert E. Cunningham
  • Patent number: 4517505
    Abstract: An object of the invention is to provide variable damping for resonant vibrations which may occur at different rotational speeds in the range of rpms in which a rotating machine is operated.A variable force damper in accordance with the invention includes a rotating mass (12) carried on a shaft (11) which is supported by a bearing (13) in a resilient cage (14). Cage (14) is attached to a support plate (15) whose rim extends into an annular groove in a housing (17).Variable damping is effected by tabs (18) of electrically conducting, non-magnetic material which extend radially from the cage (14). The tabs (18) at an index position lie between the pole faces of respective C-shaped magnets (19). The magnets (19) are attached by cantilever spring members (20) to the housing (17).By rotating the support plate (15) about the axis of shaft (11), the tabs (18) may be rotated through an angle 0 of about 40.degree. away from the index or 0.degree. position. At the 40.degree. position minimum damping is obtained.
    Type: Grant
    Filed: February 3, 1983
    Date of Patent: May 14, 1985
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventor: Robert E. Cunningham
  • Patent number: 4197507
    Abstract: A supressing pulse synthesizer for supplying the proper average number of nchronization pulses from a reproduced reference signal to an analog to digital converter utilized to convert analog data present on a magnetic tape to digital data.
    Type: Grant
    Filed: April 7, 1978
    Date of Patent: April 8, 1980
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Robert E. Cunningham, Philip H. Bush
  • Patent number: 4104331
    Abstract: There is disclosed a method of preparing a five-membered block polymer, said block polymer exhibiting more superior properties than would be expected from copolymers made from similar blocks.
    Type: Grant
    Filed: September 24, 1975
    Date of Patent: August 1, 1978
    Assignee: The Goodyear Tire & Rubber Company
    Inventor: Robert E. Cunningham
  • Patent number: 4097557
    Abstract: There is disclosed an improved method of preparing ABC block polymers, wherein A is .alpha.-methylstyrene, B is a conjugated diene, and C is styrene or a substituted styrene.
    Type: Grant
    Filed: August 6, 1973
    Date of Patent: June 27, 1978
    Assignee: The Goodyear Tire & Rubber Company
    Inventor: Robert E. Cunningham
  • Patent number: 4035037
    Abstract: A hydrostatic bearing support system is provided which comprises a bearing housing having a polygonally configured outer surface which defines at least three symmetrically disposed working faces and a plurality of pressure plates, each of which is disposed relatively opposite a corresponding working face and spaced therefrom to define a gap therebetween. A hydrostatic support film is created in the gap for supporting the housing in spaced relationship to the pressure plates.
    Type: Grant
    Filed: March 2, 1976
    Date of Patent: July 12, 1977
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventor: Robert E. Cunningham
  • Patent number: D414312
    Type: Grant
    Filed: September 14, 1998
    Date of Patent: September 28, 1999
    Inventor: Robert E Cunningham