Patents by Inventor Robert E. Enns

Robert E. Enns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation and cloning of the human ARSA-I gene and uses thereof
    Patent number: 5928926
    Abstract: The present invention provides DNA encoding a human ARSA-I protein selected from the group consisting of: (a) isolated DNA which encodes a human ARSA-I protein; (b) isolated DNA which hybridizes to isolated DNA of (a) above and which encodes a human ARSA-I protein; and (c) isolated DNA differing from the isolated DNAs of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a human ARSA-I protein. Also provided are pharmaceutical compositions comprising human human ARSA-I protein and a pharmaceutically acceptable carrier and host cells transfected with the vector of the present invention said vector expressing a human ARSA-I protein.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: July 27, 1999
    Assignee: Research Development Foundation
    Inventors: Buran Kurdi-Haidar, Stephen B. Howell, Robert E. Enns, Peter Naredi
  • Diagnostic assay based on cis-plain drug resistance gene
    Patent number: 5434046
    Abstract: This invention relates to DNA encoding drug resistance to cis-platin. The invention also includes expression products of, and vectors and hosts comprising the DNA sequence encoding cis-platin resistance. Also included are immunodiagnostic assays of cis-platin resistance and assays for screening materials having a modulating effect on DNA encoding the cis-platin resistance gene and on the expression product thereof. The invention is further directed to antagonists to the cis-platin resistance gene and the expression product thereof. Recombinant and pharmaceutical means making use of the cis-platin resistance gene and its expression product are also provided.
    Type: Grant
    Filed: March 8, 1993
    Date of Patent: July 18, 1995
    Assignee: The Regents of the University of California
    Inventors: Robert E. Enns, Stephen B. Howell